{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T22:43:09Z","timestamp":1789512189165,"version":"build-2803163510"},"reference-count":44,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T00:00:00Z","timestamp":1717718400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Objectives: The aim of this study was to evaluate the functional outcomes and balance compensation in patients with severe Meniere\u2019s disease after vestibular neurectomy. Methods: Pre- and postoperative results were analyzed in twenty patients with unilateral Meniere\u2019s disease before and two years after vestibular neurectomy. Clinical evaluation was performed using a subjective grading scale proposed by the American Academy of Otolaryngology-Head and Neck Surgery and the Dizziness Handicap Inventory. Sensory organization test results were analyzed to assess the balance system before and after the surgery. Results: All patients reported a complete resolution of vertigo attacks after the vestibular neurectomy; 95% of patients reported functional level improvement according to a scale proposed by the American Academy of Otolaryngology-Head and Neck Surgery, and the average score decreased from 4.5 to 1.6. Clinical improvement, evaluated with the Dizziness Handicap Inventory, was present in all patients, with the average result decreasing from 81.7 to 16.4. Analyzing both grading systems, differences between pre- and postoperative results were statistically significant. No statistically significant differences were found between the sensory organization test results before and after vestibular neurectomy. Significant correlations were found between a patient\u2019s age and postoperative results of the Dizziness Handicap Inventory and posturography. Conclusions: Vestibular neurectomy is an effective vertigo treatment in patients with severe Meniere\u2019s disease with no clinical improvement despite conservative treatment. It results in subjective physical, functional, and emotional improvement, enabling patients to return to daily activities and work. An appropriate qualification of patients and comprehensive preoperative evaluation are essential to obtaining satisfactory clinical outcomes.<\/jats:p>","DOI":"10.3390\/jcm13123362","type":"journal-article","created":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T08:05:17Z","timestamp":1717747517000},"page":"3362","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Functional Level and Dynamic Posturography Results Two Years after Vestibular Neurectomy in Patients with Severe Meniere\u2019s Disease"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7665-409X","authenticated-orcid":false,"given":"Agnieszka","family":"Jasi\u0144ska-Nowacka","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery, Medical University of Warsaw, Banacha 1a Str., 02-097 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3631-2551","authenticated-orcid":false,"given":"Magdalena","family":"Lachowska","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery, Medical University of Warsaw, Banacha 1a Str., 02-097 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazimierz","family":"Niemczyk","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery, Medical University of Warsaw, Banacha 1a Str., 02-097 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,7]]},"reference":[{"key":"ref_1","first-page":"239","article-title":"Sur une forme de surdit\u00e9 grave d\u00e9pendant d\u2019une l\u00e9sion de l\u2019oreille interne","volume":"16","author":"Meniere","year":"1861","journal-title":"Gaz. Med. Paris"},{"key":"ref_2","first-page":"77","article-title":"Meniere\u2019s Disease","volume":"82","author":"Gibson","year":"2019","journal-title":"Adv. Otorhinolaryngol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/S0140-6736(08)61161-7","article-title":"Meniere\u2019s disease","volume":"372","author":"Sajjadi","year":"2008","journal-title":"Lancet"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S0030-6665(02)00019-1","article-title":"Etiology, pathophysiology of symptoms, and pathogenesis of Meniere\u2019s disease","volume":"35","author":"Paparella","year":"2002","journal-title":"Otolaryngol. Clin. N. Am."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"S71","DOI":"10.1007\/s00415-015-7930-1","article-title":"What is Meniere\u2019s disease? A contemporary re-evaluation of endolymphatic hydrops","volume":"263","author":"Gurkov","year":"2016","journal-title":"J. Neurol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"2445","DOI":"10.4103\/0366-6999.191767","article-title":"Characteristics of the Cochlear Symptoms and Functions in Meniere\u2019s Disease","volume":"129","author":"Zhang","year":"2016","journal-title":"Chin. Med. J."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"23","DOI":"10.5604\/01.3001.0016.2701","article-title":"Detailed clinical characteristics and its correlation with the diagnostic test results in patients with defined M\u00e9ni\u00e8re\u2019s disease","volume":"77","author":"Lachowska","year":"2023","journal-title":"Otolaryngol. Pol."