{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T01:39:09Z","timestamp":1790386749498,"version":"4.1.0"},"reference-count":90,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T00:00:00Z","timestamp":1717027200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Department of Adult Psychiatry","award":["503\/1-062-02\/503-51-001-19-00"],"award-info":[{"award-number":["503\/1-062-02\/503-51-001-19-00"]}]},{"name":"Department of Adult Psychiatry","award":["503\/5-062-02\/503-51-001-19-00"],"award-info":[{"award-number":["503\/5-062-02\/503-51-001-19-00"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Depressive disorders are a growing problem worldwide. They are also characterized by high comorbidity, including from the circle of dermatological diseases. Autoimmune diseases seem to be particularly correlated with depressive comorbidity, raising the question of their possible common pathomechanism. The PubMed database was searched, focusing on results published after 2016. A particular reciprocal correlation of depressive disorders with psoriasis, atopic dermatitis, alopecia areata, impetigo, lupus and systemic scleroderma was found. One possible explanation for the co-occurrence of the above diseases is that the inflammatory theory may be applicable to depression, the various elements of which also apply to autoimmune diseases.<\/jats:p>","DOI":"10.3390\/jcm13113224","type":"journal-article","created":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T06:08:14Z","timestamp":1717049294000},"page":"3224","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Depressive Disorder and Dermatological Autoimmune Diseases"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5863-2486","authenticated-orcid":false,"given":"Zuzanna","family":"Pe\u0142a","sequence":"first","affiliation":[{"name":"Department of Adult Psychiatry, Medical University of Lodz, 92-213 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Ga\u0142ecka","sequence":"additional","affiliation":[{"name":"Department of Adult Psychiatry, Medical University of Lodz, 92-213 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Murgrabia","sequence":"additional","affiliation":[{"name":"Department of Adult Psychiatry, Medical University of Lodz, 92-213 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aneta","family":"Kondratowicz","sequence":"additional","affiliation":[{"name":"Department of Adult Psychiatry, Medical University of Lodz, 92-213 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2447-5636","authenticated-orcid":false,"given":"Piotr","family":"Ga\u0142ecki","sequence":"additional","affiliation":[{"name":"Department of Adult Psychiatry, Medical University of Lodz, 92-213 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,5,30]]},"reference":[{"key":"ref_1","unstructured":"(2024, February 19). ZUS Poland. Available online: https:\/\/www.zus.pl\/-\/27-mln-zwolnie\u0144-lekarskich-w-2022-r."},{"key":"ref_2","unstructured":"WHO (2024, February 16). Depression. Available online: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/depression."},{"key":"ref_3","unstructured":"(2024, April 20). ICD 1-11. Available online: https:\/\/icd.who.int\/ct\/icd11_mms\/en\/release."},{"key":"ref_4","first-page":"17","article-title":"Wsp\u00f3\u0142istnienie chor\u00f3b somatycznych i depresji","volume":"4","author":"Dudek","year":"2007","journal-title":"Psychiatria"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/7854_2016_7","article-title":"Depression in Autoimmune Diseases","volume":"31","author":"Pryce","year":"2017","journal-title":"Curr. Top Behav. Neurosci."},{"key":"ref_6","first-page":"93","article-title":"Atopic dermatitis and psychosocial comorbidities","volume":"18","author":"Kage","year":"2020","journal-title":"J. Der Dtsch. Dermatol. Ges."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1038\/jid.2014.530","article-title":"The psychological burden of skin diseases: A cross-sectional multicenter study among dermatological out-patients in 13 European countries","volume":"135","author":"Dalgard","year":"2015","journal-title":"J. Investig. Dermatol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.jad.2020.05.070","article-title":"Association between major depressive disorder and subsequent autoimmune skin diseases: A nationwide population-based cohort study","volume":"274","author":"Dai","year":"2020","journal-title":"J. Affect. Disord."