{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T19:37:04Z","timestamp":1785353824987,"version":"3.55.0"},"reference-count":53,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2024,2,17]],"date-time":"2024-02-17T00:00:00Z","timestamp":1708128000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>(1) Background: Prematurity is a serious condition associated with long-term neurological disability. This study aimed to compare the neurodevelopmental outcomes of preterm neonates with or without sepsis. (2) Methods: This single-center retrospective case\u2013control study included infants with birth weight &lt; 1500 g and\/or gestational age \u2264 30 weeks. Short-term outcomes, brain MRI findings, and severe functional disability (SFD) at age 24 months were compared between infants with culture-proven or culture-negative sepsis or without sepsis. A chi-squared test or Mann\u2013Whitney U test was used to compare the clinical and instrumental characteristics and the outcomes between cases and controls. (3) Results: Infants with sepsis (all sepsis n = 76; of which culture-proven n = 33 and culture-negative n = 43) were matched with infants without sepsis (n = 76). Compared with infants without sepsis, both all sepsis and culture-proven sepsis were associated with SFD. In multivariate logistic regression analysis, SFD was associated with intraventricular hemorrhage (OR 4.7, CI 1.7\u201313.1, p = 0.002) and all sepsis (OR 3.68, CI 1.2\u201311.2, p = 0.021). (4) Conclusions: All sepsis and culture-proven sepsis were associated with SFD. Compared with infants without sepsis, culture-negative sepsis was not associated with an increased risk of SFD. Given the association between poor outcomes and culture-proven sepsis, its prevention in the neonatal intensive care unit is a priority.<\/jats:p>","DOI":"10.3390\/jcm13041140","type":"journal-article","created":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T03:18:38Z","timestamp":1708312718000},"page":"1140","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Neurodevelopmental Outcome after Culture-Proven or So-Called Culture-Negative Sepsis in Preterm Infants"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1302-4944","authenticated-orcid":false,"given":"Luca","family":"Bedetti","sequence":"first","affiliation":[{"name":"Neonatal Intensive Care Unit, University Hospital of Modena, 41124 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2102-2674","authenticated-orcid":false,"given":"Lucia","family":"Corso","sequence":"additional","affiliation":[{"name":"Pediatric Postgraduate School, University of Modena and Reggio Emilia, 41121 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5991-8949","authenticated-orcid":false,"given":"Francesca","family":"Miselli","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit, University Hospital of Modena, 41124 Modena, Italy"},{"name":"PhD Program in Clinical and Experimental Medicine, University of Modena and Reggio Emilia, 41124 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isotta","family":"Guidotti","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit, University Hospital of Modena, 41124 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlotta","family":"Toffoli","sequence":"additional","affiliation":[{"name":"Pediatric Postgraduate School, University of Modena and Reggio Emilia, 41121 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rossella","family":"Miglio","sequence":"additional","affiliation":[{"name":"Department of Statistical Sciences, University of Bologna, 41121 Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Federica","family":"Roversi","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit, University Hospital of Modena, 41124 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa della Casa","family":"Muttini","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit, University Hospital of Modena, 41124 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marisa","family":"Pugliese","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit, University Hospital of Modena, 41124 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9275-8801","authenticated-orcid":false,"given":"Natascia","family":"Bertoncelli","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit, University Hospital of Modena, 41124 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommaso","family":"Zini","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit, University Hospital of Modena, 41124 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8005-4261","authenticated-orcid":false,"given":"Sofia","family":"Mazzotti","sequence":"additional","affiliation":[{"name":"Pediatric Postgraduate School, University of Modena and Reggio Emilia, 41121 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2149-0083","authenticated-orcid":false,"given":"Licia","family":"Lugli","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit, University Hospital of Modena, 41124 