{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T21:42:21Z","timestamp":1789508541639,"version":"build-2803163510"},"reference-count":51,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2024,8,18]],"date-time":"2024-08-18T00:00:00Z","timestamp":1723939200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Victor Babes University of Medicine and Pharmacy Timisoara"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Congenital heart diseases (CHD) are one of the most common birth defects and the main leading cause of death in children. Many patients with CHD are reaching adulthood due to the success of improved contemporary surgical procedures. Understanding the etiology of CHD remains important for patient clinical management. Both genetic and environmental factors are involved in the development and progression of CHD. Variations in many different genes and chromosomal anomalies can be associated with CHD, by expression of different mechanisms. Sporadic cases are the most frequently encountered in these patients. Atrial septal defect is a common congenital heart disease that refers to direct communication between atrial chambers, found isolated or associated with other syndromes. Imaging techniques, especially transthoracic and transesophageal echocardiography (TOE) represent the key for diagnosis and management of ASD. The disease has a major incidence in adulthood, due to late symptomatology, but assessment and treatment are important to avoid time-related complications. Ebstein\u2019s anomaly is a rare congenital disease, with a dominant genetic participation, characterized by an abnormal displacement of the tricuspid valve and right ventricular myopathy, often requiring surgical intervention. Alongside echocardiography, cardiac magnetic resonance (CMR) imaging is the gold standard tool for the assessment of ventricular volumes. Early diagnosis and adequate treatment are mandatory to avoid possible complications of CHD, and thus, ECG, as well as imaging techniques, are important diagnostic tools. However, patients with CHD need a special healthcare team for the entire monitorization in various life stages.<\/jats:p>","DOI":"10.3390\/jcm13164865","type":"journal-article","created":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T06:41:31Z","timestamp":1724049691000},"page":"4865","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["From ECG to Imaging: Challenges in the Diagnosis of Adult Congenital Heart Diseases"],"prefix":"10.3390","volume":"13","author":[{"given":"Simina","family":"Cri\u0219an","sequence":"first","affiliation":[{"name":"Cardiology Department, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania"},{"name":"Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania"},{"name":"Research Center of the Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruxandra-Maria","family":"B\u0103ghin\u0103","sequence":"additional","affiliation":[{"name":"Cardiology Department, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania"},{"name":"Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania"},{"name":"Research Center of the Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Luca","sequence":"additional","affiliation":[{"name":"Cardiology Department, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania"},{"name":"Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania"},{"name":"Research Center of the Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oana","family":"P\u0103tru","sequence":"additional","affiliation":[{"name":"Cardiology Department, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania"},{"name":"Research Center of the Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihai-Andrei","family":"Laz\u0103r","sequence":"additional","affiliation":[{"name":"Cardiology Department, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania"},{"name":"Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania"},{"name":"Research Center of the Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"V\u0103c\u0103rescu","sequence":"additional","affiliation":[{"name":"Cardiology Department, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania"},{"name":"Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania"},{"name":"Research Center of the Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marius","family":"Rus","sequence":"additional","affiliation":[{"name":"Department of Medical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-7378-7787","authenticated-orcid":false,"given":"Drago\u0219","family":"Cozma","sequence":"additional","affiliation":[{"name":"Cardiology Department, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania"},{"name":"Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania"},{"name":"Research Center of the Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0320-6779","authenticated-orcid":false,"given":"Dan","family":"Gai\u021b\u0103","sequence":"additional","affiliation":[{"name":"Cardiology