{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T08:56:18Z","timestamp":1765961778956,"version":"build-2065373602"},"reference-count":44,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T00:00:00Z","timestamp":1710374400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: The objective of this study was to evaluate the pain and inflammatory response in soft tissues using healing and prosthetic abutments of different diameters and lengths. Methods: The study population was rehabilitated with Astra Tech EV single implants (Dentsply Sirona, Atlantis, Dentsply Sirona S.A., Barcelona, Spain) of 4.2 and 4.8 millimetres in diameter in the upper and lower maxilla and loaded with custom abutments digitally designed using Dentsply Sirona\u2019s Virtual Atlantis Design software (Atlantis WebOrder, Dentsply Sirona S.A., Barcelona, Spain), version 4.6.5. The custom abutments had a larger diameter than the healing abutments to evaluate for biomarkers through ELISA. Results: Rehabilitations in the mandible and with healing abutments with diameters less than 4.29 mm and rehabilitators with diameters less than 2.18 mm elicited a higher pain and inflammatory response and, in turn, higher interleukin-1\u03b2 values. Conclusions: Greater inflammation was evident in cases in which healing abutments with reduced diameter were used compared to the same subsequent rehabilitation with prosthetic abutments with larger diameters.<\/jats:p>","DOI":"10.3390\/jcm13061669","type":"journal-article","created":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T04:47:05Z","timestamp":1710478025000},"page":"1669","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Quantification and Influence of IL-1\u03b2 on Pain and Inflammatory Response after Placement of a Cement\u2013Screw-Retained Restoration"],"prefix":"10.3390","volume":"13","author":[{"given":"Lady","family":"Arbelaez-Bonozo","sequence":"first","affiliation":[{"name":"Department of Stomatology, Faculty of Dentistry, University of Seville, 41009 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seraf\u00edn","family":"Maza-Solano","sequence":"additional","affiliation":[{"name":"Department of Stomatology, Faculty of Dentistry, University of Seville, 41009 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5196-1675","authenticated-orcid":false,"given":"Mar\u00eda","family":"Baus-Dom\u00ednguez","sequence":"additional","affiliation":[{"name":"Department of Stomatology, Faculty of Dentistry, University of Seville, 41009 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raquel","family":"G\u00f3mez-D\u00edaz","sequence":"additional","affiliation":[{"name":"Institute of Biomedicine of Seville, 41013 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gonzalo","family":"Ruiz-de-Leon-Pacheco","sequence":"additional","affiliation":[{"name":"Gregorio Mara\u00f1\u00f3n General University Hospital, 28007 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9302-7138","authenticated-orcid":false,"given":"Daniel","family":"Torres-Lagares","sequence":"additional","affiliation":[{"name":"Department of Stomatology, Faculty of Dentistry, University of Seville, 41009 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda-Angeles","family":"Serrera-Figallo","sequence":"additional","affiliation":[{"name":"Department of Stomatology, Faculty of Dentistry, University of Seville, 41009 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,3,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1111\/jerd.12714","article-title":"The esthetic biological contour concept for implant restoration emergence profile design","volume":"33","author":"Esquivel","year":"2021","journal-title":"J. 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