{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T06:10:59Z","timestamp":1790748659296,"version":"4.1.0"},"reference-count":33,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2024,2,8]],"date-time":"2024-02-08T00:00:00Z","timestamp":1707350400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: We retrospectively investigated the effects of the severity and classification of sleep-disordered breathing (SDB) on left ventricular (LV) function in patients with ST-segment elevation myocardial infarction (STEMI). Methods: A total of 115 patients with STEMIs underwent a sleep study using a multichannel frontopolar electroencephalography recording device (Sleep Profiler) one week after STEMI onset. We evaluated LV global longitudinal strain (LV-GLS) using two-dimensional echocardiography at one week and seven months. Patients were classified as no SDB (AHI &lt; 5 events\/h), obstructive SDB (over 50% of apnea events are obstructive), and central SDB (over 50% of apnea events are central). Due to the device\u2019s limitations in distinguishing obstructive from central hypopnea, SDB classification was based on apnea index percentages. Results: The obstructive apnea index (OAI) was significantly associated with LV-GLS at one week (r = 0.24, p = 0.027) and seven months (r = 0.21, p = 0.020). No such correlations were found for the central apnea index and SDB classification. Multivariable regression analysis showed that the OAI was independently associated with LV-GLS at one week (\u03b2 = 0.24, p = 0.002) and seven months (\u03b2 = 0.20, p = 0.008). Conclusions: OAI is associated with persistent LV dysfunction assessed by LV-GLS in STEMI.<\/jats:p>","DOI":"10.3390\/jcm13040986","type":"journal-article","created":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T09:04:01Z","timestamp":1707469441000},"page":"986","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Influence of Obstructive Apnea Index on Persistent Left Ventricular Dysfunction in Patients with ST-Segment Elevation Myocardial Infarction"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0477-0323","authenticated-orcid":false,"given":"Jin","family":"Kirigaya","sequence":"first","affiliation":[{"name":"Department of Cardiology, Yokohama City University Medical Center, Yokohama 232-0024, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriaki","family":"Iwahashi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yokohama City University Medical Center, Yokohama 232-0024, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoaki","family":"Ishigami","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yokohama City University Hospital, Yokohama 236-0004, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeru","family":"Abe","sequence":"additional","affiliation":[{"name":"Advanced Critical Care and Emergency Center, Yokohama City University Medical Center, Yokohama 232-0024, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaomi","family":"Gohbara","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yokohama City University Medical Center, Yokohama 232-0024, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohei","family":"Hanajima","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yokohama City University Medical Center, Yokohama 232-0024, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mutsuo","family":"Horii","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yokohama City University Medical Center, Yokohama 232-0024, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kozo","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yokohama City University Medical Center, Yokohama 232-0024, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Matsuzawa","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yokohama City University Medical Center, Yokohama 232-0024, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masami","family":"Kosuge","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yokohama City University Medical Center, Yokohama 232-0024, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiaki","family":"Ebina","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yokohama City University Medical Center, Yokohama 232-0024, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyoshi","family":"Hibi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yokohama City University Hospital, Yokohama 236-0004, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1161\/CIRCULATIONAHA.115.019392","article-title":"Obstructive Sleep Apnea and Cardiovascular Events After Percutaneous Coronary Intervention","volume":"133","author":"Lee","year":"2016","journal-title":"Circulation"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e003270","DOI":"10.1161\/JAHA.116.003270","article-title":"Impact of Sleep-Disordered Breathing on Long-Term Outcomes in Patients with Acute Coronary Syndrome Who Have Undergone Primary Percutaneous Coronary Intervention","volume":"5","author":"Mazaki","year":"2016","journal-title":"J. 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