{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T18:48:13Z","timestamp":1790880493576,"version":"4.1.0"},"reference-count":33,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T00:00:00Z","timestamp":1727654400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: The aim of this study was to report the visual and refractive outcomes of nanophthalmic eyes undergoing phacoemulsification at a tertiary cataract center. Methods: This is a prospective consecutive case series. Patients with an axial length of \u226420.5 mm who underwent phacoemulsification at a tertiary cataract center in Hong Kong were included. Eyes undergoing extracapsular cataract extraction or with a previous history of intraocular surgery including trabeculectomy were excluded. The outcome measures were the corrected distance visual acuity (CDVA) and refractive status at four months post-operation. Different intraocular lens formulas were used to compare the refractive outcomes. Results: Out of 22,847 cataract surgeries performed from May 2011 to March 2020, 14 eyes (0.06%) of 10 patients had axial lengths of \u226420.5 mm and underwent phacoemulsification. The mean axial length was 20.13 \u00b1 0.44 mm. Out of these fourteen eyes, three (21%) had postoperative myopic shift with spherical equivalent refraction of more than or equal to 1D compared to the original target. Eleven eyes (79%) had postoperative refraction within 0.5D compared to the original target. Nine out of fourteen eyes (64%) had improvements in postoperative vision. There were no intraoperative complications. When comparing the Hoffer Q, Holladay 1, Holladay 2, Haigis and Hill-RBF 2.0 formulas, there was no significant difference in the absolute errors between the five formulas (p = 0.072). Conclusions: There was no significant difference in the mean absolute errors between the Hoffer Q, Holladay 1, Holladay 2, Haigis and Hill-RBF 2.0 formulas. Myopic shift was not uncommon, and more studies on intraocular lens (IOL) power calculation for short eyes are warranted.<\/jats:p>","DOI":"10.3390\/jcm13195852","type":"journal-article","created":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T08:09:52Z","timestamp":1727683792000},"page":"5852","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Visual and Refractive Outcomes after Phacoemulsification Cataract Surgery in Nanophthalmic Eyes"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0420-9456","authenticated-orcid":false,"given":"Tracy H. T.","family":"Lai","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Tseung Kwan O Hospital, 2 Po Ning Lane, Tseung Kwan O, Hong Kong"},{"name":"Department of Ophthalmology, United Christian Hospital, 130 Hip Wo Street, Kwun Tong, Hong Kong"},{"name":"Department of Ophthalmology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong"},{"name":"Wu Ho Loo Ning Cataract Center, Tseung Kwan O Hospital, 2 Po Ning Lane, Tseung Kwan O, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey Y. T.","family":"Tse","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Tseung Kwan O Hospital, 2 Po Ning Lane, Tseung Kwan O, Hong Kong"},{"name":"Department of Ophthalmology, United Christian Hospital, 130 Hip Wo Street, Kwun Tong, Hong Kong"},{"name":"Department of Ophthalmology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong"},{"name":"Wu Ho Loo Ning Cataract Center, Tseung Kwan O Hospital, 2 Po Ning Lane, Tseung Kwan O, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline W. T.","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Tseung Kwan O Hospital, 2 Po Ning Lane, Tseung Kwan O, Hong Kong"},{"name":"Department of Ophthalmology, United Christian Hospital, 130 Hip Wo Street, Kwun Tong, Hong Kong"},{"name":"Department of Ophthalmology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong"},{"name":"Wu Ho Loo Ning Cataract Center, Tseung Kwan O Hospital, 2 Po Ning Lane, Tseung Kwan O, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9440-8063","authenticated-orcid":false,"given":"Kenneth K. W.","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Tseung Kwan O Hospital, 2 Po Ning Lane, Tseung Kwan O, Hong Kong"},{"name":"Department of Ophthalmology, United Christian Hospital, 130 Hip Wo Street, Kwun Tong, Hong Kong"},{"name":"Department of Ophthalmology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong"},{"name":"Wu Ho Loo Ning Cataract Center, Tseung Kwan O Hospital, 2 Po Ning Lane, Tseung Kwan O, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,9,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"534","DOI":"10.3129\/i09-142","article-title":"Phacoemulsification in patients with nanophthalmos","volume":"44","author":"Yuzbasioglu","year":"2009","journal-title":"Can. J. Ophthalmol. J. Can. D\u2019Ophtalmol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1038\/sj.eye.6702742","article-title":"Management of glaucoma in patients with nanophthalmos","volume":"22","author":"Yalvac","year":"2008","journal-title":"Eye"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1016\/S0161-6420(82)34687-4","article-title":"Nanophthalmos: A perspective on identification and therapy","volume":"89","author":"Singh","year":"1982","journal-title":"Ophthalmology"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1111\/j.1442-9071.2007.01484.x","article-title":"Nanophthalmos in a Melanesian population","volume":"35","author":"Tay","year":"2007","journal-title":"Clin. Exp. Ophthalmol."