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"adv00699","DOI":"10.2340\/actadv.v102.1991","article-title":"Sleep Disorders and Psoriasis: An Update","volume":"102","author":"Halioua","year":"2022","journal-title":"Acta Dermato-Venereol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1016\/S0140-6736(20)32549-6","article-title":"Psoriasis","volume":"397","author":"Griffiths","year":"2021","journal-title":"Lancet"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"80","DOI":"10.2340\/00015555-3387","article-title":"Psoriasis and Co-morbidity","volume":"100","author":"Amin","year":"2020","journal-title":"Acta Dermato-Venereol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jaad.2016.07.064","article-title":"Psoriasis and comorbid diseases: Epidemiology","volume":"76","author":"Takeshita","year":"2017","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"880201","DOI":"10.3389\/fimmu.2022.880201","article-title":"Epidemiology of Psoriasis and Comorbid Diseases: A Narrative Review","volume":"13","author":"Bu","year":"2022","journal-title":"Front. Immunol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"401","DOI":"10.24869\/psyd.2017.401","article-title":"Analysis of the Prevalence of Mental Disorders in Psoriasis: The Relevance of Psychiatric Assessment in Dermatology","volume":"29","author":"Ferreira","year":"2017","journal-title":"Psychiatr. Danub."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1038\/jid.2013.508","article-title":"The prevalence and odds of depressive symptoms and clinical depression in psoriasis patients: A systematic review and meta-analysis","volume":"134","author":"Dowlatshahi","year":"2014","journal-title":"J. Investig. Dermatol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.pnpbp.2017.05.023","article-title":"Neurodevelopmental theory of depression","volume":"80","author":"Talarowska","year":"2018","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"201","DOI":"10.2147\/DDDT.S32713","article-title":"New developments in the management of psoriasis and psoriatic arthritis: A focus on apremilast","volume":"7","author":"Palfreeman","year":"2013","journal-title":"Drug Des. Dev. Ther."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.cyto.2014.12.014","article-title":"Cytokines in psoriasis","volume":"73","author":"Baliwag","year":"2015","journal-title":"Cytokine"},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Vi\u010di\u0107, M., Ka\u0161telan, M., Brajac, I., Soto\u0161ek, V., and Massari, L.P. (2021). Current Concepts of Psoriasis Immunopathogenesis. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms222111574"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.genhosppsych.2022.01.006","article-title":"Associations between psoriasis and mental illness: An update for clinicians","volume":"75","author":"Hedemann","year":"2022","journal-title":"Gen. Hosp. Psychiatry"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Marek-Jozefowicz, L., Czajkowski, R., Borkowska, A., Nedoszytko, B., \u017bmijewski, M.A., Cuba\u0142a, W.J., and Slominski, A.T. (2022). The Brain\u2013Skin Axis in Psoriasis\u2014Psychological, Psychiatric, Hormonal, and Dermatological Aspects. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23020669"},{"key":"ref_22","first-page":"e9708","article-title":"Association between Psoriasis and Depression: A Traditional Review","volume":"12","author":"Sahi","year":"2020","journal-title":"Cureus"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1159\/000450826","article-title":"Systematic Review of Health-Related Quality of Life in Adolescents with Psoriasis","volume":"232","author":"Gonzalez","year":"2017","journal-title":"Dermatology"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"5823684","DOI":"10.1155\/2018\/5823684","article-title":"The Pathophysiological Mechanisms and the Quest for Biomarkers in Psoriasis, a Stress-Related Skin Disease","volume":"2018","author":"Tampa","year":"2018","journal-title":"Dis. Markers"},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Kalkman, H.O. (2019). Novel Treatment Targets Based on Insights in the Etiology of Depression: Role of IL-6 Trans-Signaling and Stress-Induced Elevation of Glutamate and ATP. Pharmaceuticals, 12.","DOI":"10.3390\/ph12030113"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1159\/000448122","article-title":"Major Depression and Psoriasis: A Psychodermatological Phenomenon","volume":"29","author":"Tohid","year":"2016","journal-title":"Ski. Pharmacol. Physiol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s00403-012-1303-8","article-title":"The expression of serotonin transporter protein correlates with the severity of psoriasis and chronic stress","volume":"305","author":"Thorslund","year":"2013","journal-title":"Arch. Dermatol. Res."