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Lucaccioni","sequence":"additional","affiliation":[{"name":"Pediatric Unit, Department of Medical and Surgical Sciences of the Mother, Children and Adults, University of Modena and Reggio Emilia, 41121 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3534-7499","authenticated-orcid":false,"given":"Alberto","family":"Berardi","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit, University Hospital of Modena, 41124 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1001\/jama.2013.3786","article-title":"Neurodevelopmental outcome in extremely preterm infants at 2.5 years after active perinatal care in Sweden","volume":"309","author":"Serenius","year":"2013","journal-title":"JAMA"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1056\/NEJMoa1605566","article-title":"Survival and neurodevelopmental outcomes among Periviable infants","volume":"376","author":"Younge","year":"2017","journal-title":"N. Engl. J. Med."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1056\/NEJMoa041367","article-title":"EPICure Study Group: Neurologic and developmental disability at six years of age after extremely preterm birth","volume":"352","author":"Marlow","year":"2005","journal-title":"N. Engl. J. Med."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"697100","DOI":"10.3389\/fped.2021.697100","article-title":"Neuroprem 2: An Italian Study of Neurodevelopmental Outcomes of Very Low Birth Weight Infants","volume":"9","author":"Lugli","year":"2021","journal-title":"Front. Pediatr."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1542\/peds.2010-2217","article-title":"Early onset neonatal sepsis: The burden of group B Streptococcal and E. coli disease continues","volume":"127","author":"Stoll","year":"2011","journal-title":"Pediatrics"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"e200593","DOI":"10.1001\/jamapediatrics.2020.0593","article-title":"Early-Onset Neonatal Sepsis 2015 to 2017, the Rise of Escherichia coli, and the Need for Novel Prevention Strategies","volume":"174","author":"Stoll","year":"2020","journal-title":"JAMA Pediatr."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Berardi, A., Sforza, F., Baroni, L., Spada, C., Ambretti, S., Biasucci, G., Bolognesi, S., Capretti, M., Carretto, E., and Ciccia, M. (2019). Epidemiology and complications of late-onset sepsis: An Italian area-based study. PLoS ONE, 14.","DOI":"10.1371\/journal.pone.0225407"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/S1473-3099(14)70710-8","article-title":"Infection-induced inflammation and cerebral injury in preterm infants","volume":"14","author":"Strunk","year":"2014","journal-title":"Lancet Infect. Dis."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.cmi.2023.04.017","article-title":"Long-term impact of serious neonatal bacterial infections on neurodevelopment","volume":"30","author":"Thomas","year":"2024","journal-title":"Clin. Microbiol. Infect."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1016\/j.ajog.2004.06.058","article-title":"Neonatal cerebral white matter injury in preterm infants is associated with culture positive infections and only rarely with metabolic acidosis","volume":"191","author":"Graham","year":"2004","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1056\/NEJMra2303347","article-title":"Defining the Neurologic Consequences of Preterm Birth","volume":"389","author":"Inder","year":"2023","journal-title":"N. Engl. J. Med."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"e372","DOI":"10.1542\/peds.2012-3979","article-title":"Neonatal infection and 5-year neurodevelopmental outcome of very preterm infants","volume":"132","author":"Mitha","year":"2013","journal-title":"Pediatrics"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"e348","DOI":"10.1542\/peds.2010-3338","article-title":"Impact of sepsis on neurodevelopmental outcome in a Swiss National Cohort of extremely premature infants","volume":"128","author":"Schlapbach","year":"2011","journal-title":"Pediatrics"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1038\/jp.2012.167","article-title":"Neurodevelopmental outcomes of very low birth weight infants with neonatal sepsis: Systematic review and meta-analysis","volume":"33","author":"Alshaikh","year":"2013","journal-title":"J. Perinatol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.jpeds.2022.01.006","article-title":"A Proposed Framework for the Clinical Management of Neonatal \u201cCulture-Negative\u201d Sepsis","volume":"244","author":"Cantey","year":"2022","journal-title":"J. Pediatr."},{"key":"ref_16","unstructured":"EFCNI\u2013European Standards of Care for Newborn Health (2023, March 15). Follow-up and Continuing Care. Available online: htps:\/\/newborn-health-standards.org\/standards\/standards-english\/follow-up-continuing-care."