{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T18:46:45Z","timestamp":1792090005751,"version":"4.4.0"},"reference-count":69,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T00:00:00Z","timestamp":1715990400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institute for Health Research","doi-asserted-by":"publisher","award":["57936"],"award-info":[{"award-number":["57936"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>(1) Background: Gilles de la Tourette Syndrome (TS) is a neurodevelopmental disorder characterized by motor and vocal tics. Attention deficit and hyperactivity disorder (ADHD) is a common comorbidity of TS that adds further impairment. Cognitive-behavioural therapy (CBT) has shown efficacy in treating tics, yet its effectiveness in individuals with TS and comorbid ADHD remains unclear. Also, it is suggested that ADHD characteristics like executive dysfunction and inattention could hinder the response to CBT. This study aims to compare the response to CBT for tics and its maintenance six months post-therapy among TS individuals with and without ADHD symptoms. (2) Methods: In this study, 55 TS participants who completed 14-week CBT for tics were split into high (TS+) or low (TS\u2212) ADHD symptomatology groups. Outcomes were evaluated using the Yale Global Tic Severity Scale (YGTSS) regarding global tic severity and motor and vocal tic frequency post-CBT and at a 6-month follow-up. (3) Results: No significant group difference was found regarding improvements post-CBT (n = 55), nor the maintenance six months later (n = 45). (4) Conclusions: ADHD symptoms may not hinder the response to CBT or its maintenance, suggesting that TS individuals with ADHD symptoms may not require specialized CBT interventions.<\/jats:p>","DOI":"10.3390\/jcm13102975","type":"journal-article","created":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T06:31:58Z","timestamp":1716186718000},"page":"2975","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Impacts of ADHD Symptomatology on the Response to Cognitive-Behavioural Therapy with Gilles de la Tourette Syndrome Patients"],"prefix":"10.3390","volume":"13","author":[{"given":"Emmanuelle","family":"Mazur-Lain\u00e9","sequence":"first","affiliation":[{"name":"Centre de Recherche de l\u2019Institut Universitaire en Sant\u00e9 Mentale de Montr\u00e9al, Montr\u00e9al, QC H1N 3V2, Canada"},{"name":"D\u00e9partement de Psychologie, Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, QC H2V 2S9, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Houda","family":"Soubata","sequence":"additional","affiliation":[{"name":"Centre de Recherche de l\u2019Institut Universitaire en Sant\u00e9 Mentale de Montr\u00e9al, Montr\u00e9al, QC H1N 3V2, Canada"},{"name":"D\u00e9partement de Psychologie, Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, QC H2V 2S9, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7735-0330","authenticated-orcid":false,"given":"Julie B.","family":"Leclerc","sequence":"additional","affiliation":[{"name":"Centre de Recherche de l\u2019Institut Universitaire en Sant\u00e9 Mentale de Montr\u00e9al, Montr\u00e9al, QC H1N 3V2, Canada"},{"name":"D\u00e9partement de Psychologie, Universit\u00e9 du Qu\u00e9bec \u00e0 Montr\u00e9al, Montr\u00e9al, QC H2X 3P2, Canada"},{"name":"Groupe d\u2019\u00e9tude sur les Troubles Tic, d\u2019Accumulation Compulsive et Obsessionnel-Compulsif (GE-tic-tac-toc), Montr\u00e9al, QC H1N 3V2, Canada"},{"name":"Centre de Recherche du CIUSSS du Nord-de-l\u2019\u00cele-de-Montr\u00e9al, Montr\u00e9al, QC H4J 1C5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre J.","family":"Blanchet","sequence":"additional","affiliation":[{"name":"Centre de Recherche de l\u2019Institut Universitaire en Sant\u00e9 Mentale de Montr\u00e9al, Montr\u00e9al, QC H1N 3V2, Canada"},{"name":"Facult\u00e9 de M\u00e9decine Dentaire, D\u00e9partement de Stomatologie, Universit\u00e9 de Montr\u00e9al, Montreal, QC H3T 1J4, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kieron P.","family":"O\u2019Connor","sequence":"additional","affiliation":[{"name":"Centre de Recherche de l\u2019Institut Universitaire en Sant\u00e9 Mentale de Montr\u00e9al, Montr\u00e9al, QC H1N 3V2, Canada"},{"name":"Groupe d\u2019\u00e9tude sur les Troubles Tic, d\u2019Accumulation Compulsive et Obsessionnel-Compulsif (GE-tic-tac-toc), Montr\u00e9al, QC H1N 3V2, Canada"},{"name":"D\u00e9partement de Psychiatrie et Addictologie, Universit\u00e9 de Montr\u00e9al, Montreal, QC H3T 1J4, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3037-3890","authenticated-orcid":false,"given":"Marc E.","family":"Lavoie","sequence":"additional","affiliation":[{"name":"Centre de Recherche de l\u2019Institut Universitaire en Sant\u00e9 Mentale de Montr\u00e9al, Montr\u00e9al, QC H1N 3V2, Canada"},{"name":"Groupe d\u2019\u00e9tude sur les Troubles Tic, d\u2019Accumulation Compulsive et Obsessionnel-Compulsif (GE-tic-tac-toc), Montr\u00e9al, QC H1N 3V2, Canada"},{"name":"D\u00e9partement de Psychiatrie et Addictologie, Universit\u00e9 de Montr\u00e9al, Montreal, QC H3T 1J4, Canada"},{"name":"D\u00e9partement de Sciences Humaines, Lettres et Communication, Universit\u00e9 T\u00c9LUQ, Quebec, QC G1K 9H6, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,5,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1038\/sj.npp.1301528","article-title":"Mechanisms of dopaminergic and serotonergic neurotransmission in Tourette syndrome: Clues from an in vivo neurochemistry study with PET","volume":"33","author":"Wong","year":"2008","journal-title":"Neuropsychopharmacol. 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