},{"key":"ref_28","first-page":"21","article-title":"Some psychosomatic aspects of psoriasis","volume":"5","author":"Gupta","year":"1990","journal-title":"Adv. Dermatol."},{"key":"ref_29","first-page":"42","article-title":"Psychodermatologia w codziennej praktyce lekarskiej","volume":"01","year":"2021","journal-title":"Dermatol. Po Dyplomie"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"897","DOI":"10.2340\/00015555-2702","article-title":"Antidepressants have Anti-inflammatory Effects that may be Relevant to Dermatology: A Systematic Review","volume":"97","author":"Eskeland","year":"2017","journal-title":"Acta Dermato-Venereol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1111\/joim.12093","article-title":"Use of serotonin reuptake inhibitors in patients with psoriasis is associated with a decreased need for systemic psoriasis treatment: A population-based cohort study","volume":"274","author":"Thorslund","year":"2013","journal-title":"J. Intern. Med."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s40744-020-00207-6","article-title":"Depression in Psoriatic Arthritis: Dimensional Aspects and Link with Systemic Inflammation","volume":"7","author":"Mathew","year":"2020","journal-title":"Rheumatol. Ther."},{"key":"ref_33","unstructured":"Roman, N.J., and S\u0142awomir, M. (2022). Dermatologia i Choroby Przenoszone Drog\u0105 P\u0142ciow\u0105, PZWL."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1097\/DER.0000000000000161","article-title":"Burden of Sleep and Fatigue in US Adults with Atopic Dermatitis","volume":"27","author":"Yu","year":"2016","journal-title":"Dermatitis"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/cod.12786","article-title":"Hand eczema, atopic dermatitis and filaggrin mutations in adult Danes: A registry-based study assessing risk of disability pension","volume":"77","author":"Heede","year":"2017","journal-title":"Contact Dermat."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Lee, S., and Shin, A. (2017). Association of atopic dermatitis with depressive symptoms and suicidal behaviors among adolescents in Korea: The 2013 Korean Youth Risk Behavior Survey. BMC Psychiatry, 17.","DOI":"10.1186\/s12888-016-1160-7"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1136\/jnnp-2011-301779","article-title":"Depression: An inflammatory illness?","volume":"83","author":"Krishnadas","year":"2012","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1111\/all.13231","article-title":"Atopic dermatitis is associated with anxiety, depression, and suicidal ideation, but not with psychiatric hospitalization or suicide","volume":"73","author":"Thyssen","year":"2018","journal-title":"Allergy"},{"key":"ref_39","first-page":"925","article-title":"IL-4 and IL-13 Inhibition in Atopic Dermatitis","volume":"15","author":"Matsunaga","year":"2016","journal-title":"J. Drugs Dermatol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1080\/17512433.2018.1449642","article-title":"Dupilumab for treatment of atopic dermatitis","volume":"11","author":"Srour","year":"2018","journal-title":"Expert Rev. Clin. Pharmacol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1080\/09546634.2019.1612836","article-title":"Dupilumab improves patient-reported symptoms of atopic dermatitis, symptoms of anxiety and depression, and health-related quality of life in moderate-to-severe atopic dermatitis: Analysis of pooled data from the randomized trials SOLO 1 and SOLO 2","volume":"31","author":"Cork","year":"2020","journal-title":"J. Dermatol. Treat."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1080\/09546634.2019.1630702","article-title":"Defining the role of mirtazapine in the treatment of refractory pruritus","volume":"32","author":"Fawaz","year":"2021","journal-title":"J. Dermatol. Treat."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1054898","DOI":"10.3389\/fmed.2022.1054898","article-title":"Anxiety, depression, and quality of life in children and adults with alopecia areata: A systematic review and meta-analysis","volume":"9","author":"Muller","year":"2022","journal-title":"Front. Med."