},{"key":"ref_17","first-page":"CD005495","article-title":"Early developmental intervention programmes provided post hospital discharge to prevent motor and cognitive impairment in preterm infants","volume":"2015","author":"Spittle","year":"2015","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1001\/jama.2016.0287","article-title":"The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)","volume":"315","author":"Singer","year":"2016","journal-title":"JAMA"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1016\/S0140-6736(17)31002-4","article-title":"Neonatal sepsis","volume":"390","author":"Shane","year":"2017","journal-title":"Lancet"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"S45","DOI":"10.1097\/01.PCC.0000161946.73305.0A","article-title":"Definitions of bloodstream infection in the newborn","volume":"6","author":"Haque","year":"2005","journal-title":"Pediatr. Crit. Care Med."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1055\/s-0033-1334886","article-title":"Nosocomial Infections in Very Low Birthweight Infants in Germany: Current Data from the National Surveillance System NEO-KISS","volume":"225","author":"Leistner","year":"2013","journal-title":"Klin. Padiatr."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1038\/s41390-021-01768-0","article-title":"Blood pressure, organ dysfunction, and mortality in preterm neonates with late-onset sepsis","volume":"92","author":"Zhu","year":"2022","journal-title":"Pediatr. Res."},{"key":"ref_23","unstructured":"Vermont-Oxford Network Database (2017). Manual of Operations, Data Definitions, Vermont Oxford Network."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.1001\/jama.292.19.2357","article-title":"Neurodevelopmental and growth impairment among extremely low-birth-weight infants with neonatal infection","volume":"292","author":"Stoll","year":"2004","journal-title":"JAMA"},{"key":"ref_25","first-page":"CD003481","article-title":"Ibuprofen for the treatment of patent ductus arteriosus in preterm or low birth weight (or both) infants","volume":"9","author":"Ohlsson","year":"2018","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1164\/ajrccm.163.7.2011060","article-title":"Bronchopulmonary dysplasia","volume":"163","author":"Jobe","year":"2001","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"e51","DOI":"10.1016\/j.ophtha.2021.05.031","article-title":"International Classification of Retinopathy of Prematurity, Third Edition","volume":"128","author":"Chiang","year":"2021","journal-title":"Ophthalmology"},{"key":"ref_28","unstructured":"Amiel-Tison, C., and Grenier, L. (1981). La Valutazione Neurologica del Neonato e del Lattante, Masson."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Griffiths, R. (1996). Griffiths Mental Developmental Scale-Revised: Birth to 2 Years (GMDS-R), Hogrefe.","DOI":"10.1037\/t03301-000"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.3174\/ajnr.A6666","article-title":"MRI Findings at Term-Corrected Age and Neurodevelopmental Outcomes in a Large Cohort of Very Preterm Infants","volume":"41","author":"Arulkumaran","year":"2020","journal-title":"Am. J. Neuroradiol."},{"key":"ref_31","unstructured":"Nizet, V., and Klein, J.O. (2010). Infectious Diseases of the Fetus and Newborn Infant, Elsevier."},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Miselli, F., Crestani, S., Maugeri, M., Passini, E., Spaggiari, V., Deonette, E., \u0106osi\u0107, B., Rossi, K., Roversi, M.F., and Bedetti, L. (2023). Late-Onset Sepsis Mortality among Preterm Infants: Beyond Time to First Antibiotics. Microorganisms, 11.","DOI":"10.3390\/microorganisms11020396"},{"key":"ref_33","first-page":"51","article-title":"Neonatal bacterial meningitis","volume":"62","author":"Berardi","year":"2010","journal-title":"Minerva Pediatr."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.jpeds.2015.11.017","article-title":"Neonatal Infection and Later Neurodevelopmental Risk in the Very Preterm Infant","volume":"170","author":"Rand","year":"2016","journal-title":"J. Pediatr."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1136\/archdischild-2020-320664","article-title":"NICHD Neonatal Research Network. Neurodevelopmental outcomes following neonatal late-onset sepsis and blood culture-negative conditions","volume":"106","author":"Mukhopadhyay","year":"2021","journal-title":"Arch. Dis. Child. Fetal Neonatal Ed."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"e20170044","DOI":"10.1542\/peds.2017-0044","article-title":"Ending the Culture of Culture-Negative Sepsis in the Neonatal ICU","volume":"140","author":"Cantey","year":"2017","journal-title":"Pediatrics"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1007\/s00431-019-03339-2","article-title":"Neurodevelopmental outcome at 2 years of age in preterm infants with late-onset sepsis","volume":"178","author":"Zonnenberg","year":"2019","journal-title":"Eur. J. Pediatr."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"F562","DOI":"10.1136\/archdischild-2015-309804","article-title":"The impact of a sepsis quality improvement project on neurodisability rates in very low birthweight infants","volume":"101","author":"Davis","year":"2016","journal-title":"Arch. Dis. Child. Fetal Neonatal Ed."