{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T15:13:52Z","timestamp":1788966832260,"version":"build-2803163510"},"reference-count":70,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2024,2,22]],"date-time":"2024-02-22T00:00:00Z","timestamp":1708560000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>The aim of the present systematic review was to investigate the clinical outcomes after the perforation of the maxillary sinus by dental implants, or after maxillary sinus membrane perforation during sinus lift procedure. Twenty-nine publications were included. Failure rates of implants in cases where perforation of sinus floor had happened (11 studies) was generally low, and only one case of transient sinusitis was reported. The estimated failure rate of these implants was 2.1% (SE 1.0%, p = 0.035). There were 1817 implants (73 failures) placed in augmented sinuses in which the sinus membrane was perforated and 5043 implants (274 failures) placed in sinuses with no perforated membrane, from 18 studies. The odds of implant failure difference between the groups were not significant (OR 1.347, p = 0.197). log OR of implant failure between perforated and non-perforated membrane groups did not significantly change with the follow-up time (\u22120.004\/month; p = 0.500). In conclusion, implant failure rate is generally low either for implants penetrating in the floor of the maxillary sinus or implants placed in augmented sinuses in which the sinus membrane was perforated. The prevalence of postoperative infection\/sinusitis is low, and it may depend either on the dimensions of the perforation or on the anatomical predisposition.<\/jats:p>","DOI":"10.3390\/jcm13051253","type":"journal-article","created":{"date-parts":[[2024,2,22]],"date-time":"2024-02-22T08:34:35Z","timestamp":1708590875000},"page":"1253","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Clinical Outcomes of Maxillary Sinus Floor Perforation by Dental Implants and Sinus Membrane Perforation during Sinus Augmentation: A Systematic Review and Meta-Analysis"],"prefix":"10.3390","volume":"13","author":[{"given":"Yousef Mohamed","family":"Sala","sequence":"first","affiliation":[{"name":"Faculty of Odontology, Malm\u00f6 University, SE-214 21 Malm\u00f6, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Lu","sequence":"additional","affiliation":[{"name":"Faculty of Odontology, Malm\u00f6 University, SE-214 21 Malm\u00f6, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3460-3374","authenticated-orcid":false,"given":"Bruno Ramos","family":"Chrcanovic","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery and Oral Medicine, Faculty of Odontology, Malm\u00f6 University, SE-214 21 Malm\u00f6, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"407","DOI":"10.11607\/jomi.9215","article-title":"Evaluation of Sinus Pneumatization and Dental Implant Placement in Atrophic Maxillary Premolar and Molar Regions","volume":"37","year":"2022","journal-title":"Int. J. Oral. Maxillofac. Implant."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.otohns.2004.11.012","article-title":"The analysis of maxillary sinus aeration according to aging process; volume assessment by 3-dimensional reconstruction by high-resolutional CT scanning","volume":"132","author":"Jun","year":"2005","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"ref_3","first-page":"48","article-title":"Maxillary sinus pneumatization following extractions: A radiographic study","volume":"23","author":"Sharan","year":"2008","journal-title":"Int. J. Oral. Maxillofac. Implant."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1111\/cid.12521","article-title":"Dimensional changes of the maxillary sinus following tooth extraction in the posterior maxilla with and without socket preservation","volume":"19","author":"Levi","year":"2017","journal-title":"Clin. Implant. Dent. Relat. Res."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"219","DOI":"10.11607\/ijp.5142","article-title":"Bone Quality and Quantity and Dental Implant Failure: A Systematic Review and Meta-analysis","volume":"30","author":"Chrcanovic","year":"2017","journal-title":"Int. J. Prosthodont."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/j.jcms.2019.01.030","article-title":"Clinical outcomes of pterygoid implants: Systematic review and meta-analysis","volume":"47","author":"Araujo","year":"2019","journal-title":"J. Craniomaxillofac Surg."