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.jaad.2020.06.047","article-title":"Psychosocial and psychiatric comorbidities and health-related quality of life in alopecia areata: A systematic review","volume":"85","author":"Toussi","year":"2021","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1001\/jamadermatol.2022.6085","article-title":"Prevalence and Odds of Depressive and Anxiety Disorders and Symptoms in Children and Adults with Alopecia Areata: A Systematic Review and Meta-analysis","volume":"159","author":"Lauron","year":"2023","journal-title":"JAMA Dermatol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1001\/jamadermatol.2021.2196","article-title":"Health-Related Quality of Life, Depression, and Self-esteem in Patients with Androgenetic Alopecia: A Systematic Review and Meta-analysis","volume":"157","author":"Huang","year":"2021","journal-title":"JAMA Dermatol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1001\/jamadermatol.2018.4398","article-title":"Assessment of a Bidirectional Association Between Major Depressive Disorder and Alopecia Areata","volume":"155","author":"Vallerand","year":"2019","journal-title":"JAMA Dermatol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1016\/j.jaad.2019.11.064","article-title":"Bidirectional association between alopecia areata and major depressive disorder among probands and unaffected siblings: A nationwide population-based study","volume":"82","author":"Dai","year":"2020","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_49","first-page":"130","article-title":"Alopecia areata is characterized by dysregulation in systemic type 17 and type 2 cytokines, which may contribute to disease-associated psychological morbidity","volume":"182","author":"Bain","year":"2020","journal-title":"Br. J. Dermatol."},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Younes, A.-K., Hammad, R., Othman, M., and Sobhy, A. (2022). CD4, CD8 and natural killer cells are depressed in patients with alopecia areata: Their association with disease activity. BMC Immunol., 23.","DOI":"10.1186\/s12865-022-00486-4"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1111\/bjd.16808","article-title":"Alopecia areata: A review of disease pathogenesis","volume":"179","author":"Rajabi","year":"2018","journal-title":"Br. J. Dermatol."},{"key":"ref_52","first-page":"1417","article-title":"Lichen planus is associated with depression and anxiety: A cross-sectional study in the All of Us research program","volume":"315","author":"Hong","year":"2023","journal-title":"Arch. Dermatol. Res."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.jad.2021.12.127","article-title":"Risk of anxiety and depression in patients with lichen planus: A nationwide population-based study","volume":"300","author":"Hsu","year":"2022","journal-title":"J. Affect. Disord."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"adv00330","DOI":"10.2340\/00015555-3660","article-title":"Prevalence and Odds of Signs of Depression and Anxiety in Patients with Lichen Planus: Systematic Review and Meta-analyses","volume":"100","author":"Jalenques","year":"2020","journal-title":"Acta Dermato-Venereol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"adv00619","DOI":"10.2340\/actadv.v101.442","article-title":"Quality of Life and Psychopathology in Lichen Planus: A Neglected Disease Burden","volume":"101","author":"Fiocco","year":"2021","journal-title":"Acta Dermato-Venereol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1007\/s00784-021-04114-0","article-title":"Depression, anxiety, and stress in oral lichen planus: A systematic review and meta-analysis","volume":"26","author":"Warnakulasuriya","year":"2022","journal-title":"Clin. Oral Investig."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1111\/odi.12423","article-title":"Psychological disorders and oral lichen planus: Matched case\u2013control study and literature review","volume":"22","author":"Pippi","year":"2016","journal-title":"Oral Dis."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1111\/odi.13569","article-title":"Anxiety and oral lichen planus","volume":"27","author":"Liao","year":"2021","journal-title":"Oral Dis."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"391","DOI":"10.2334\/josnusd.18-0113","article-title":"Evaluation of depression, anxiety and stress levels in patients with oral lichen planus","volume":"61","author":"Manczyk","year":"2019","journal-title":"J. Oral Sci."