{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T23:34:59Z","timestamp":1792712099180,"version":"4.5.0"},"reference-count":24,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T00:00:00Z","timestamp":1710460800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>(1) Background: Atopic dermatitis (AD) is one of the most common inflammatory skin conditions, thus having a significant impact on the quality of life (QoL) of patients and their families. We performed a survey to gather more data to help describe the burden of AD in Lithuania and to help expand the treatment plan to this important aspect of the disease. (2) Methods: A cross-sectional study was conducted involving healthy and AD pediatric patients. The assessment instruments used were the Patient-Oriented Eczema Measure (POEM), QoL, and original questionnaires (the original questionnaire was designed by the authors to determine the demographics, medical history, and treatment methods of the respondents). (3) Results: This study included 302 participants in total: 247 AD patients (51% boys) and 55 non-AD patients (51% boys). The mean age for AD patients was 6.8 \u00b1 4.4. years, and this was 10.5 \u00b1 3.1 years for the control patients. A significant difference was found between the QoL questionnaire scores and the Family Dermatology Life Quality Index (FDLQI) score for the atopic dermatitis group (QoL: 6.3 \u00b1 5.6; FDLQI: 7.1 \u00b1 6.9) and controls (QoL 0.5 \u00b1 1.1; FDLQI 2.1 \u00b1 5.9) (p = 0.000). The mean QoL questionnaire score for severe AD was 14.3 \u00b1 6.2 (very large effect), that for moderate AD was 6.9 \u00b1 4.4 (moderate effect), and that for mild AD was 4.4 \u00b1 4.2 (small effect) (p = 0.000). (4) Conclusions: Our study revealed a moderate effect of AD on dermatology-related QoL in patients and their families. It has been shown that increased disease severity was associated with a greater impairment of QoL in both patients and patient\u2019s parents. The burden of AD in children and their parents is considerable and should be taken into account in the management of atopic dermatitis.<\/jats:p>","DOI":"10.3390\/jcm13061700","type":"journal-article","created":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T09:32:30Z","timestamp":1710495150000},"page":"1700","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["The Burden of Pediatric Atopic Dermatitis: Quality of Life of Patients and Their Families"],"prefix":"10.3390","volume":"13","author":[{"given":"Inga","family":"Kisieliene","sequence":"first","affiliation":[{"name":"Clinic of Infectious Diseases and Dermatovenereology, Vilnius University, 08411 Vilnius, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antanas","family":"Mainelis","sequence":"additional","affiliation":[{"name":"Faculty of Mathematics and Informatics, Vilnius University, 03225 Vilnius, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3236-6723","authenticated-orcid":false,"given":"Odilija","family":"Rudzeviciene","sequence":"additional","affiliation":[{"name":"Clinic of Children\u2019s Diseases, Faculty of Medicine, Vilnius University, 03101 Vilnius, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matilda","family":"Bylaite-Bucinskiene","sequence":"additional","affiliation":[{"name":"Clinic of Infectious Diseases and Dermatovenereology, Vilnius University, 08411 Vilnius, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0177-8722","authenticated-orcid":false,"given":"Andreas","family":"Wollenberg","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy, Augsburg University Hospital, 86156 Augsburg, Germany"},{"name":"Department of Dermatology and Allergy, Ludwig-Maximilian University of Munich, 80539 Munich, Germany"},{"name":"Comprehensive Center for Inflammation Medicine, University of Luebeck, 23562 Luebeck, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,3,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Hadi, H.A., Tarmizi, A.I., Khalid, K.A., Gajd\u00e1cs, M., Aslam, A., and Jamshed, S. 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