{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T23:36:00Z","timestamp":1783812960870,"version":"3.55.0"},"reference-count":49,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T00:00:00Z","timestamp":1722988800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: Oral lichen planus (OLP) is a chronic inflammatory autoimmune disease of the oral mucosa that affects between 0.5% and 2% of the general population. In the last decade, several studies have associated cardiovascular diseases (CVDs) with some inflammatory skin diseases such as oral lichen planus, demonstrating the presence of dyslipidemia in these pathologies. The objective of this work is to review whether patients with OLP show higher dyslipidemia and CRP levels compared to a healthy control population without OLP. Methods: Searches were carried out in Medline, Scopus, and Cochrane. The studies had to perform a histopathological diagnosis for OLP and the patients could not take any medication to treat this disorder. Non-lichenoid reactions were included. Results: After an initial search that provided us with 254 papers, this number was reduced to 10 articles after a detailed evaluation. All of them were case\u2013control studies that compared the presence of analytical cardiovascular risk factors in patients affected by OLP and in healthy subjects. Conclusions: There is no scientific evidence of the possible association between OLP and CVDs. The only association we can prove is the one between OPL and CVD risk factors, especially those related to the lipid profile. More studies are needed in order to evaluate this relationship in patients diagnosed with CVDs.<\/jats:p>","DOI":"10.3390\/jcm13164630","type":"journal-article","created":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T07:01:25Z","timestamp":1723100485000},"page":"4630","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Relationship between Oral Lichen Planus and Cardiovascular Disease of Atherosclerotic Origin: Systematic Review and Meta-Analysis"],"prefix":"10.3390","volume":"13","author":[{"given":"Beatriz","family":"Gonzalez Navarro","sequence":"first","affiliation":[{"name":"School of Dentistry, Oral Health and Masticatory System Group, (Bellvitge Biomedical Research Institute) IDIBELL, University of Barcelona, 08907 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Egido Moreno","sequence":"additional","affiliation":[{"name":"School of Dentistry, University of Barcelona, 08907 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Oma\u00f1a Cepeda","sequence":"additional","affiliation":[{"name":"School of Dentistry, University of Barcelona, 08907 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Estrugo Devesa","sequence":"additional","affiliation":[{"name":"School of Dentistry, Oral Health and Masticatory System Group, (Bellvitge Biomedical Research Institute) IDIBELL, University of Barcelona, 08907 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enric","family":"Jane Salas","sequence":"additional","affiliation":[{"name":"School of Dentistry, Oral Health and Masticatory System Group, (Bellvitge Biomedical Research Institute) IDIBELL, University of Barcelona, 08907 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8035-4412","authenticated-orcid":false,"given":"Jose","family":"Lopez Lopez","sequence":"additional","affiliation":[{"name":"School of Dentistry, Oral Health and Masticatory System Group, (Bellvitge Biomedical Research Institute) IDIBELL, University of Barcelona, 08907 Barcelona, Spain"},{"name":"Dental Hospital Barcelona University, Faculty of Medicine and Health Sciences (School of Dentistry), Campus Bellvitge, University of Barcelona, C\/Feixa LLaga s\/n, L\u2019Hospitalet de Llobregat, 08907 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,8,7]]},"reference":[{"key":"ref_1","first-page":"e938","article-title":"Oral lichen planus and its relationship with systemic diseases. 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