{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T04:36:43Z","timestamp":1791434203103,"version":"4.3.3"},"reference-count":68,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T00:00:00Z","timestamp":1727222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Objective: The aim of this study was to investigate the use of image-guided volumetry in cerebellar infarction during the decision-making process for surgery. Particular emphasis was placed on the ratio of the infarction volume to the cerebellar volume or cranial posterior fossa volume. Methods: A retrospective, multicenter, multidisciplinary study design was selected. Statistical methods such as regression analysis and ROC analysis included the volumetric data of the infarction, the posterior fossa and the cerebellum itself as new factors. Results: Thirty-eight patients (mean age 75 (SD: 13.93) years, 16 (42%) female patients) were included. The mean infarction volume was 37.79 (SD: 25.24) cm3. Patients treated surgically had a 2.05-fold larger infarction than those managed without surgery (p \u2264 0.001). Medical and surgical treatment revealed a significant difference in the ratio of the cranial posterior fossa volume to the infarction volume (medical 12.05, SD:9.09; surgical 5.14, SD: 5,65; p \u2264 0.001) and the ratio of the cerebellar volume to the infarction volume (medical 8.55, SD: 5.97; surgical 3.82, SD: 3.39; p \u2264 0.001). Subsequent multivariate regression analysis for surgical therapy showed significant results only for the posterior fossa volume to infarction volume ratio \u2264\/&gt; 4:1 (OR: 1.162, CI: 1.007\u20131.341, p = 0.04). Younger (\u226460 years) patients also had a significantly better outcome at discharge (p \u2264 0.017). A cut-off value for the infarction volume of 31.35 cm3 (sensitivity = 0.875, specificity = 0.2) was determined for the necessity of surgery. Conclusions: Volumetric data on the infarction, the posterior fossa and the cerebellum itself could be meaningful in decision-making towards surgery.<\/jats:p>","DOI":"10.3390\/jcm13195689","type":"journal-article","created":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T04:01:24Z","timestamp":1727236884000},"page":"5689","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Volumetry as a Criterion for Suboccipital Craniectomy after Cerebellar Infarction"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1237-5347","authenticated-orcid":false,"given":"Thomas","family":"Kapapa","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University Hospital Ulm, Albert-Einstein-Allee 23, 89081 Ulm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6653-701X","authenticated-orcid":false,"given":"Andrej","family":"Pala","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University Hospital Ulm, Albert-Einstein-Allee 23, 89081 Ulm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burkhard","family":"Alber","sequence":"additional","affiliation":[{"name":"Department of Neurology, Bezirkskrankenhaus G\u00fcnzburg, Lindenallee 2, 89321 Ulm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uwe Max","family":"Mauer","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Military Hospital Ulm, Oberer Eselsberg 40, 89081 Ulm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Harth","sequence":"additional","affiliation":[{"name":"Department of Neurology, Military Hospital Ulm, Oberer Eselsberg 40, 89081 Ulm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3759-356X","authenticated-orcid":false,"given":"Hermann","family":"Neugebauer","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Hospital Ulm, Oberer Eselsberg 45, 89081 Ulm, Germany"},{"name":"Department of Neurology, University of Wurzburg, Josef-Schneider-Strasse 11, 97080 Wurzburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Sailer","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, University Hospital Ulm, Eythstrasse 24, 89075 Ulm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6823-5493","authenticated-orcid":false,"given":"Kornelia","family":"Kreiser","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Rehabilitation Hospital Ulm, University Hospital Ulm, Oberer Eselsberg 45, 89081 Ulm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernd","family":"Schmitz","sequence":"additional","affiliation":[{"name":"Section Neuroradiology, University Hospital Ulm, Albert-Einstein-Allee 23, 89081 Ulm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9004-4335","authenticated-orcid":false,"given":"Katharina","family":"Althaus","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Hospital Ulm, Oberer Eselsberg 45, 89081 Ulm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,9,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Hayward, M.D., and Majmundar, M.K. 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