{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T17:11:08Z","timestamp":1788801068744,"version":"build-2803163510"},"reference-count":68,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2024,9,2]],"date-time":"2024-09-02T00:00:00Z","timestamp":1725235200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Deanship of Graduate Studies and Scientific Research, Jazan University, Saudi Arabia","award":["RG24-S0111"],"award-info":[{"award-number":["RG24-S0111"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Magnetic resonance imaging (MRI) has emerged as a promising and appealing alternative to endoscopy in the objective assessment of patients with inflammatory bowel disease (IBD). Diffusion-weighted imaging (DWI) is a specialized imaging technique that enables the mapping of water molecule diffusion within biological tissues, eliminating the need for intravenous gadolinium contrast injection. It is expanding the capability of traditional MRI sequences in Ulcerative Colitis (UC). Recently, there has been growing interest in the application of intravoxel incoherent motion (IVIM) imaging in the field of IBD. This technique combines diffusion and perfusion information, making it a valuable tool for assessing IBD treatment response. Previous studies have extensively studied the use of DWI techniques for evaluating the severity of activity in IBD. However, the majority of these studies have primarily focused on Crohn\u2019s disease (CD), with only a limited number of reports specifically examining UC. Therefore, this review briefly introduces the basics of DWI and IVIM imaging and conducts a review of relevant studies that have investigated its application in UC to show whether these techniques are useful techniques for evaluating patients with UC in terms of detection, characterization, and quantification of disease activity. Through the extensive literature survey, most of these studies indicate that DWI proves valuable in the differential diagnosis of UC and could be used as an effective modality for staging UC.<\/jats:p>","DOI":"10.3390\/jcm13175204","type":"journal-article","created":{"date-parts":[[2024,9,2]],"date-time":"2024-09-02T10:07:35Z","timestamp":1725271655000},"page":"5204","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Imaging of Ulcerative Colitis: The Role of Diffusion-Weighted Magnetic Resonance Imaging"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5774-5466","authenticated-orcid":false,"given":"Ali S.","family":"Alyami","sequence":"first","affiliation":[{"name":"Department of Diagnostic Radiography Technology, College of Nursing and Health Sciences, Jazan University, Jazan 45142, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,9,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"100851","DOI":"10.1016\/j.disamonth.2019.02.004","article-title":"A comprehensive review and update on ulcerative colitis","volume":"65","author":"Gajendran","year":"2019","journal-title":"Disease-A-Month"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2198","DOI":"10.1097\/MIB.0000000000000080","article-title":"Fibrosis in ulcerative colitis: Mechanisms, features, and consequences of a neglected problem","volume":"20","author":"Gordon","year":"2014","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1111\/apt.14526","article-title":"Fibrosis in ulcerative colitis is directly linked to severity and chronicity of mucosal inflammation","volume":"47","author":"Gordon","year":"2018","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1111\/apt.14575","article-title":"ulcerative colitis submucosal fibrosis and inflammation: More than just strictures","volume":"47","author":"Magro","year":"2018","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1093\/ecco-jcc\/jjw076","article-title":"Fibrotic and vascular remodelling of colonic wall in patients with active ulcerative colitis","volume":"10","author":"Ippolito","year":"2016","journal-title":"J. Crohn\u2019s Colitis"},{"key":"ref_6","first-page":"564","article-title":"Ulcerative colitis\u2014Diagnostic and therapeutic algorithms","volume":"117","author":"Kucharzik","year":"2020","journal-title":"Dtsch. \u00c4rzteblatt Int."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1080\/03007995.2022.2081453","article-title":"Endoscopic mucosal healing and histologic remission in ulcerative colitis: A systematic literature review of clinical, quality-of-life and economic outcomes","volume":"38","author":"Pandey","year":"2022","journal-title":"Curr. Med. Res. Opin."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1056\/NEJMra1403718","article-title":"Cancers complicating inflammatory bowel disease","volume":"372","author":"Beaugerie","year":"2015","journal-title":"N. Engl. J. Med."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.gie.2006.02.005","article-title":"ASGE guideline: Endoscopy in the diagnosis and treatment of inflammatory bowel disease","volume":"63","author":"Leighton","year":"2006","journal-title":"Gastrointest. Endosc."