{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T03:31:52Z","timestamp":1774323112643,"version":"3.50.1"},"reference-count":23,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T00:00:00Z","timestamp":1712534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: The aim of this study is to report outcomes of eyelid full-thickness skin grafting augmentation in facial nerve palsy (FNP) patients younger than 50 years of age. Methods: In a retrospective, consecutive case series, nine eyelid skin grafts performed on eight FNP patients with skin contraction (five females; median age 42 years [range, 17\u201347]) are presented. In most cases, upper eyelid skin grafting was combined with levator recession and anterior lamellar repositioning. Lower eyelid skin grafting was combined with lower retractors recession in all cases. Functional and cosmetic outcomes were measured preoperatively and at early (1\u20133 months), intermediate (3\u20136 months), and late (\u226512 months) follow-up. Results: The corneal score improved at early follow-up (p = 0.03) and remained improved at late follow-up (p = 0.042). The gentle closure lagophthalmos was improved at late follow-up (p = 0.042). (p = 0.048). The grades of graft color, edge\/skin interface, and size improved at 3\u20136 months post-grafting and remained improved at late follow-up (p &lt; 0.05). Over the follow-up, four patients (50%) were recommended to have further surgical procedures. Conclusions: The preliminary results from this small cohort suggest that eyelid skin grafting is a viable option for young patients prioritizing cosmesis. This technique warrants consideration for its functional benefits.<\/jats:p>","DOI":"10.3390\/jcm13072142","type":"journal-article","created":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T06:04:58Z","timestamp":1712556298000},"page":"2142","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Eyelid Skin Grafting in Young Patients with Facial Nerve Palsy"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7580-2356","authenticated-orcid":false,"given":"Yinon","family":"Shapira","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Carmel Medical Center, Haifa 3436212, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katja","family":"Ullrich","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Queen Elizabeth Hospital, Adelaide, SA 5011, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sundas","family":"Masqood","sequence":"additional","affiliation":[{"name":"Corneoplastic Unit, Queen Victoria Hospital NHS Trust, East Grinstead RH19 3DZ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Okafor","sequence":"additional","affiliation":[{"name":"Corneoplastic Unit, Queen Victoria Hospital NHS Trust, East Grinstead RH19 3DZ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raman","family":"Malhotra","sequence":"additional","affiliation":[{"name":"Corneoplastic Unit, Queen Victoria Hospital NHS Trust, East Grinstead RH19 3DZ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,4,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1097\/IOP.0000000000000485","article-title":"Recession and Extirpation of the Lower Eyelid Retractors for Paralytic Lagophthalmos","volume":"31","author":"Compton","year":"2015","journal-title":"Ophthalmic Plast. Reconstr. Surg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1038\/eye.2017.174","article-title":"Outcomes of lower eyelid retractor recession and lateral horn lysis in lower eyelid elevation for facial nerve palsy","volume":"32","author":"Tan","year":"2018","journal-title":"Eye"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1097\/01.iop.0000235817.78695.6f","article-title":"Techniques for upper eyelid loading","volume":"22","author":"Mavrikakis","year":"2006","journal-title":"Ophthalmic Plast. Reconstr. Surg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.ophtha.2005.06.038","article-title":"A useful augmented lateral tarsal strip tarsorrhaphy for paralytic ectropion","volume":"113","author":"Chang","year":"2006","journal-title":"Ophthalmology"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"159","DOI":"10.3109\/01676830.2013.879905","article-title":"Transcaruncular medial canthal tendon plication with lower eyelid suture sling in facial nerve palsy","volume":"33","author":"Sira","year":"2014","journal-title":"Orbit"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1001\/archopht.125.3.374","article-title":"Transcaruncular medial canthal ligament plication for repair of lower eyelid malposition","volume":"125","author":"Elner","year":"2007","journal-title":"Arch. Ophthalmol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1136\/bjo.2003.019232","article-title":"The