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10006-012-0316-y","article-title":"Zygomatic implants: A critical review of the surgical techniques","volume":"17","author":"Chrcanovic","year":"2013","journal-title":"Oral. Maxillofac. Surg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1563\/AAID-JOI-D-10-00200","article-title":"Rehabilitation of the atrophic posterior maxilla with pterygoid implants: A review","volume":"38","author":"Candel","year":"2012","journal-title":"J. Oral. Implantol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s10006-012-0331-z","article-title":"Survival and complications of zygomatic implants: A systematic review","volume":"17","author":"Chrcanovic","year":"2013","journal-title":"Oral. Maxillofac. Surg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1563\/AAID-JOI-D-09-00074","article-title":"Accuracy evaluation of computed tomography-derived stereolithographic surgical guides in zygomatic implant placement in human cadavers","volume":"36","author":"Chrcanovic","year":"2010","journal-title":"J. Oral. Implantol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1111\/j.1600-0501.2008.01598.x","article-title":"Influence of residual alveolar bone height on osseointegration of implants in the maxilla: A pilot study","volume":"20","author":"Fenner","year":"2009","journal-title":"Clin. Oral. Implant. Res."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/j.1708-8240.2003.tb00298.x","article-title":"Maxillary sinus elevation surgery: An overview","volume":"15","author":"Kaufman","year":"2003","journal-title":"J. Esthet. Restor. Dent."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"220","DOI":"10.5125\/jkaoms.2019.45.4.220","article-title":"A review of complications of maxillary sinus augmentation and available treatment methods","volume":"45","author":"Kim","year":"2019","journal-title":"J. Korean Assoc. Oral. Maxillofac. Surg."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s40729-019-0157-7","article-title":"Influence of exposing dental implants into the sinus cavity on survival and complications rate: A systematic review","volume":"5","author":"Ragucci","year":"2019","journal-title":"Int. J. Implant. Dent."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"n160","DOI":"10.1136\/bmj.n160","article-title":"PRISMA 2020 explanation and elaboration: Updated guidance and exemplars for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"ref_16","unstructured":"NIH (2020, January 15). Quality Assessment Tool for Case Series Studies, Available online: https:\/\/www.nhlbi.nih.gov\/health-topics\/study-quality-assessment-tools."},{"key":"ref_17","first-page":"7","article-title":"Effectiveness of sinus lift procedures for dental implant rehabilitation: A Cochrane systematic review","volume":"3","author":"Esposito","year":"2010","journal-title":"Eur. J. Oral. Implantol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1600-0757.1994.tb00013.x","article-title":"Pathogenesis of implant failures","volume":"4","author":"Tonetti","year":"1994","journal-title":"Periodontol. 2000"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1111\/cid.12572","article-title":"Factors influencing the fracture of dental implants","volume":"20","author":"Chrcanovic","year":"2018","journal-title":"Clin. Implant. Dent. Relat. Res."},{"key":"ref_20","unstructured":"Egger, M., Smith, G.D., and Altman, D.G. (2003). Systematic Reviews in Health Care: Meta-Analysis in Context, BMJ Books."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v049.i05","article-title":"Closing the Gap between Methodologists and End-Users: R as a Computational Back-End","volume":"49","author":"Wallace","year":"2012","journal-title":"J. Stat. Softw."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1111\/2041-210X.12708","article-title":"OpenMEE: Intuitive, open-source software for meta-analysis in ecology and evolutionary biology","volume":"8","author":"Wallace","year":"2017","journal-title":"Methods Ecol. Evol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"2958","DOI":"10.1002\/lary.24189","article-title":"Potential adverse events of endosseous dental implants penetrating the maxillary sinus: Long-term clinical evaluation","volume":"123","author":"Malis","year":"2013","journal-title":"Laryngoscope"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"114","DOI":"10.4103\/ams.ams_42_20","article-title":"Effects of Corticobasal Implant Protrusion inside the Nasal and Maxillary Sinus","volume":"10","author":"Awadalkreem","year":"2020","journal-title":"Ann. Maxillofac. Surg."