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Committee on Hearing and Equilibrium (1995). Committee on Hearing and Equilibrium guidelines for the diagnosis and evaluation of therapy in Meniere\u2019s disease. Otolaryngol. Head Neck Surg., 113, 181\u2013185.","DOI":"10.1016\/S0194-5998(95)70102-8"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.otorri.2015.05.005","article-title":"Diagnostic criteria for Meniere\u2019s disease. Consensus document of the Barany Society, the Japan Society for Equilibrium Research, the European Academy of Otology and Neurotology (EAONO), the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) and the Korean Balance Society","volume":"67","author":"Carey","year":"2016","journal-title":"Acta Otorrinolaringol. Esp."},{"key":"ref_10","first-page":"S1","article-title":"Clinical Practice Guideline: Meniere\u2019s Disease","volume":"162","author":"Basura","year":"2020","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"S29","DOI":"10.1016\/j.anorl.2017.12.006","article-title":"International consensus (ICON) on treatment of Meniere\u2019s disease","volume":"135","author":"Nevoux","year":"2018","journal-title":"Eur. Ann. Otorhinolaryngol. Head Neck Dis."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.anorl.2016.12.003","article-title":"Diagnostic and therapeutic strategy in Meniere\u2019s disease. Guidelines of the French Otorhinolaryngology-Head and Neck Surgery Society (SFORL)","volume":"134","author":"Nevoux","year":"2017","journal-title":"Eur. Ann. Otorhinolaryngol. Head Neck Dis."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"317","DOI":"10.5152\/iao.2018.140818","article-title":"European Position Statement on Diagnosis, and Treatment of Meniere\u2019s Disease","volume":"14","author":"Magnan","year":"2018","journal-title":"J. Int. Adv. Otol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1007\/s00405-019-05423-7","article-title":"Therapeutic strategies in the treatment of Meniere\u2019s disease: The Italian experience","volume":"276","author":"Quaranta","year":"2019","journal-title":"Eur. Arch. Oto-Rhino-Laryngol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"18","DOI":"10.5604\/01.3001.0014.0305","article-title":"M\u00e9ni\u00e8re\u2019s disease pt. 2. Treatment options and therapeutic strategies. Commentary to the current recommendations and own experience","volume":"9","author":"Niemczyk","year":"2020","journal-title":"Pol. Otorhinolaryngol. Rev."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"103565","DOI":"10.1016\/j.amjoto.2022.103565","article-title":"Prevalence of anxiety and depression in Meniere\u2019s disease; a comparative analytical study","volume":"43","author":"Lahiji","year":"2022","journal-title":"Am. J. Otolaryngol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1017\/S002221512000081X","article-title":"Depression in Meniere\u2019s disease: A systematic review and meta-analysis","volume":"134","author":"Patel","year":"2020","journal-title":"J. Laryngol. Otol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1111\/1467-9566.12527","article-title":"A day in the life of a Meniere\u2019s patient: Understanding the lived experiences and mental health impacts of Meniere\u2019s disease","volume":"39","author":"Bell","year":"2017","journal-title":"Sociol. Health Illn."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1097\/MAO.0000000000000732","article-title":"Mental Health and Subjective Well-being of Individuals With Meniere\u2019s: Cross-sectional Analysis in the UK Biobank","volume":"36","author":"Tyrrell","year":"2015","journal-title":"Otol. Neurotol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1097\/00129492-200107000-00020","article-title":"Patients\u2019 subjective evaluations of quality of life related to disease-specific symptoms, sense of coherence, and treatment in Meniere\u2019s disease","volume":"22","author":"Soderman","year":"2001","journal-title":"Otol. Neurotol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S0030-6665(20)32323-9","article-title":"Staging Meniere\u2019s disease (or any inner ear dysfunction) and the use of the vertigogram","volume":"13","author":"Arenberg","year":"1980","journal-title":"Otolaryngol. Clin. N. Am."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1097\/00005537-199709000-00009","article-title":"Vestibular nerve section: Long-term follow-up","volume":"107","author":"Pappas","year":"1997","journal-title":"Laryngoscope"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1001\/archotol.1990.01870040046011","article-title":"The development of the Dizziness Handicap Inventory","volume":"116","author":"Jacobson","year":"1990","journal-title":"Arch. Otolaryngol. Head Neck Surg."},{"key":"ref_24","first-page":"529","article-title":"Validation of the Polish version of the Dizziness Handicap Inventory","volume":"70","year":"2019","journal-title":"Med. Pracy"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1097\/AUD.0000000000001405","article-title":"Item Level Psychometrics of the Dizziness Handicap Inventory in Vestibular Migraine and Meniere\u2019s Disease","volume":"45","author":"Rizk","year":"2024","journal-title":"Ear Hear."