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/adj.12896","article-title":"Characteristics of the psychopathological status of oral lichen planus: A systematic review and meta-analysis","volume":"67","author":"Li","year":"2022","journal-title":"Aust. Dent. J."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"146","DOI":"10.5021\/ad.2019.31.2.146","article-title":"Serotonin Expression in Lichen Planus Lesions and Its Relationship with Depression\/Anxiety","volume":"31","author":"Canpolat","year":"2019","journal-title":"Ann. Dermatol."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.bbr.2016.11.047","article-title":"Using the BITOLA system to identify candidate molecules in the interaction between oral lichen planus and depression","volume":"320","author":"Zhan","year":"2017","journal-title":"Behav. Brain Res."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1111\/odi.14081","article-title":"Psychological profile and \u03b1-amylase levels in oral lichen planus patients: A case\u2013control preliminary study","volume":"29","author":"Pires","year":"2023","journal-title":"Oral Dis."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"156","DOI":"10.4103\/0973-029X.119741","article-title":"Triology of nitric oxide, mast cell and stress in pathogenesis of oral lichen planus","volume":"17","author":"Kapoor","year":"2013","journal-title":"J. Oral Maxillofac. Pathol."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.psym.2012.09.004","article-title":"Depressive symptoms and associated factors in systemic lupus erythematosus: A systematic review","volume":"54","author":"Karol","year":"2013","journal-title":"Psychosomatics"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1177\/09612033231173510","article-title":"Depression and anxiety in systemic lupus erythematosus: A case-control study on prevalence and associated factors in a single-center cohort","volume":"32","author":"Erausquin","year":"2023","journal-title":"Lupus"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"e689","DOI":"10.1002\/iid3.689","article-title":"Anxiety and depression prevalence and their risk factors in lupus nephritis patients: A case\u2013control study","volume":"10","author":"Hu","year":"2022","journal-title":"Immunity, Inflamm. Dis."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"2829018","DOI":"10.1155\/2016\/2829018","article-title":"Depressive and Anxiety Disorders in Systemic Lupus Erythematosus Patients without Major Neuropsychiatric Manifestations","volume":"2016","author":"Bai","year":"2016","journal-title":"J. Immunol. Res."},{"key":"ref_69","doi-asserted-by":"crossref","unstructured":"Zehravi, M., Kabir, J., Akter, R., Malik, S., Ashraf, G.M., Tagde, P., Ramproshad, S., Mondal, B., Rahman, H., and Mohan, A.G. (2022). A Prospective Viewpoint on Neurological Diseases and Their Biomarkers. Molecules, 27.","DOI":"10.3390\/molecules27113516"},{"key":"ref_70","first-page":"993","article-title":"Psychiatric Symptoms in Systemic Lupus Erythematosus","volume":"73","author":"Meszaros","year":"2012","journal-title":"Br. J. Psychol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.jpsychores.2019.05.002","article-title":"Associations between resilience and sociodemographic factors and depressive symptoms in women with systemic lupus erythematosus","volume":"122","year":"2019","journal-title":"J. Psychosom. Res."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"2074","DOI":"10.1136\/ard.2010.130476","article-title":"EULAR Recommendations for the Management of Systemic Lupus Erythematosus with Neuropsychiatric Manifestations: Report of a Task Force of the EULAR Standing Committee for Clinical Affairs","volume":"69","author":"Bertsias","year":"2010","journal-title":"Ann. Rheum. Dis."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"34","DOI":"10.55563\/clinexprheumatol\/qo1ehz","article-title":"The Hospital Anxiety and Depression Scale in patients with systemic sclerosis: A psychometric and factor analysis in a monocentric cohort","volume":"39","author":"Garaiman","year":"2021","journal-title":"Clin. Exp. Rheumatol."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.jad.2018.09.075","article-title":"The burden of depression in systemic sclerosis patients: A nationwide population-based study","volume":"243","author":"Bragazzi","year":"2019","journal-title":"J. Affect. Disord."