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Br\u00e5nemark27, P.I., Adell, R., Albrektsson, T., Lekholm, U., Lindstr\u00f6m, J., and Rockler, B. (1984). An experimental and clinical study of osseointegrated implants penetrating the nasal cavity and maxillary sinus. J. Oral. Maxillofac. Surg., 42, 497\u2013505.","DOI":"10.1016\/0278-2391(84)90008-9"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Chaves, L.L.V., Lopes Rosado, L.P., Piccolo, S.M., Ferreira, L.M., Kamburoglu, K., Junqueira, R.B., Aquino de Castro, M.A., and Verner, F.S. (2022). Evaluation of the Maxillary Sinus of Patients with Maxillary Posterior Implants: A CBCT Cross-Sectional Study. Diagnostics, 12.","DOI":"10.3390\/diagnostics12123169"},{"key":"ref_27","first-page":"207","article-title":"Clinical and Radiographic Evaluation of Dental implants Penetrating the Maxillary Sinus","volume":"10","author":"Awad","year":"2017","journal-title":"J. Int. Dent. Med. Res."},{"key":"ref_28","first-page":"2","article-title":"The influence of exposing dental implants to the maxillary sinus cavity on sinus complications and implant survival rate: 6 years prospective follow-up","volume":"60","author":"Ghanem","year":"2014","journal-title":"Egypt. Dent. J."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.tripleo.2006.09.024","article-title":"A retrospective study of the effects on sinus complications of exposing dental implants to the maxillary sinus cavity","volume":"103","author":"Jung","year":"2007","journal-title":"Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"58","DOI":"10.5051\/jpis.2013.43.2.58","article-title":"Peri-implant bone length changes and survival rates of implants penetrating the sinus membrane at the posterior maxilla in patients with limited vertical bone height","volume":"43","author":"Kim","year":"2013","journal-title":"J. Periodontal Implant. Sci."},{"key":"ref_31","first-page":"28","article-title":"Effect of schneiderian membrane perforation on posterior maxillary implant survival","volume":"5","author":"Nooh","year":"2013","journal-title":"J. Int. Oral. Health"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.15218\/zjms.2017.001","article-title":"Intentional penetration of dental implants into the maxillary sinus: A retrospective study","volume":"21","author":"Shihab","year":"2017","journal-title":"Zanco J. Med. Sci."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1097\/SCS.0b013e31824dbd19","article-title":"Effects of exposing dental implant to the maxillary sinus cavity","volume":"23","author":"Tabrizi","year":"2012","journal-title":"J. Craniofac Surg."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"3291","DOI":"10.1097\/MS9.0000000000000870","article-title":"Influence of implant protrusion length and initial bone height on intrasinus bone gain in transalveolar sinus floor elevation without bone graft: A 2-year retrospective study","volume":"85","author":"Albash","year":"2023","journal-title":"Ann. Med. Surg."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.11607\/jomi.8447","article-title":"Early Failure Rate and Associated Risk Factors for Dental Implants Placed with and Without Maxillary Sinus Augmentation: A Retrospective Study","volume":"35","author":"Atarchi","year":"2020","journal-title":"Int. J. Oral. Maxillofac. Implant."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"e14","DOI":"10.1016\/j.tripleo.2009.10.047","article-title":"Sinus bone graft using new alloplastic bone graft material (Osteon)-II: Clinical evaluation","volume":"109","author":"Bae","year":"2010","journal-title":"Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s40729-018-0116-8","article-title":"Impact of surgical management in cases of intraoperative membrane perforation during a sinus lift procedure: A follow-up on bone graft stability and implant success","volume":"4","author":"Westhoff","year":"2018","journal-title":"Int. J. Implant. Dent."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1111\/j.1600-0501.2008.01612.x","article-title":"Prospective observation of 41 perforations of the Schneiderian membrane during sinus floor elevation","volume":"19","author":"Becker","year":"2008","journal-title":"Clin. Oral. Implant. Res."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"401","DOI":"10.11607\/jomi.4419","article-title":"Effect of Maxillary Sinus Membrane Perforation on Implant Survival Rate: A Retrospective Study","volume":"32","author":"Martinelli","year":"2017","journal-title":"Int. J. Oral. Maxillofac. Implant."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1902\/jop.2012.120458","article-title":"Effect of maxillary sinus membrane perforation on vital bone formation and implant survival: A retrospective study","volume":"84","author":"Froum","year":"2013","journal-title":"J. Periodontol."