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1002\/ibd.20997","article-title":"Importance of mucosal healing in ulcerative colitis","volume":"16","author":"Lichtenstein","year":"2010","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1016\/j.cgh.2016.01.015","article-title":"Mucosal healing is associated with improved long-term outcomes of patients with ulcerative colitis: A systematic review and meta-analysis","volume":"14","author":"Shah","year":"2016","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1053\/j.gastro.2020.12.031","article-title":"STRIDE-II: An update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining therapeutic goals for treat-to-target strategies in IBD","volume":"160","author":"Turner","year":"2021","journal-title":"Gastroenterology"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1097\/01.MIB.0000442681.85545.31","article-title":"Clinical utility of fecal biomarkers for the diagnosis and management of inflammatory bowel disease","volume":"20","author":"Kopylov","year":"2014","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/j.giec.2022.05.001","article-title":"Imaging evaluation of inflammatory bowel disease complications","volume":"32","author":"Bartlett","year":"2022","journal-title":"Gastrointest. Endosc. Clin."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Biondi, M., Bicci, E., Danti, G., Flammia, F., Chiti, G., Palumbo, P., Bruno, F., Borgheresi, A., Grassi, R., and Grassi, F. (2022). The role of magnetic resonance enterography in Crohn\u2019s disease: A review of recent literature. Diagnostics, 12.","DOI":"10.3390\/diagnostics12051236"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1016\/j.acra.2021.07.025","article-title":"CT and MRI Evaluations in Crohn\u2019s Complications: A Guide for the Radiologist","volume":"29","author":"Minordi","year":"2022","journal-title":"Acad. Radiol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1136\/gut.2003.037390","article-title":"Comparison of magnetic resonance imaging colonography with conventional colonoscopy for the assessment of intestinal inflammation in patients with inflammatory bowel disease: A feasibility study","volume":"54","author":"Schreyer","year":"2005","journal-title":"Gut"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1002\/ibd.20140","article-title":"MR colonography without bowel purgation for the assessment of inflammatory bowel diseases: Diagnostic accuracy and patient acceptance","volume":"13","author":"Langhorst","year":"2007","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1007\/s00247-018-4169-x","article-title":"Can diffusion weighting replace gadolinium enhancement in magnetic resonance enterography for inflammatory bowel disease in children?","volume":"48","author":"Khachab","year":"2018","journal-title":"Pediatr. Radiol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"20150840","DOI":"10.1259\/bjr.20150840","article-title":"Prospective evaluation of free-breathing diffusion-weighted imaging for the detection of inflammatory bowel disease with MR enterography in childhood population","volume":"89","author":"Dubron","year":"2016","journal-title":"Br. J. Radiol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1148\/radiol.2451061244","article-title":"MR colonography with limited bowel preparation: Patient acceptance compared with that of full-preparation colonoscopy","volume":"245","author":"Florie","year":"2007","journal-title":"Radiology"},{"key":"ref_22","first-page":"468","article-title":"Evaluation of ulcerative colitis using diffusion-weighted imaging","volume":"57","author":"Aoyagi","year":"2010","journal-title":"Hepato-gastroenterology"},{"key":"ref_23","first-page":"293","article-title":"Is quantitative diffusion-weighted MRI a reliable method in the assessment of the inflammatory activity in ulcerative colitis","volume":"16","author":"Soylu","year":"2010","journal-title":"Diagn. Interv. Radiol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1136\/gut.2009.197665","article-title":"Diffusion-weighted magnetic resonance without bowel preparation for detecting colonic inflammation in inflammatory bowel disease","volume":"59","author":"Oussalah","year":"2010","journal-title":"Gut"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1177\/0284185120931689","article-title":"Intravoxel incoherent motion MRI in evaluating inflammatory activity in ulcerative colitis: A pilot study","volume":"62","author":"Pasicz","year":"2021","journal-title":"Acta Radiol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1113\/jphysiol.1981.sp013981","article-title":"Ion diffusion modified by tortuosity and volume fraction in the extracellular microenvironment of the rat cerebellum","volume":"321","author":"Nicholson","year":"1981","journal-title":"J. Physiol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/nbm.1940080704","article-title":"Diffusion-weighted imaging in tissues: Theoretical models","volume":"8","author":"Szafer","year":"1995","journal-title":"NMR Biomed."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1002\/jmri.25325","article-title":"Diffusion-weighted MRI in Crohn\u2019s disease: Current status and recommendations","volume":"44","author":"Dohan","year":"2016","journal-title":"J. Magn. Reson. Imaging"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.2214\/AJR.06.1403","article-title":"Diffusion-weighted MRI in the body: Applications and challenges in oncology","volume":"188","author":"Koh","year":"2007","journal-title":"Am. J. Roentgenol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1593\/neo.81328","article-title":"Diffusion-weighted magnetic resonance imaging as a cancer biomarker: Consensus and recommendations","volume":"11","author":"Padhani","year":"2009","journal-title":"Neoplasia"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1148\/radiology.161.2.3763909","article-title":"MR imaging of intravoxel incoherent motions: Application to diffusion and perfusion in neurologic