{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T15:00:21Z","timestamp":1792594821121,"version":"4.5.0"},"reference-count":67,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2024,3,10]],"date-time":"2024-03-10T00:00:00Z","timestamp":1710028800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Schizophrenia (SCZ) patients have disproportionately poor oral health outcomes owing to a multidimensional set of factors, such as pathophysiology of the disease, drug-related adverse effects and lower utilization rate of dental healthcare services. The aim of the present observational study was to compare the indicators of dental and periodontal health in patients with SCZ to those of nonaffected healthy controls; furthermore, the influence of various anamnestic factors and lifestyle habits on oral health status were also assessed. Methods: A total of 50 SCZ patients\u2014in remission\u2014receiving treatment at the Department of Psychiatry, University of Szeged, were compared with 50 age- and gender-matched healthy controls attending the Faculty of Dentistry, University of Szeged. Participants\u2019 dental (decayed, missing and filled surfaces [DMF-S] and decayed, missing and filled teeth [DMF-T]) and periodontal (plaque index [%], bleeding on probing [BOP%], pocket depth [PD] and attachment loss [AL]) status was measured according to the World Health Organization (WHO) criteria. Results: In total, 74.0%, 80.0% and 78.0% of SCZ patients received second-generation antipsychotics, benzodiazepines and mood stabilizers, respectively. Patients with SCZ had significantly higher DMFs (81.30 \u00b1 40.16 vs. 61.64 \u00b1 40.56; p = 0.010), D (8.18 \u00b1 7.73 vs. 4.18 \u00b1 4.22; p &lt; 0.001) and DMF-T (18.20 \u00b1 8.36 vs. 14.42 \u00b1 8.21; p = 0.024) scores but significantly lower F (1.84 \u00b1 0.29 vs. 4.62 \u00b1 3.98; p &lt; 0.001) scores compared to the controls; male subjects had significantly lower DMFs (74.52 \u00b1 39.72 vs. 90.67 \u00b1 39.1; p = 0.020) and DMF-T (16.52 \u00b1 8.12 vs. 20.52 \u00b1 8.32; p = 0.031) scores. Additionally, SCZ patients had significantly higher plaque indices (56.96 \u00b1 23.19 vs. 27.44 \u00b1 17.53; p &lt; 0.001), BOP% (58.96 \u00b1 22.89 vs. 23.56 \u00b1 17.53; p &lt; 0.001), PD (2.84 \u00b1 0.67 vs. 2.19 \u00b1 0.49; p = 0.024) and AL (3.39 \u00b1 1.72 vs. 2.49 \u00b1 0.76; p &lt; 0.001) values compared to controls. Smoking &gt; 10 cigarettes\/day was associated with worse dental and periodontal indices, while consuming \u2265 4 units\/week of alcohol was associated with worse periodontal indices, respectively (p &lt; 0.05 in all cases). In contrast, coffee consumption rates and vitamin supplementation status had no significant effect on oral health status indicators. Conclusions: Our study highlights the overall poor oral health status of individuals affected by SCZ and the need for targeted preventive interventions.<\/jats:p>","DOI":"10.3390\/jcm13061584","type":"journal-article","created":{"date-parts":[[2024,3,11]],"date-time":"2024-03-11T04:51:12Z","timestamp":1710132672000},"page":"1584","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Oral Health Status and Factors Related to Oral Health in Patients with Schizophrenia: A Matched Case-Control Observational Study"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1167-2684","authenticated-orcid":false,"given":"Reza","family":"Aghasizadeh Sherbaf","sequence":"first","affiliation":[{"name":"Department of Oral Surgery, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64\u201366., 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George Michael","family":"Kaposv\u00e1ri","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64\u201366., 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9383-5952","authenticated-orcid":false,"given":"Katalin","family":"Nagy","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64\u201366., 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zolt\u00e1n P\u00e9ter","family":"\u00c1lmos","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Faculty of Medicine, University of Szeged, Kor\u00e1nyi fasor 8\u201310., 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0636-6313","authenticated-orcid":false,"given":"Zolt\u00e1n","family":"Bar\u00e1th","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64\u201366., 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danica","family":"Matusovits","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64\u201366., 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,3,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e101675","DOI":"10.1016\/j.eclinm.2022.101675","article-title":"Quantifying the global burden of mental disorders and their economic value","volume":"54","author":"Arias","year":"2022","journal-title":"EclinicalMedicine"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Solmi, M., Seitidis, G., Mavridis, D., Correll, C.U., Dragioti, E., Guimond, S., Tuominen, L., Darg\u00e9l, A., Carvalho, A.F., and Fornaro, M. 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