},{"key":"ref_41","first-page":"354","article-title":"Lateral window sinus augmentation: Complications and outcomes of 101 consecutive procedures","volume":"24","author":"Guerrero","year":"2015","journal-title":"Implant. Dent."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1600-0501.2007.01372.x","article-title":"Prevalence and management of Schneiderian membrane perforations during sinus-lift procedures","volume":"19","author":"Torradeflot","year":"2008","journal-title":"Clin. Oral. Implant. Res."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1902\/jop.2006.060102","article-title":"Effects of sinus membrane perforations on the success of dental implants placed in the augmented sinus","volume":"77","author":"Karabuda","year":"2006","journal-title":"J. Periodontol."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/s40902-016-0097-6","article-title":"Evaluation of clinical outcomes of implants placed into the maxillary sinus with a perforated sinus membrane: A retrospective study","volume":"38","author":"Kim","year":"2016","journal-title":"Maxillofac. Plast. Reconstr. Surg."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"178","DOI":"10.11607\/jomi.2739","article-title":"Relationship between prognosis of dental implants and maxillary sinusitis associated with the sinus elevation procedure","volume":"28","author":"Kim","year":"2013","journal-title":"Int. J. Oral. Maxillofac. Implant."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s10006-017-0611-8","article-title":"Preoperative chronic sinusitis as significant cause of postoperative infection and implant loss after sinus augmentation from a lateral approach","volume":"21","author":"Kozuma","year":"2017","journal-title":"Oral. Maxillofac. Surg."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1097\/ID.0b013e3182061a73","article-title":"Effect of sinus membrane perforation on dental implant integration: A retrospective study on 128 patients","volume":"20","author":"Oh","year":"2011","journal-title":"Implant. Dent."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1111\/cid.12752","article-title":"The clinical and radiographic outcomes of Schneiderian membrane perforation without repair in sinus elevation surgery","volume":"21","author":"Park","year":"2019","journal-title":"Clin. Implant. Dent. Relat. Res."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1111\/cid.13038","article-title":"Long-term effects of sinus membrane perforation on dental implants placed with transcrestal sinus floor elevation: A case-control study","volume":"23","author":"Park","year":"2021","journal-title":"Clin. Implant. Dent. Relat. Res."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1111\/cid.13281","article-title":"The transalveolar approach with the small segmentation method for inclined maxillary sinus floor elevation: A retrospective study","volume":"26","author":"Zhuang","year":"2023","journal-title":"Clin. Implant. Dent. Relat. Res."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1111\/cid.12528","article-title":"Assessment of the effectiveness of platelet rich fibrin in the treatment of Schneiderian membrane perforation","volume":"19","author":"Kaymaz","year":"2017","journal-title":"Clin. Implant. Dent. Relat. Res."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.joms.2006.10.047","article-title":"Bone formation at the maxillary sinus floor following simultaneous elevation of the mucosal lining and implant installation without graft material: An evaluation of 20 patients treated with 44 Astra Tech implants","volume":"65","author":"Thor","year":"2007","journal-title":"J. Oral. Maxillofac. Surg."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.tripleo.2005.10.061","article-title":"The effects of exposing dental implants to the maxillary sinus cavity on sinus complications","volume":"102","author":"Jung","year":"2006","journal-title":"Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod."},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Brandstaetter, T., Ziv, O., Sagy, I., Segal, N., Schneider, S., Givol, N., Levin, L., Zadik, Y., and Kordeluk, S. (2023). Perforating dental implants and maxillary sinus pathology. Oral. Maxillofac. Surg.","DOI":"10.1007\/s10006-023-01198-8"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1111\/joor.12415","article-title":"Turned versus anodised dental implants: A meta-analysis","volume":"43","author":"Chrcanovic","year":"2016","journal-title":"J. Oral. Rehabil."