direct brow lift: Efficacy, complications, and patient satisfaction","volume":"88","author":"Booth","year":"2004","journal-title":"Br. J. Ophthalmol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"140","DOI":"10.3109\/01676830.2011.574770","article-title":"Subperiosteal midface lift: Its role in static lower eyelid reconstruction after chronic facial nerve palsy","volume":"30","author":"Graziani","year":"2011","journal-title":"Orbit"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1097\/IOP.0000000000000710","article-title":"Periorbital Autologous Fat Grafting in Facial Nerve Palsy","volume":"33","author":"Siah","year":"2017","journal-title":"Ophthalmic Plast. Reconstr. Surg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1038\/eye.2016.21","article-title":"Occurrence and severity of upper eyelid skin contracture in facial nerve palsy","volume":"30","author":"Ziahosseini","year":"2016","journal-title":"Eye"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1136\/bjophthalmol-2018-312311","article-title":"Functional and aesthetic outcomes of eyelid skin grafting in facial nerve palsy","volume":"103","author":"Maqsood","year":"2019","journal-title":"Br. J. Ophthalmol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1111\/ceo.13338","article-title":"Cicatricial ectropion surgery: A prospective study of long-term symptom control, patient satisfaction and anatomical success","volume":"46","author":"McKelvie","year":"2018","journal-title":"Clin. Exp. Ophthalmol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1136\/bjophthalmol-2015-307167","article-title":"CADS grading scale: Towards better grading of ophthalmic involvement in facial nerve paralysis","volume":"100","author":"Malhotra","year":"2016","journal-title":"Br. J. Ophthalmol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1097\/IOP.0000000000000803","article-title":"Validation of CADS grading Scale: An ophthalmic specific grading instrument for facial nerve palsy","volume":"33","author":"Tan","year":"2017","journal-title":"Ophthalmic Plast. Reconstr. Surg."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1097\/ICO.0b013e3181a9d0a9","article-title":"White-to-white corneal diameter in the tehran eye study","volume":"29","author":"Hashemi","year":"2010","journal-title":"Cornea"},{"key":"ref_16","first-page":"14","article-title":"Neurologic principles of edema in inactivity","volume":"16","author":"Trettin","year":"1992","journal-title":"Z. Lymphol. J. Lymphology"},{"key":"ref_17","unstructured":"Fay, A., and Dolman, P. (2014). Advances in Oto-Rhino-Laryngology, Elsevier Inc."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1038\/eye.2016.306","article-title":"Occurrence and severity of upper eyelid skin contracture in facial nerve palsy","volume":"31","author":"Volk","year":"2017","journal-title":"Eye"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1093\/brain\/66.4.237","article-title":"Three types of nerve injury","volume":"66","author":"Seddon","year":"1943","journal-title":"Brain"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1093\/brain\/74.4.491","article-title":"A classification of peripheral nerve injuries producing loss of function","volume":"74","author":"Sunderland","year":"1951","journal-title":"Brain"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1002\/lary.27481","article-title":"Facial Palsy-Specific Quality of Life in 920 Patients: Correlation With Clinician-Graded Severity and Predicting Factors","volume":"129","author":"Dusseldorp","year":"2019","journal-title":"Laryngoscope"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1054\/bjps.2000.3335","article-title":"Patterns of contraction in human full thickness skin grafts","volume":"53","author":"Stephenson","year":"2000","journal-title":"Br. J. Plast. Surg."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1097\/IOP.0000000000001356","article-title":"Analysis of Spontaneous Eyelid Blink Dynamics Using a 240 Frames per Second Smartphone Camera","volume":"35","author":"Godfrey","year":"2019","journal-title":"Ophthalmic Plast. Reconstr. Surg."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/7\/2142\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T14:24:46Z","timestamp":1760106286000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/7\/2142"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,8]]},"references-count":23,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2024,4]]}},"alternative-id":["jcm13072142"],"URL":"https:\/\/doi.org\/10.3390\/jcm13072142","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,8]]}}}