{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T08:31:56Z","timestamp":1783585916350,"version":"3.55.0"},"reference-count":48,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2024,3,9]],"date-time":"2024-03-09T00:00:00Z","timestamp":1709942400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Pulmonary artery dilatation is described mostly in association with pulmonary hypertension. Patients\/Methods: Study analysis: 60 patients with pulmonary arterial hypertension in congenital heart disease (PAH-CHD); 64 with repaired tetralogy of Fallot\/pulmonary regurgitation (rTOF\/PR); and 80 healthy (NORMAL). Measured were: main pulmonary artery (MPA) diameter and MPA\/ascending aorta (Ao asc) ratio, by echocardiography (ECHO) and computer tomography or magnetic resonance imaging (CT\/MRI). Results: In MPA diameter, significant differences between PAH-CHD, rTOF\/PR, and NORMAL were found (median): 37 vs. 27 vs. 21 mm (p &lt; 0.0001). In MPA\/Ao asc ratio, there was a difference between PAH-CHD and NORMAL (median): 1.3 vs. 0.8 (p &lt; 0.0001), but not between rTOF\/PR and NORMAL: 0.74 vs. 0.8 (p = 0.3). Significant MPA dilatation (&gt;40 mm) was present: in PAH-CHD, 35% (ECHO) and 76.9% (CT\/MRI) of patients, while in rTOF\/PR, 3.1% (ECHO) and 7.8% (CT\/MRI). Severe MPA dilatation (&gt;50 mm) occurred only in PAH-CHD: 16.7% (ECHO) and 31.4% (CT\/MRI), while not in rTOF\/PR. There was a significant correlation between ECHO and CT\/MRI measurements, but ECHO was underestimated in all parameters. Conclusions: MPA dilatation due to pressure overload is more frequent and more severe; volume overload also leads to MPA dilatation but is less severe. The MPA\/Ao asc ratio is not reliable for MPA dilatation estimation in rTOF\/PR.<\/jats:p>","DOI":"10.3390\/jcm13061567","type":"journal-article","created":{"date-parts":[[2024,3,11]],"date-time":"2024-03-11T04:51:12Z","timestamp":1710132672000},"page":"1567","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Pulmonary Artery Dilatation Due to Pressure or Volume Overload in Congenital Heart Disease"],"prefix":"10.3390","volume":"13","author":[{"given":"Monika","family":"Kaldararova","sequence":"first","affiliation":[{"name":"Children\u2019s Cardiac Center, National Institute of Cardiovascular Diseases, Pod Krasnou Horkou 1, 833 48 Bratislava, Slovakia"},{"name":"Department of Adult Congenital Heart Diseases, National Institute of Cardiovascular Diseases and Slovak Medical University, Pod Krasnou Horkou 1, 833 48 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarina","family":"Bobocka","sequence":"additional","affiliation":[{"name":"Department of Adult Congenital Heart Diseases, National Institute of Cardiovascular Diseases and Slovak Medical University, Pod Krasnou Horkou 1, 833 48 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Kantorova","sequence":"additional","affiliation":[{"name":"Children\u2019s Cardiac Center, National Institute of Cardiovascular Diseases, Pod Krasnou Horkou 1, 833 48 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Drangova","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, National Institute of Cardiovascular Diseases and Slovak Medical University, Pod Krasnou Horkou 1, 833 48 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Polakova Mistinova","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, National Institute of Cardiovascular Diseases and Slovak Medical University, Pod Krasnou Horkou 1, 833 48 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1964-7612","authenticated-orcid":false,"given":"Filip","family":"Klauco","sequence":"additional","affiliation":[{"name":"Department of Adult Congenital Heart Diseases, National Institute of Cardiovascular Diseases and Slovak Medical University, Pod Krasnou Horkou 1, 833 48 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tereza","family":"Hlavata","sequence":"additional","affiliation":[{"name":"Department of Adult Congenital Heart Diseases, National Institute of Cardiovascular Diseases and Slovak Medical University, Pod Krasnou Horkou 1, 833 48 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Reptova","sequence":"additional","affiliation":[{"name":"Department of Adult Congenital Heart Diseases, National Institute of Cardiovascular Diseases and Slovak Medical University, Pod Krasnou Horkou 1, 833 48 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana","family":"Valkovicova","sequence":"additional","affiliation":[{"name":"Department of Adult Congenital Heart Diseases, National Institute of Cardiovascular Diseases and Slovak Medical University, Pod Krasnou Horkou 1, 833 48 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iveta","family":"Simkova","sequence":"additional","affiliation":[{"name":"Department of Adult Congenital Heart Diseases, National Institute of Cardiovascular Diseases and Slovak Medical University, Pod Krasnou Horkou 1, 833 48 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,3,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1161\/CIRCIMAGING.111.968610","article-title":"Reference values for normal pulmonary artery dimensions by noncontrast cardiac computed tomography: The Framingham Heart Study","volume":"5","author":"Truong","year":"2012","journal-title":"Circ. 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