Department, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania"},{"name":"Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania"},{"name":"Research Center of the Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constantin-Tudor","family":"Luca","sequence":"additional","affiliation":[{"name":"Cardiology Department, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania"},{"name":"Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania"},{"name":"Research Center of the Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,8,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1016\/S0735-1097(02)01886-7","article-title":"The Incidence of Congenital Heart Disease","volume":"39","author":"Hoffman","year":"2002","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.21037\/tp-21-297","article-title":"Genetics of Congenital Heart Disease: A Narrative Review of Recent Advances and Clinical Implications","volume":"10","author":"Yasuhara","year":"2021","journal-title":"Transl. Pediatr."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Williams, K., Carson, J., and Lo, C. (2019). Genetics of Congenital Heart Disease. Biomolecules, 9.","DOI":"10.3390\/biom9120879"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1007\/s00246-011-0034-5","article-title":"The Contribution of Chromosomal Abnormalities to Congenital Heart Defects: A Population-Based Study","volume":"32","author":"Hartman","year":"2011","journal-title":"Pediatr. Cardiol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"2660","DOI":"10.1093\/eurheartj\/ehab646","article-title":"Atrial Septal Defect in Adulthood: A New Paradigm for Congenital Heart Disease","volume":"43","author":"Brida","year":"2022","journal-title":"Eur. Heart J."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.ccl.2020.04.004","article-title":"Ebstein Anomaly in the Adult Patient","volume":"38","author":"Fuchs","year":"2020","journal-title":"Cardiol. Clin."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.ccl.2020.04.001","article-title":"Atrial Septal Defect","volume":"38","author":"Bradley","year":"2020","journal-title":"Cardiol. Clin."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"S2953","DOI":"10.21037\/jtd.2018.08.92","article-title":"Atrial Septal Defects and Pulmonary Arterial Hypertension","volume":"10","author":"Nashat","year":"2018","journal-title":"J. Thorac. Dis."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1093\/eurheartj\/ehaa554","article-title":"2020 ESC Guidelines for the Management of Adult Congenital Heart Disease: The Task Force for the Management of Adult Congenital Heart Disease of the European Society of Cardiology (ESC). Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Adult Congenital Heart Disease (ISACHD)","volume":"42","author":"Baumgartner","year":"2021","journal-title":"Eur. Heart J."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1017\/S1047951120002656","article-title":"Cyanosis Due to an Isolated Atrial Septal Defect: Case Report and Review of the Literature","volume":"30","author":"Krasemann","year":"2020","journal-title":"Cardiol. Young"},{"key":"ref_11","first-page":"649","article-title":"Superior Sinus Venosus Atrial Septal Defect","volume":"15","author":"Theodoropoulos","year":"2018","journal-title":"J. Geriatr. Cardiol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"103","DOI":"10.4103\/apc.APC_122_17","article-title":"Coronary Sinus Atrial Septal Defect without Persistent Left Superior Vena Cava: Three-Dimensional Imaging of a Rare Defect","volume":"11","author":"Quadros","year":"2018","journal-title":"Ann. Pediatr. Cardiol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"128","DOI":"10.4103\/apc.apc_269_20","article-title":"Transcatheter Closure of Multiple Secundum Atrial Septal Defects Using Multiple Occluder Devices: A Comparative Experience between Pediatric and Adult Patients","volume":"15","author":"Sagar","year":"2022","journal-title":"Ann. Pediatr. Cardiol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"CMC.S15715","DOI":"10.4137\/CMC.S15715","article-title":"Atrial Septal Defects\u2014Clinical Manifestations, Echo Assessment, and Intervention","volume":"8","author":"Martin","year":"2014","journal-title":"Clin. Med. Insights Cardiol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1002\/ccd.22170","article-title":"Characteristics of Adult Patients with Atrial Septal Defects Presenting with Paradoxical Embolism","volume":"74","author":"Bannan","year":"2009","journal-title":"Catheter. Cardiovasc. Interv."