{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:16:02Z","timestamp":1760145362698,"version":"build-2065373602"},"reference-count":28,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2024,7,7]],"date-time":"2024-07-07T00:00:00Z","timestamp":1720310400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/objectives: The aim of this study was to evaluate the long-term outcomes of a cohort of ophthalmologically resolved female idiopathic intracranial hypertension (IIH) patients. Methods: Our cross-sectional study included adult females with at least 6 months of ophthalmologically resolved IIH. Patients with papilledema or who underwent IIH-targeted surgical intervention were excluded. Participants completed a questionnaire consisting of medical information, the Migraine Disability Assessment Scale (MIDAS) and the Headache Impact Test (HIT-6). Electronic medical records and the results of imaging upon diagnosis were retrospectively reviewed. Results: One-hundred-and-four participants (mean age 35.5 \u00b1 11.9 years) were included (7.85 \u00b1 7 years post-IIH diagnosis). Patients with moderate\u2013severe disability according to the MIDAS scale (n = 68, 65.4%) were younger (32.4 \u00b1 8.9 vs. 41.5 \u00b1 14.4 year-old, p &lt; 0.001), had a shorter time interval from IIH diagnosis (5.9 \u00b1 5.3 vs. 11.7 \u00b1 8.5 years, p &lt; 0.001), and had lower FARB scores (indicating a more narrowed transverse-sigmoid junction; 1.28 \u00b1 1.82 vs. 2.47 \u00b1 2.3, p = 0.02) in comparison to patients with low\u2013mild disability scores. In multivariate analysis, a lower FARB score (OR 1.28, 95% CI 0.89\u20131.75, p = 0.12) and younger age (OR 1.09, 95% CI 0.98\u20131.19, p = 0.13) showed a trend toward an association with a moderate\u2013severe MIDAS score. Moreover, in the sub-analysis of patients with a moderate\u2013severe MIDAS scale score, the 10 patients with the highest MIDAS scores had a low FARB score (1.6 \u00b1 1.1 vs. 2.7 \u00b1 2.4, p = 0.041). Conclusions: High numbers of patients with ophthalmologically resolved IIH continue to suffer from related symptoms. Symptoms may be associated with the length of time from the diagnosis of IIH and a lower FARB score.<\/jats:p>","DOI":"10.3390\/jcm13133971","type":"journal-article","created":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T09:01:19Z","timestamp":1720429279000},"page":"3971","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Predictors of Headaches and Quality of Life in Women with Ophthalmologically Resolved Idiopathic Intracranial Hypertension"],"prefix":"10.3390","volume":"13","author":[{"given":"Anat","family":"Horev","sequence":"first","affiliation":[{"name":"Department of Neurology, Soroka University Medical Center, Beer Sheva 8453227, Israel"},{"name":"Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 8453227, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sapir","family":"Aharoni-Bar","sequence":"additional","affiliation":[{"name":"Ben-Gurion Medical School, Soroka University Medical Center, Beer Sheva 8453227, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Katson","sequence":"additional","affiliation":[{"name":"Rambam Health Care Campus, Haifa 3109601, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8148-6561","authenticated-orcid":false,"given":"Erez","family":"Tsumi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Soroka University Medical Center, Beer Sheva 8453227, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamir","family":"Regev","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Soroka University Medical Center, Beer Sheva 8453227, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yair","family":"Zlotnik","sequence":"additional","affiliation":[{"name":"Department of Neurology, Soroka University Medical Center, Beer Sheva 8453227, Israel"},{"name":"Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 8453227, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2244-297X","authenticated-orcid":false,"given":"Ron","family":"Biederko","sequence":"additional","affiliation":[{"name":"Clinical Research Center, Soroka University Medical Center, Beer Sheva 8453227, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gal","family":"Ifergane","sequence":"additional","affiliation":[{"name":"Department of Neurology, Soroka University Medical Center, Beer Sheva 8453227, Israel"},{"name":"Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 8453227, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilan","family":"Shelef","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 8453227, Israel"},{"name":"Department of Radiology, Soroka University Medical Center, Beer Sheva 8453227, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0160-8205","authenticated-orcid":false,"given":"Tal","family":"Eliav","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Jefferson Einstein Philadelphia Hospital, Philadelphia, PA 19141, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gal","family":"Ben-Arie","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 8453227, Israel"},{"name":"Department of Radiology, Soroka University Medical Center, Beer Sheva 8453227, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9489-0133","authenticated-orcid":false,"given":"Asaf","family":"Honig","sequence":"additional","affiliation":[{"name":"Department of Neurology, Soroka University Medical Center, Beer Sheva 8453227, Israel"},{"name":"Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 8453227, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,7,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1212\/WNL.0b013e3182a55f17","article-title":"Revised diagnostic criteria for the pseudotumor cerebri syndrome in adults and children","volume":"81","author":"Friedman","year":"2013","journal-title":"Neurology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0733-8619(18)30304-9","article-title":"Idiopathic intracranial hypertension","volume":"9","author":"Wall","year":"1991","journal-title":"Neurol. 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