},{"key":"ref_75","first-page":"S242","article-title":"Sleep Disturbance in Scleroderma","volume":"27","author":"Figueiredo","year":"2020","journal-title":"Am. J. Clin. Oncol."},{"key":"ref_76","first-page":"30","article-title":"Comparative analysis of anxiety-depressive spectrum disorders in patients with rheumatic diseases","volume":"90","author":"Lisitsyna","year":"2018","journal-title":"Ter. Arkh."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"e13418","DOI":"10.1111\/dth.13418","article-title":"Psychodermatology of vitiligo: Psychological impact and consequences","volume":"33","author":"Simons","year":"2020","journal-title":"Dermatol. Ther."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1111\/jdv.14739","article-title":"The prevalence and odds of depression in patients with vitiligo: A meta-analysis","volume":"32","author":"Wang","year":"2018","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1111\/bjd.15199","article-title":"Vitiligo and depression: A systematic review and meta-analysis of observational studies","volume":"177","author":"Lai","year":"2017","journal-title":"Br. J. Dermatol."},{"key":"ref_80","first-page":"11","article-title":"A Systematic Review on Prevalence and Assessment of Sexual Dysfunction in Vitiligo","volume":"70","author":"Saikarthik","year":"2022","journal-title":"J. Assoc. Physicians India"},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1007\/s40257-021-00631-6","article-title":"Psychosocial Effects of Vitiligo: A Systematic Literature Review","volume":"22","author":"Ezzedine","year":"2021","journal-title":"Am. J. Clin. Dermatol."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.biocel.2018.09.007","article-title":"Human \u03b2-defensin 1 update: Potential clinical applications of the restless warrior","volume":"104","year":"2018","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1080\/13548506.2017.1339895","article-title":"Depression in primary Sj\u00f6gren\u2019s syndrome: A systematic review and meta-analysis","volume":"23","author":"Cui","year":"2018","journal-title":"Psychol. Health Med."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"647","DOI":"10.55563\/clinexprheumatol\/nspi47","article-title":"Research Progress on the Pathogenesis and Quality of Life of Patients with Primary Sj\u00f6gren\u2019s Syndrome Complicated by Depression","volume":"40","author":"Huang","year":"2022","journal-title":"Clin. Exp. Rheumatol."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"437","DOI":"10.12740\/PP\/76863","article-title":"Inflammatory Theory of Depression","volume":"52","author":"Galecki","year":"2018","journal-title":"Psychiatr. Polska"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.neuron.2020.06.002","article-title":"The Bidirectional Relationship of Depression and Inflammation: Double Trouble","volume":"107","author":"Beurel","year":"2020","journal-title":"Neuron"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/neu.2016.69","article-title":"Inflammation and depression: A causal or coincidental link to the pathophysiology?","volume":"30","author":"Leonard","year":"2018","journal-title":"Acta Neuropsychiatr."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1177\/00048674211031486","article-title":"Dietary patterns and internalizing symptoms in children and adolescents: A meta-analysis","volume":"56","author":"Orlando","year":"2022","journal-title":"Aust. N. Z. J. Psychiatry"},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1007\/s43440-020-00202-2","article-title":"Update on the neurodevelopmental theory of depression: Is there any \u2018Unconscious Code\u2019?","volume":"73","author":"Galecka","year":"2021","journal-title":"Pharmacol. Rep."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/j.pharep.2019.05.022","article-title":"An immune gate of depression\u2014Early neuroimmune development in the formation of the underlying depressive disorder","volume":"71","author":"Kowalczyk","year":"2019","journal-title":"Pharmacol. Rep."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/11\/3224\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T14:50:56Z","timestamp":1760107856000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/11\/3224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,30]]},"references-count":90,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2024,6]]}},"alternative-id":["jcm13113224"],"URL":"https:\/\/doi.org\/10.3390\/jcm13113224","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,30]]}}}