{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:25:06Z","timestamp":1760145906767,"version":"build-2065373602"},"reference-count":20,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T00:00:00Z","timestamp":1725580800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Promotion and Mutual Aid Corporation for Private Schools of Japan"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Sudden volcanic eruptions can lead to volcanic ash entering the eyes, causing severe discomfort and complicating evacuation efforts. The specific effects of volcanic ash on ocular tissues, especially when wearing soft contact lenses (SCLs), are not well documented, prompting this experimental investigation. Methods: White rabbits with normal eyes were randomly divided into three groups: (1) a bare eye group: bare eye + volcanic ash exposure + eye washing, (2) an SCL group: SCL-wearing eye + volcanic ash exposure + eye washing, and (3) a control group: eye washing only. In groups 1 and 2, volcanic ash was applied to one eye under topical anesthesia, followed by immediate saline rinsing. Slit-lamp microscopy and histopathological analysis were conducted after euthanasia. Results: Slit-lamp and histopathological examinations revealed more significant corneal and conjunctival erosion in the bare eye group compared to the SCL group, which showed limited damage. The control group displayed no ocular damage. Conclusions: Guidelines from the \u201cVolcanic Ash Health Effects: A Guide for the Public\u201d by the National Research Institute for Earth Science and Disaster Resilience recommend removing SCLs during ashfall. Our findings suggest that the damage to the corneal and conjunctival epithelium is less severe in SCL-wearing eyes than in bare eyes, recommending that SCL wearers prioritize evacuation over lens removal during sudden ashfall.<\/jats:p>","DOI":"10.3390\/jcm13175281","type":"journal-article","created":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T03:22:46Z","timestamp":1725592966000},"page":"5281","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Experimental Study on Ocular Surface Protection by Soft Contact Lenses Due to Volcanic Ash Exposure"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4260-6687","authenticated-orcid":false,"given":"Hiroshi","family":"Toshida","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Juntendo University Shizuoka Hospital, 1129 Nagaoka, Izunokuni 410-2295, Japan"},{"name":"Shizuoka Research Center for Disaster Medicine, Juntendo University, Izunokuni 410-2295, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Matsuzaki","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Juntendo University Shizuoka Hospital, 1129 Nagaoka, Izunokuni 410-2295, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Miyazaki","sequence":"additional","affiliation":[{"name":"Shizuoka Research Center for Disaster Medicine, Juntendo University, Izunokuni 410-2295, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,9,6]]},"reference":[{"key":"ref_1","unstructured":"(2024, August 13). The Smithsonian Institution\u2019s Global Volcanism Program. Available online: https:\/\/volcano.si.edu\/."},{"key":"ref_2","unstructured":"(2024, August 13). The International Volcanic Health Hazard Network. Available online: https:\/\/www.ivhhn.org\/."},{"key":"ref_3","unstructured":"The International Volcanic Health Hazard Network (2024, August 13). Health Impacts of Volcanic Ash. Available online: https:\/\/www.ivhhn.org\/index.php\/information\/health-impacts-volcanic-ash."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1080\/08164622.2022.2033604","article-title":"Global contact lens prescribing 2000\u20132020","volume":"105","author":"Morgan","year":"2022","journal-title":"Clin. Exp. Optom."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.clae.2021.02.002","article-title":"CLEAR\u2014Medical use of contact lenses","volume":"44","author":"Jacobs","year":"2021","journal-title":"Contact Lens Anterior Eye"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.optm.2007.02.021","article-title":"The safety and efficacy of contact lens wear in the industrial and chemical workplace","volume":"78","author":"Tyhurst","year":"2007","journal-title":"Optometry"},{"key":"ref_7","first-page":"237","article-title":"Guidelines for contact lens use in industry","volume":"29","author":"Randolph","year":"1987","journal-title":"J. Occup. Med."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1080\/02713680701827696","article-title":"Effect of retinol palmitate eye drops on experimental keratoconjunctival epithelial damage induced by n-heptanol in rabbit","volume":"33","author":"Toshida","year":"2008","journal-title":"Curr. Eye Res."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1001\/archopht.1969.00990020012003","article-title":"Diagnostic tests in the sicca syndrome","volume":"82","year":"1969","journal-title":"Arch. Ophthalmol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"925","DOI":"10.2307\/4592281","article-title":"Observations on air pollution aspects of Irazu volcano, Costa Rica Public Health Reports","volume":"79","author":"Horton","year":"1964","journal-title":"Public Health Rep."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1001\/archopht.1983.01040010376003","article-title":"Ocular effects following the volcanic eruptions of Mount St. Helens","volume":"101","author":"Fraunfelder","year":"1983","journal-title":"Arch. Ophthalmol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.ophtha.2004.09.031","article-title":"Effects of volcanic ash on ocular symptoms: Results of a 10-year survey on schoolchildren","volume":"112","author":"Kimura","year":"2005","journal-title":"Ophthalmology"},{"key":"ref_13","first-page":"262","article-title":"Ocular findings in volcanic fog induced conjunctivitis","volume":"70","author":"Camara","year":"2011","journal-title":"Hawaii Med. J."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s12940-024-01056-4","article-title":"Health impact of the Tajogaite volcano eruption in La Palma population (ISVOLCAN study): Rationale, design, and preliminary results from the first 1002 participants","volume":"23","author":"Ferrer","year":"2024","journal-title":"Environ. Health"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1136\/bmj.296.6637.1616","article-title":"100 years of contact lenses","volume":"296","author":"Halliday","year":"1987","journal-title":"Br. Med. J."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.clae.2016.11.005","article-title":"Mechanical properties of contact lenses: The contribution of measurement techniques and clinical feedback to 50 years of materials development","volume":"40","author":"Bhamra","year":"2017","journal-title":"Contact Lens Anterior Eye"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1111\/j.1755-3768.1982.tb00606.x","article-title":"The use of contact lenses in environments with organic solvents, acids or alkalies","volume":"60","author":"Nilsson","year":"1982","journal-title":"Acta Ophthalmol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1093\/milmed\/166.1.71","article-title":"Initial 67th Combat Support Hospital Optometry Services in Taszar, Hungary, during Operation Joint Endeavor","volume":"166","author":"Bancroft","year":"2001","journal-title":"Mil. Med."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"e002476","DOI":"10.1136\/military-2023-002476","article-title":"Contact lens-related complications in austere conditions among military personnel: A systematic review","volume":"12","author":"Bhanot","year":"2023","journal-title":"BMJ Mil. Health"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1080\/00039896.1990.10118757","article-title":"Health effects of volcanic ash: A repeat study","volume":"45","author":"Yano","year":"1990","journal-title":"Arch. Environ. 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