},{"key":"ref_16","first-page":"eabc345","article-title":"Percutaneous Closure of Multiple Atrial Septal Defects with Hemodynamic Repercussions: Report of Two Cases in First-Degree Related Adult Patients","volume":"35","author":"Rocha","year":"2022","journal-title":"Arq. Bras. Cardiol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S1047951121001232","article-title":"Secundum Atrial Septal Defects Transcatheter Closure versus Surgery in Adulthood: A 2000-2020 Systematic Review and Meta-Analysis of Intrahospital Outcomes","volume":"31","author":"Rigatelli","year":"2021","journal-title":"Cardiol. Young"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1017\/S1047951112001424","article-title":"Amplatzer Occluder versus CardioSEAL\/STARFlex Occluder: A Meta-Analysis of the Efficacy and Safety of Transcatheter Occlusion for Patent Foramen Ovale and Atrial Septal Defect","volume":"23","author":"Li","year":"2013","journal-title":"Cardiol. Young"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1891\/0730-0832.33.5.268","article-title":"Ebstein Anomaly: A Review","volume":"33","author":"Galea","year":"2014","journal-title":"Neonatal Netw."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1161\/01.CIR.91.1.111","article-title":"Formation of the Tricuspid Valve in the Human Heart","volume":"91","author":"Lamers","year":"1995","journal-title":"Circulation"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"138","DOI":"10.14797\/mdcj-15-2-138","article-title":"Ebstein\u2019s Anomaly","volume":"15","author":"Holst","year":"2019","journal-title":"Methodist. Debakey Cardiovasc. J."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.21037\/jtd.2020.01.18","article-title":"Ebstein\u2019s Anomaly: Contemporary Management Strategies","volume":"12","author":"Sainathan","year":"2020","journal-title":"J. Thorac. Dis."},{"key":"ref_23","first-page":"174","article-title":"Morphologic Spectrum of Ebstein\u2019s Anomaly of the Heart: A Review","volume":"54","author":"Anderson","year":"1979","journal-title":"Mayo Clin. Proc."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1586\/14779072.2015.1087849","article-title":"Ebstein Anomaly Review: What\u2019s Now, What\u2019s Next?","volume":"13","author":"Dearani","year":"2015","journal-title":"Expert. Rev. Cardiovasc. Ther."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1177\/2150135120949235","article-title":"The Congenital Tricuspid Valve Spectrum: From Ebstein to Dysplasia","volume":"11","author":"Stephens","year":"2020","journal-title":"World J. Pediatr. Congenit. Heart Surg."},{"key":"ref_26","first-page":"294","article-title":"Mitral Valve Anomalies Associated with Ebstein\u2019s Malformation of the Tricuspid Valve","volume":"4","author":"Gerlis","year":"1993","journal-title":"Am. J. Cardiovasc. Pathol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1016\/j.jacep.2018.05.024","article-title":"Ebstein\u2019s Anomaly of the Tricuspid Valve: A Natural Laboratory for Re-Entrant Tachycardias","volume":"4","author":"Walsh","year":"2018","journal-title":"JACC Clin. Electrophysiol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.pedneo.2016.08.004","article-title":"Ebstein\u2019s Anomaly: Genetics, Clinical Manifestations, and Management","volume":"58","author":"Yuan","year":"2017","journal-title":"Pediatr. Neonatol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1002\/pd.2935","article-title":"Fetal Ebstein\u2019s Anomaly: Early and Late Appearance","volume":"32","author":"Zimmer","year":"2012","journal-title":"Prenat. Diagn."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"2661","DOI":"10.1093\/eurheartj\/ehm398","article-title":"Ebstein\u2019s Anomaly: Factors Associated with Death in Childhood and Adolescence: A Multi-Centre, Long-Term Study","volume":"28","author":"Kapusta","year":"2007","journal-title":"Eur. Heart J."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"2324709616688710","DOI":"10.1177\/2324709616688710","article-title":"Ebstein Anomaly with QRS Fragmentation on Electrocardiogram","volume":"5","author":"Acharya","year":"2017","journal-title":"J. Investig. Med. High. Impact Case Rep."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"560","DOI":"10.11622\/smedj.2019146","article-title":"Electrocardiography Findings and Clinical Presentation in Ebstein\u2019s Anomaly","volume":"60","author":"Dalakoti","year":"2019","journal-title":"Singap. Med. J."},{"key":"ref_33","first-page":"369","article-title":"Differential Diagnosis and Treatment of Wide QRS Tachycardia in an Ebstein Anomaly Patient","volume":"7","author":"Rosa","year":"2021","journal-title":"Hear. Case Rep."},{"key":"ref_34","first-page":"e10773","article-title":"Ebstein\u2019s Anomaly in Disguise: Follow the Cues and the Diagnosis Can Be Made","volume":"12","author":"Sharma","year":"2020","journal-title":"Cureus"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1055\/s-2000-6900","article-title":"Ebstein\u2019s Anomaly in Adults: Doppler-Echocardiographic Evaluation","volume":"48","author":"Oechslin","year":"2000","journal-title":"Thorac. Cardiovasc. Surg."