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1177\/019459988008800430","article-title":"Middle fossa vestibular neurectomy: A report of 373 cases","volume":"88","year":"1980","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.anl.2009.06.006","article-title":"Vestibular function outcomes after vestibular neurectomy in Meniere disease: Can vestibular neurectomy provide complete vestibular deafferentation?","volume":"37","author":"Leveque","year":"2010","journal-title":"Auris Nasus Larynx"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.neuchi.2018.11.002","article-title":"Postoperative compensation after neurotomy in Meniere\u2019s disease: Retrospective study of 15 cases","volume":"65","author":"Lemnos","year":"2019","journal-title":"Neurochirurgie"},{"key":"ref_29","first-page":"23","article-title":"Vestibular neurectomy in the United States\u20141990","volume":"13","author":"Silverstein","year":"1992","journal-title":"Am. J. Otol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1097\/MAO.0b013e318268d1cd","article-title":"Functional results and quality of life after retrosigmoid vestibular neurectomy in patients with Meniere\u2019s disease","volume":"33","author":"Schlegel","year":"2012","journal-title":"Otol. Neurotol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1017\/S0022215100142719","article-title":"Long-term results of vestibular nerve section","volume":"112","author":"Tewary","year":"1998","journal-title":"J. Laryngol. Otol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0385-8146(00)00076-6","article-title":"Vestibular neurectomy","volume":"27","author":"Thomsen","year":"2000","journal-title":"Auris Nasus Larynx"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.3171\/2021.10.JNS21145","article-title":"Long-term efficacy of vestibular neurotomy in disabling Meniere\u2019s disease and Tumarkin drop attacks","volume":"137","author":"Brenet","year":"2022","journal-title":"J. Neurosurg."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.anl.2021.12.001","article-title":"Changes in endolymphatic hydrops after vestibular neurectomy observed in magnetic resonance imaging\u2014A pilot study","volume":"49","author":"Lachowska","year":"2022","journal-title":"Auris Nasus Larynx"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1097\/00005537-199612000-00022","article-title":"The outcome of vestibular nerve section for intractable vertigo: The patient\u2019s point of view","volume":"106","author":"Reid","year":"1996","journal-title":"Laryngoscope"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.anl.2023.11.009","article-title":"Vestibular compensation: Neural mechanisms and clinical implications for the treatment of vertigo","volume":"51","author":"Takeda","year":"2023","journal-title":"Auris Nasus Larynx."},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Esteban-Sanchez, J., and Martin-Sanz, E. (2022). Long-Term Evolution of Vestibular Compensation, Postural Control, and Perceived Disability in a Population of Patients with Vestibular Neuritis. J. Clin. Med., 11.","DOI":"10.3390\/jcm11143941"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1177\/019459989110400104","article-title":"Vestibular compensation after labyrinthectomy and vestibular neurectomy in cats","volume":"104","author":"Cass","year":"1991","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1159\/000494965","article-title":"Measurements of Trunk Sway for Stance and Gait Tasks 2 Years after Vestibular Neurectomy","volume":"23","author":"Vibert","year":"2018","journal-title":"Audiol. Neurootol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.heares.2004.06.010","article-title":"The usefulness of computerized dynamic posturography for the study of equilibrium in patients with Meniere\u2019s disease: Correlation with clinical and audiologic data","volume":"196","author":"Soto","year":"2004","journal-title":"Hear. Res."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1080\/00016489.2017.1278790","article-title":"How minimally invasive vestibular neurotomy for incapacitating Meniere\u2019s disease improves dizziness and anxiety","volume":"137","author":"Miyazaki","year":"2017","journal-title":"Acta Otolaryngol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1136\/jnnp.2009.171983","article-title":"Long-term effects of vestibular compensation on balance control and sensory organisation after unilateral deafferentation due to vestibular schwannoma surgery","volume":"81","author":"Gauchard","year":"2010","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.neuroscience.2010.10.059","article-title":"Pre-operative vestibular pattern and balance compensation after vestibular schwannoma surgery","volume":"172","author":"Gauchard","year":"2011","journal-title":"Neuroscience"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1007\/s00415-018-8834-7","article-title":"The Dizziness Handicap Inventory does not correlate with vestibular function tests: A prospective study","volume":"265","author":"Yip","year":"2018","journal-title":"J. Neurol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/12\/3362\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T14:55:12Z","timestamp":1760108112000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/12\/3362"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,7]]},"references-count":44,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,6]]}},"alternative-id":["jcm13123362"],"URL":"https:\/\/doi.org\/10.3390\/jcm13123362","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,7]]}}}