},{"key":"ref_56","first-page":"S123","article-title":"Long-term clinical outcome of implants with different surface modifications","volume":"11","author":"Wennerberg","year":"2018","journal-title":"Eur. J. Oral. Implantol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/s40729-021-00346-7","article-title":"Management of Schneiderian membrane perforations during maxillary sinus floor augmentation with lateral approach in relation to subsequent implant survival rates: A systematic review and meta-analysis","volume":"7","year":"2021","journal-title":"Int. J. Implant. Dent."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.joms.2013.07.020","article-title":"Correlation between Schneiderian membrane perforation and sinus lift graft outcome: A retrospective evaluation of 359 augmented sinus","volume":"72","author":"Nolan","year":"2014","journal-title":"J. Oral. Maxillofac. Surg."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.tripleo.2010.02.038","article-title":"Late signs and symptoms of maxillary sinusitis after sinus augmentation","volume":"110","author":"Manor","year":"2010","journal-title":"Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1034\/j.1600-0501.2003.140310.x","article-title":"Maxillary sinus floor elevation surgery. A clinical, radiographic and endoscopic evaluation","volume":"14","author":"Timmenga","year":"2003","journal-title":"Clin. Oral. Implant. Res."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/S0901-5027(05)80219-X","article-title":"Composite grafting of the maxillary sinus for placement of endosteal implants. A preliminary report of 48 patients","volume":"21","author":"Tidwell","year":"1992","journal-title":"Int. J. Oral. Maxillofac. Surg."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1016\/S0278-2391(97)90063-X","article-title":"Maxillary sinus function after sinus lifts for the insertion of dental implants","volume":"55","author":"Timmenga","year":"1997","journal-title":"J. Oral. Maxillofac. Surg."},{"key":"ref_63","first-page":"413","article-title":"Repair of the perforated sinus membrane with a resorbable collagen membrane: A human study","volume":"19","author":"Proussaefs","year":"2004","journal-title":"Int. J. Oral. Maxillofac. Implant."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1016\/j.joms.2008.01.027","article-title":"Anatomical and surgical findings and complications in 100 consecutive maxillary sinus floor elevation procedures","volume":"66","author":"Zijderveld","year":"2008","journal-title":"J. Oral. Maxillofac. Surg."},{"key":"ref_65","doi-asserted-by":"crossref","unstructured":"Abdel-Halim, M., Issa, D., and Chrcanovic, B.R. (2021). The Impact of Dental Implant Length on Failure Rates: A Systematic Review and Meta-Analysis. Materials, 14.","DOI":"10.3390\/ma14143972"},{"key":"ref_66","doi-asserted-by":"crossref","unstructured":"Al Ansari, Y., Shahwan, H., and Chrcanovic, B.R. (2022). Diabetes Mellitus and Dental Implants: A Systematic Review and Meta-Analysis. Materials, 15.","DOI":"10.3390\/ma15093227"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1111\/joor.13567","article-title":"Bruxism and dental implants: A systematic review and meta-analysis","volume":"51","author":"Ali","year":"2024","journal-title":"J. Oral. Rehabil."},{"key":"ref_68","doi-asserted-by":"crossref","unstructured":"Mustapha, A.D., Salame, Z., and Chrcanovic, B.R. (2021). Smoking and Dental Implants: A Systematic Review and Meta-Analysis. Medicina, 58.","DOI":"10.3390\/medicina58010039"},{"key":"ref_69","doi-asserted-by":"crossref","unstructured":"Sulaiman, N., Fadhul, F., and Chrcanovic, B.R. (2023). Bisphosphonates and Dental Implants: A Systematic Review and Meta-Analysis. Materials, 16.","DOI":"10.3390\/ma16186078"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"445","DOI":"10.11607\/ijp.5151","article-title":"Impact of Different Surgeons on Dental Implant Failure","volume":"30","author":"Chrcanovic","year":"2017","journal-title":"Int. J. Prosthodont."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/5\/1253\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T14:03:14Z","timestamp":1760104994000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/5\/1253"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,22]]},"references-count":70,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2024,3]]}},"alternative-id":["jcm13051253"],"URL":"https:\/\/doi.org\/10.3390\/jcm13051253","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,22]]}}}