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"65","DOI":"10.4137\/CMC.S27462","article-title":"Echocardiographic Assessment of the Right Ventricle, from the Conventional Approach to Speckle Tracking and Three-Dimensional Imaging, and Insights into the \u201cRight Way\u201d to Explore the Forgotten Chamber","volume":"9","author":"Kossaify","year":"2015","journal-title":"Clin. Med. Insights Cardiol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"G95","DOI":"10.1530\/ERP-20-0033","article-title":"Echocardiographic Assessment of the Tricuspid and Pulmonary Valves: A Practical Guideline from the British Society of Echocardiography","volume":"7","author":"Zaidi","year":"2020","journal-title":"Echo Res. Pr."},{"key":"ref_38","first-page":"37","article-title":"Role of Magnetic Imaging Resonance Imaging in Ebstein Anomaly","volume":"39","author":"Ibrahim","year":"2022","journal-title":"Benha Med. J."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"ehab724.0243","DOI":"10.1093\/eurheartj\/ehab724.0243","article-title":"Cardiac Magnetic Resonance Imaging in Assessing Heart Function in Patients with Ebstein\u2019s Anomaly","volume":"42","author":"Mochula","year":"2021","journal-title":"Eur. Heart J."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.amjcard.2010.10.058","article-title":"Cardiac Magnetic Resonance Imaging and the Assessment of Ebstein Anomaly in Adults","volume":"107","author":"Yalonetsky","year":"2011","journal-title":"Am. J. Cardiol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1161\/CIRCULATIONAHA.105.592410","article-title":"Arrhythmias in Adult Patients with Congenital Heart Disease","volume":"115","author":"Walsh","year":"2007","journal-title":"Circulation"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1093\/icvts\/ivaa294","article-title":"Surgical Management of Ebstein Anomaly: Impact of the Adult Congenital Heart Disease Anatomical and Physiological Classifications","volume":"32","author":"Homzova","year":"2020","journal-title":"Interact. Cardiovasc. Thorac. Surg."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1053\/j.pcsu.2007.01.007","article-title":"Surgical Management of Ebstein\u2019s Anomaly","volume":"10","author":"Stulak","year":"2007","journal-title":"Semin. Thorac. Cardiovasc. Surg. Pediatr. Card. Surg. Annu."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.xjtc.2020.05.011","article-title":"The Da Silva Cone Operation after the Starnes Procedure for Ebstein\u2019s Anomaly: New Surgical Strategy and Initial Results","volume":"3","author":"Viegas","year":"2020","journal-title":"JTCVS Tech."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1097\/00000658-198210000-00014","article-title":"Surgical Repair of Ebstein\u2019s Anomaly","volume":"196","author":"Danielson","year":"1982","journal-title":"Ann. Surg."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.4103\/0366-6999.230731","article-title":"Outcomes of Ebstein\u2019s Anomaly Patients Treated with Tricuspid Valvuloplasty or Tricuspid Valve Replacement: Experience of a Single Center","volume":"131","author":"Li","year":"2018","journal-title":"Chin. Med. J."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.1016\/j.jacc.2023.04.037","article-title":"Mortality in Patients with Ebstein Anomaly","volume":"81","author":"Dellborg","year":"2023","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"e204","DOI":"10.1097\/MJT.0000000000001067","article-title":"Palliative Care in Heart Failure: A Public Health Emergency","volume":"27","author":"Mosoiu","year":"2020","journal-title":"Am. J. Ther."},{"key":"ref_49","first-page":"376027","article-title":"Heart Transplantation in Congenital Heart Disease: In Whom to Consider and When?","volume":"2013","author":"Schmidt","year":"2013","journal-title":"J. Transpl."},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Karakasis, P., Giannakoulas, G., Theofilis, P., Patoulias, D., and Fragakis, N. (Eur. J. Intern. Med., 2024). Direct Oral Anticoagulants or Vitamin K Antagonists in Adult Patients with Congenital Heart Disease?, Eur. J. Intern. Med., ahead of print.","DOI":"10.1016\/j.ejim.2024.06.017"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"325","DOI":"10.32604\/chd.2024.052267","article-title":"Risk Stratification and Prognosis of Pulmonary Arterial Hypertension Associated with Congenital Heart Disease","volume":"19","author":"Dong","year":"2024","journal-title":"Congenit. Heart Dis."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/16\/4865\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:38:27Z","timestamp":1760110707000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/16\/4865"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,18]]},"references-count":51,"journal-issue":{"issue":"16","published-online":{"date-parts":[[2024,8]]}},"alternative-id":["jcm13164865"],"URL":"https:\/\/doi.org\/10.3390\/jcm13164865","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,18]]}}}