disorders","volume":"161","author":"Breton","year":"1986","journal-title":"Radiology"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1148\/radiol.2015150244","article-title":"Clinical intravoxel incoherent motion and diffusion MR imaging: Past, present, and future","volume":"278","author":"Iima","year":"2016","journal-title":"Radiology"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.crohns.2013.02.020","article-title":"Imaging techniques for assessment of inflammatory bowel disease: Joint ECCO and ESGAR evidence-based consensus guidelines","volume":"7","author":"Panes","year":"2013","journal-title":"J. Crohn\u2019s Colitis"},{"key":"ref_34","first-page":"1566","article-title":"Diagnostic accuracy of magnetic resonance colonography for the evaluation of disease activity and severity in ulcerative colitis: A prospective study","volume":"62","author":"Rimola","year":"2012","journal-title":"Gut"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/S2468-1253(18)30054-2","article-title":"Diffusion-weighted MRI in inflammatory bowel disease","volume":"3","author":"Pouillon","year":"2018","journal-title":"Lancet Gastroenterol. Hepatol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.clinimag.2017.03.019","article-title":"Comparison of T2-weighted imaging, diffusion-weighted imaging and contrast-enhanced T1-weighted MR imaging for evaluating perianal fistulas","volume":"44","author":"Baik","year":"2017","journal-title":"Clin. Imaging"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"2906","DOI":"10.1007\/s00330-014-3302-y","article-title":"Diffusion-weighted MR imaging for the diagnosis of abscess complicating fistula-in-ano: Preliminary experience","volume":"24","author":"Dohan","year":"2014","journal-title":"Eur. Radiol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1148\/radiol.2015150809","article-title":"MR enterography for the evaluation of small-bowel inflammation in Crohn disease by using diffusion-weighted imaging without intravenous contrast material: A prospective noninferiority study","volume":"278","author":"Seo","year":"2016","journal-title":"Radiology"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1002\/jmri.22504","article-title":"MRI in patients with inflammatory bowel disease","volume":"33","author":"Gee","year":"2011","journal-title":"J. Magn. Reson. Imaging"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1148\/radiol.2018171737","article-title":"Consensus recommendations for evaluation, interpretation, and utilization of computed tomography and magnetic resonance enterography in patients with small bowel Crohn\u2019s disease","volume":"286","author":"Bruining","year":"2018","journal-title":"Radiology"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"S192","DOI":"10.1016\/j.acra.2021.02.022","article-title":"Diagnostic accuracy of magnetic resonance enterography in the evaluation of colonic abnormalities in Crohn\u2019s disease: A systematic review and meta-analysis","volume":"28","author":"Chavoshi","year":"2021","journal-title":"Acad. Radiol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/S2468-1253(19)30194-3","article-title":"Improving the quality of surveillance colonoscopy in inflammatory bowel disease","volume":"4","author":"Iacucci","year":"2019","journal-title":"Lancet Gastroenterol. Hepatol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1148\/rg.2017160064","article-title":"MR enterography of inflammatory bowel disease with endoscopic correlation","volume":"37","author":"Kaushal","year":"2017","journal-title":"Radiographics"},{"key":"ref_44","first-page":"1323","article-title":"Ulcerative colitis: Diagnosis and treatment","volume":"76","author":"Langan","year":"2007","journal-title":"Am. Fam. Physician"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1148\/rg.2017160121","article-title":"Beyond the bowel: Extraintestinal manifestations of inflammatory bowel disease","volume":"37","author":"Olpin","year":"2017","journal-title":"Radiographics"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1093\/gastro\/gou028","article-title":"Colonoscopic evaluation in ulcerative colitis","volume":"2","author":"Paine","year":"2014","journal-title":"Gastroenterol. Rep."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"e230131","DOI":"10.1148\/rg.230131","article-title":"MR Enterography in Ulcerative Colitis: Beyond Endoscopy","volume":"44","author":"Radmard","year":"2023","journal-title":"Radiographics"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1007\/s00247-017-3833-x","article-title":"Colonic inflammation in pediatric inflammatory bowel disease: Detection with magnetic resonance enterography","volume":"47","author":"Campari","year":"2017","journal-title":"Pediatr. Radiol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1007\/s00261-004-0284-2","article-title":"Ulcerative colitis: Value of MR imaging","volume":"30","author":"Maccioni","year":"2005","journal-title":"Abdom. Imaging"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1148\/rg.263055149","article-title":"Best cases from the AFIP-Ulcerative colitis","volume":"26","author":"Roggeveen","year":"2006","journal-title":"Radiographics"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1259\/bjr\/36231529","article-title":"Patient experiences of MR colonography and colonoscopy: A qualitative study","volume":"85","author":"Hafeez","year":"2012","journal-title":"Br. J. Radiol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1093\/ibd\/izac040","article-title":"A