{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T22:13:46Z","timestamp":1788041626916,"version":"build-2784847793"},"reference-count":20,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T00:00:00Z","timestamp":1716336000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: This study investigated risk factors for progression of deformity in pediatric congenital cervical scoliosis (CCS) and evaluated the correlation between congenital cervical curves and compensatory thoracic and lumbar curves. Methods: Medical records were retrospectively reviewed for 38 pediatric patients with CCS with a minimum 2-year follow-up. Curve progression was defined as &gt;10\u00b0 increase in cervical coronal curve angle between presentation and last follow-up. Results: A total of 38 patients (16 girls, 22 boys) with a mean age at presentation of 5.6 \u00b1 4.1 years met the inclusion criteria. Sixteen patients (42%) had curve progression with a mean follow-up of 3.1 \u00b1 3.0 years. At presentation, T1 slope was significantly larger among children with progressive deformities (p = 0.041). A total of 18 of the 38 patients with strictly cervical spine deformity were then selected for subanalysis to evaluate the progression of compensatory curves. Cervical major coronal curves were found to significantly correlate with lumbar major coronal curves (r = 0.409), C2 central sacral vertical line (CSVL) (r = 0.407), and C7-CSVL (r = 0.403) (p &lt; 0.05). Thoracic major coronal curves did not significantly correlate with cervical major coronal curves (r = 0.218) (p &gt; 0.05). Conclusion: In conclusion, 42% of osseous CCS curves progressed over time in the overall cohort, and high initial T1 slope was found to be most highly correlated with progression of cervical deformity. Cervical major coronal curves significantly correlated with lumbar curve magnitude but not with thoracic curve size in isolated CCS, possibly due to the increased flexibility of the lumbar spine which may allow greater compensatory balance and thus have a greater correlation with cervical curve magnitude and possibly progression.<\/jats:p>","DOI":"10.3390\/jcm13113039","type":"journal-article","created":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T07:56:11Z","timestamp":1716364571000},"page":"3039","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Risk Factors for Progression of Cervical Congenital Scoliosis and Associated Compensatory Curve Behavior"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3489-3770","authenticated-orcid":false,"given":"Amir A.","family":"Amanullah","sequence":"first","affiliation":[{"name":"Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA"},{"name":"Shriners Children\u2019s\u2013Philadelphia, Philadelphia, PA 19140, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taemin","family":"Oh","sequence":"additional","affiliation":[{"name":"Shriners Children\u2019s\u2013Philadelphia, Philadelphia, PA 19140, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5036-8781","authenticated-orcid":false,"given":"Brandon J.","family":"Toll","sequence":"additional","affiliation":[{"name":"Shriners Children\u2019s\u2013Philadelphia, Philadelphia, PA 19140, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akul","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Sports Medicine, Temple University Hospital, Philadelphia, PA 19140, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4206-610X","authenticated-orcid":false,"given":"Amer F.","family":"Samdani","sequence":"additional","affiliation":[{"name":"Shriners Children\u2019s\u2013Philadelphia, Philadelphia, PA 19140, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua M.","family":"Pahys","sequence":"additional","affiliation":[{"name":"Shriners Children\u2019s\u2013Philadelphia, Philadelphia, PA 19140, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew Jeongyoon","family":"Kim","sequence":"additional","affiliation":[{"name":"Shriners Children\u2019s\u2013Philadelphia, Philadelphia, PA 19140, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aniketh","family":"Vellanki","sequence":"additional","affiliation":[{"name":"Shriners Children\u2019s\u2013Philadelphia, Philadelphia, PA 19140, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Steindler","sequence":"additional","affiliation":[{"name":"Shriners Children\u2019s\u2013Philadelphia, Philadelphia, PA 19140, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terrence G.","family":"Ishmael","sequence":"additional","affiliation":[{"name":"Shriners Children\u2019s\u2013Philadelphia, Philadelphia, PA 19140, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven W.","family":"Hwang","sequence":"additional","affiliation":[{"name":"Shriners Children\u2019s\u2013Philadelphia, Philadelphia, PA 19140, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,5,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e172","DOI":"10.1097\/BPO.0000000000000922","article-title":"What\u2019s new in congenital scoliosis?","volume":"38","author":"Pahys","year":"2018","journal-title":"J. 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