{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T15:22:24Z","timestamp":1780672944547,"version":"3.54.1"},"reference-count":37,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2024,6,29]],"date-time":"2024-06-29T00:00:00Z","timestamp":1719619200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Nicolaus Copernicus University"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: To evaluate functional and anatomical outcomesof cataract surgery in neovascular age-related macular neovascularization (nAMD) eyes receiving anti-vascular endothelial growth factor (anti-VEGF) intravitreal injections in modified pro re nata (PRN) regimen. Materials and Methods: Sixty eyes of 60 nAMD patients, including 41 women (68.3%) and 19 men (31.7%) in an average age of 77.35 \u00b1 6.41 years, under treatment with intravitreal aflibercept injections in modified PRN regimen with no signs of macular neovascularization (MNV) activity during two consecutive visits were included in this prospective, observational study. Best-corrected visual acuity (BCVA), central retinal thickness (CRT), as well as the number of anti-VEGF injections were monitored six months before and after phacoemulsification with intraocular lens (IOL) implantation. Further, the change of the abovementioned parameters was assessed during the six-month follow-up period for CRT and the number of injections, while the BCVA was monitored for 54 months. Results: BCVA measured on the first day after surgery (0.17 \u00b1 0.19 logMAR) as well as in the six-month post-surgery (0.13 \u00b1 0.16 logMAR) significantly improved compared to preop values (0.42 \u00b1 0.20 logMAR). BCVA remains stable during the observational period. We found that both differences were statistically significant (p &lt; 0.01). The mean CRT and the mean number of injections did not differ between the six-month pre- and post-surgical periods. Conclusions: We showed the beneficial effect of phacoemulsification in nAMD patients treated with anti-VEGF agents on visual outcomes in the short and long term. Cataract surgery in nAMD eyes treated with anti-VEGF injections does not increase the frequency of anti-VEGF injections and does not cause deterioration of the macular status.<\/jats:p>","DOI":"10.3390\/jcm13133832","type":"journal-article","created":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T09:06:07Z","timestamp":1719824767000},"page":"3832","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Cataract Surgery in nAMD Patients Receiving Intravitreal Aflibercept Injections"],"prefix":"10.3390","volume":"13","author":[{"given":"Ma\u0142gorzata","family":"Seredyka-Burduk","sequence":"first","affiliation":[{"name":"Division of Ophthalmology and Optometry, Department of Ophthalmology, Collegium Medicum, Nicolaus Copernicus University, Kornela Ujejskiego 75 Street, 85-168 Bydgoszcz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6942-2506","authenticated-orcid":false,"given":"Slawomir","family":"Liberski","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Poznan University of Medical Sciences, Augustyna Szamarzewskiego 84 Street, 61-848 Pozna\u0144, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gra\u017cyna","family":"Malukiewicz","sequence":"additional","affiliation":[{"name":"Division of Ophthalmology and Optometry, Department of Ophthalmology, Collegium Medicum, Nicolaus Copernicus University, Kornela Ujejskiego 75 Street, 85-168 Bydgoszcz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaros\u0142aw","family":"Koci\u0119cki","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Poznan University of Medical Sciences, Augustyna Szamarzewskiego 84 Street, 61-848 Pozna\u0144, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1332-3592","authenticated-orcid":false,"given":"Bartlomiej J.","family":"Kaluzny","sequence":"additional","affiliation":[{"name":"Division of Ophthalmology and Optometry, Department of Ophthalmology, Collegium Medicum, Nicolaus Copernicus University, Kornela Ujejskiego 75 Street, 85-168 Bydgoszcz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,29]]},"reference":[{"key":"ref_1","first-page":"364","article-title":"Visual Impairment and Quality of Life Among Older Adults: An Examination of Explanations for the Relationship","volume":"66","author":"Brown","year":"2011","journal-title":"Gerontol. 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