Practical Index to Distinguish Backwash Ileitis From Crohn\u2019s Terminal Ileitis in MR Enterography","volume":"29","author":"Khosravi","year":"2023","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1038\/ncpgasthep1028","article-title":"Technology Insight: New techniques for imaging the gut in patients with IBD","volume":"5","author":"Bruining","year":"2008","journal-title":"Nat. Clin. Pract. Gastroenterol. Hepatol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1148\/radiol.2513081184","article-title":"Crohn disease of the small bowel: Comparison of CT enterography, MR enterography, and small-bowel follow-through as diagnostic techniques","volume":"251","author":"Lee","year":"2009","journal-title":"Radiology"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1148\/radiol.12111658","article-title":"MR imaging of the small bowel","volume":"264","author":"Masselli","year":"2012","journal-title":"Radiology"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"917","DOI":"10.3748\/wjg.v22.i3.917","article-title":"Inflammatory bowel disease imaging: Current practice and future directions","volume":"22","author":"Kilcoyne","year":"2016","journal-title":"World J. Gastroenterol."},{"key":"ref_57","doi-asserted-by":"crossref","unstructured":"Al-Jabri, R., Wetwittayakhlang, P., and Lakatos, P.L. (2023). Monitoring of Inflammatory Bowel Disease in Pregnancy: A Review of the Different Modalities. J. Clin. Med., 12.","DOI":"10.3390\/jcm12237343"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1038\/ajg.2013.385","article-title":"Diffusion-weighted magnetic resonance imaging in ileocolonic Crohn\u2019s disease: Validation of quantitative index of activity","volume":"109","author":"Hordonneau","year":"2014","journal-title":"Off. J. Am. Coll. Gastroenterol. ACG"},{"key":"ref_59","first-page":"716","article-title":"Accuracy of diffusion-weighted magnetic resonance colonography in assessing mucosal healing and the treatment response in patients with ulcerative colitis","volume":"11","author":"Laurent","year":"2017","journal-title":"J. Crohn\u2019s Colitis"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1186\/s43055-023-01148-0","article-title":"The role of magnetic resonance enterography and diffusion-weighted imaging in pediatric inflammatory bowel disease compared to endoscopic and clinical activity scores: Pilot study","volume":"54","author":"Saleh","year":"2023","journal-title":"Egypt. J. Radiol. Nucl. Med."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"9785","DOI":"10.3748\/wjg.v21.i33.9785","article-title":"Diffusion-weighted magnetic resonance imaging without bowel preparation for detection of ulcerative colitis","volume":"21","author":"Yu","year":"2015","journal-title":"World J. Gastroenterol. WJG"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/j.cgh.2019.11.052","article-title":"Use of cross-sectional imaging for tight monitoring of inflammatory bowel diseases","volume":"18","author":"Allocca","year":"2020","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1038\/ajg.2015.233","article-title":"Selecting therapeutic targets in inflammatory bowel disease (STRIDE): Determining therapeutic goals for treat-to-target","volume":"110","author":"Sandborn","year":"2015","journal-title":"Off. J. Am. Coll. Gastroenterol. ACG"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1053\/j.gastro.2013.10.055","article-title":"Accuracy of magnetic resonance enterography in assessing response to therapy and mucosal healing in patients with Crohn\u2019s disease","volume":"146","author":"Rimola","year":"2014","journal-title":"Gastroenterology"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"519","DOI":"10.3109\/00365521.2014.1003398","article-title":"Plain magnetic resonance imaging as an alternative in evaluating inflammation and bowel damage in inflammatory bowel disease\u2013a prospective comparison with conventional magnetic resonance follow-through","volume":"50","author":"Munkholm","year":"2015","journal-title":"Scand. J. Gastroenterol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"40","DOI":"10.2214\/AJR.15.15862","article-title":"DWI at MR enterography for evaluating bowel inflammation in Crohn disease","volume":"207","author":"Park","year":"2016","journal-title":"Am. J. Roentgenol."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"100217","DOI":"10.1016\/j.ejro.2020.01.006","article-title":"Evaluation of ileal Crohn\u2019s disease response to TNF antagonists: Validation of MR enterography for assessing response. Initial results","volume":"7","author":"Gordic","year":"2020","journal-title":"Eur. J. Radiol. Open"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"e2329639","DOI":"10.2214\/AJR.23.29639","article-title":"ADC values for detecting bowel inflammation and biologic therapy response in patients with Crohn disease: A post hoc prospective trial analysis","volume":"222","author":"Rimola","year":"2024","journal-title":"Am. J. Roentgenol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/17\/5204\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:47:19Z","timestamp":1760111239000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/17\/5204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,2]]},"references-count":68,"journal-issue":{"issue":"17","published-online":{"date-parts":[[2024,9]]}},"alternative-id":["jcm13175204"],"URL":"https:\/\/doi.org\/10.3390\/jcm13175204","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,2]]}}}