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1007\/s00431-020-03844-9","article-title":"How to minimize central line-associated bloodstream infections in a neonatal intensive care unit: A quality improvement intervention based on a retrospective analysis and the adoption of an evidence-based bundle","volume":"180","author":"Bierlaire","year":"2021","journal-title":"Eur. J. Pediatr."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1053\/j.semperi.2017.03.006","article-title":"Central line-associated bloodstream infections in the NICU: Successes and controversies in the quest for zero","volume":"41","author":"Mobley","year":"2017","journal-title":"Semin. Perinatol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"e272","DOI":"10.1097\/pq9.0000000000000272","article-title":"Reduction of Central Line-associated Bloodstream Infection Through Focus on the Mesosystem: Standardization, Data, and Accountability","volume":"5","author":"Mathew","year":"2020","journal-title":"Pediatr. Qual. Saf."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"e20191105","DOI":"10.1542\/peds.2019-1105","article-title":"Newborn Antibiotic Exposures and Association with Proven Bloodstream Infection","volume":"144","author":"Schulman","year":"2019","journal-title":"Pediatrics"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.jpeds.2011.05.033","article-title":"Prolonged initial empirical antibiotic treatment is associated with adverse outcomes in premature infants","volume":"159","author":"Kuppala","year":"2011","journal-title":"J. Pediatr."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"e20182286","DOI":"10.1542\/peds.2018-2286","article-title":"Duration of Initial Empirical Antibiotic Therapy and Outcomes in Very Low Birth Weight Infants","volume":"143","author":"Ting","year":"2019","journal-title":"Pediatrics"},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Berardi, A., Zinani, I., Rossi, C., Spaggiari, E., D\u2019Amico, V., Toni, G., Bedetti, L., Lucaccioni, L., Iughetti, L., and Lugli, L. (2021). Antibiotic Use in Very Low Birth Weight Neonates After an Antimicrobial Stewardship Program. Antibiotics, 10.","DOI":"10.3390\/antibiotics10040411"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"e2022059427","DOI":"10.1542\/peds.2022-059427","article-title":"Reduction of Infection in Neonatal Intensive Care Units Using the Evidence-based Practice for Improving Quality (REIN-EPIQ) Study Group. Early Antibiotic Use and Neonatal Outcomes Among Preterm Infants Without Infections","volume":"151","author":"Yu","year":"2023","journal-title":"Pediatrics"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"e52","DOI":"10.1097\/PCC.0000000000002198","article-title":"Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children","volume":"21","author":"Weiss","year":"2020","journal-title":"Pediatr. Crit. Care Med."},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"(2018). Sepsis: Recognition, diagnosis and early management: \u00a9 NICE (2017). BJU Int., 121, 497\u2013514.","DOI":"10.1111\/bju.14179"},{"key":"ref_49","unstructured":"Spaggiari, V., Passini, E., Crestani, S., Roversi, M.F., Bedetti, L., Rossi, K., Lucaccioni, L., Baraldi, C., Muttini, E.D.C., and Lugli, L. (2022). Neonatal septic shock, a focus on first line interventions. Acta Biomed., 93."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1136\/archdischild-2018-315778","article-title":"Economic consequences of preterm birth: A systematic review of the recent literature (2009\u20132017)","volume":"104","author":"Petrou","year":"2019","journal-title":"Arch. Dis. Child."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s13052-015-0165-z","article-title":"Cost of care and social consequences of very low birth weight infants without premature- related morbidities in Italy","volume":"41","author":"Cavallo","year":"2015","journal-title":"Ital. J. Pediatr."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/ajo.13405","article-title":"The health and educational costs of preterm birth to 18 years of age in Australia","volume":"62","author":"Newnham","year":"2022","journal-title":"Aust. N. Z. J. Obstet. Gynaecol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"100277","DOI":"10.1016\/j.clinsp.2023.100277","article-title":"The financial impact of neonatal sepsis on the Brazilian Unified Health System","volume":"78","author":"Ogata","year":"2023","journal-title":"Clinics"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/4\/1140\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T14:01:24Z","timestamp":1760104884000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/4\/1140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,17]]},"references-count":53,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024,2]]}},"alternative-id":["jcm13041140"],"URL":"https:\/\/doi.org\/10.3390\/jcm13041140","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,17]]}}}