},{"key":"ref_5","first-page":"371","article-title":"Nanophthalmos with uveal effusion: A new clinical entity","volume":"72","author":"Brockhurst","year":"1974","journal-title":"Trans. Am. Ophthalmol. Soc."},{"key":"ref_6","first-page":"117","article-title":"Implantation of an intraocular lens in a case of nanophthalmos","volume":"13","author":"Susanna","year":"1987","journal-title":"Eye Contact Lens"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1016\/S0161-6420(03)00563-3","article-title":"Angle closure in younger patients","volume":"110","author":"Ritch","year":"2003","journal-title":"Ophthalmology"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.survophthal.2005.12.005","article-title":"Cataract surgery in the small adult eye","volume":"51","author":"Wladis","year":"2006","journal-title":"Surv. Ophthalmol."},{"key":"ref_9","first-page":"84","article-title":"Cataract surgery in adult eyes with short axial length","volume":"34","author":"Elhusseiny","year":"2023","journal-title":"Curr. Opin. Ophthalmol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.ophtha.2012.07.082","article-title":"Cataract surgery in patients with nanophthalmos","volume":"120","author":"Steijns","year":"2013","journal-title":"Ophthalmology"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.jcrs.2012.08.057","article-title":"Outcomes of phacoemulsification and intraocular lens implantation in microphthalmos and nanophthalmos","volume":"39","author":"Day","year":"2013","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/j.ajo.2011.12.006","article-title":"Cataract surgery in eyes with nanophthalmos and relative anterior microphthalmos","volume":"153","author":"Jung","year":"2012","journal-title":"Am. J. Ophthalmol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1016\/j.jcrs.2006.02.051","article-title":"Nanophthalmos: Ultrasound biomicroscopy and Pentacam assessment of angle structures before and after cataract surgery","volume":"32","author":"Sharan","year":"2006","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.jcrs.2003.07.009","article-title":"Cataract surgery in patients with nanophthalmos: Results and complications","volume":"30","author":"Wu","year":"2004","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/S0886-3350(01)01161-0","article-title":"Phacoemulsification and intraocular lens implantation in nanophthalmic eyes: Report of a medium-size series","volume":"28","author":"Faucher","year":"2002","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1097\/IAE.0b013e318218a95a","article-title":"Transscleral albumin diffusion and suprachoroidal albumin concentration in uveal effusion syndrome","volume":"32","author":"Jackson","year":"2012","journal-title":"Retina"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/S0886-3350(00)00787-2","article-title":"Piggyback foldable intraocular lens implantation in patients with microphthalmos","volume":"27","author":"Oshika","year":"2001","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1016\/S0886-3350(97)80317-3","article-title":"Intraocular lens power calculation for microphthalmos","volume":"23","author":"Inatomi","year":"1997","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"29","DOI":"10.4103\/IJO.IJO_1219_23","article-title":"Optimization of biometry for best refractive outcome in cataract surgery","volume":"72","author":"Gupta","year":"2024","journal-title":"Indian J. Ophthalmol."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Stopyra, W., Cooke, D.L., and Grzybowski, A. (2024). A Review of Intraocular Lens Power Calculation Formulas Based on Artificial Intelligence. J. Clin. Med., 13.","DOI":"10.3390\/jcm13020498"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/ICU.0000000000001014","article-title":"Online intraocular lens calculation","volume":"35","author":"Buonsanti","year":"2024","journal-title":"Curr. Opin. Ophthalmol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1007\/s10792-021-02191-4","article-title":"Comparing the accuracy of new intraocular lens power calculation formulae in short eyes after cataract surgery: A systematic review and meta-analysis","volume":"42","author":"Luo","year":"2022","journal-title":"Int. Ophthalmol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"2881","DOI":"10.1007\/s40123-023-00799-6","article-title":"Intraocular Lens Power Calculation Formulas\u2014A Systematic Review","volume":"12","author":"Stopyra","year":"2023","journal-title":"Ophthalmol. Ther."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Aramberri, J., Hoffer, K.J., Olsen, T., Savini, G., and Shammas, H.J. (2024). ZEISS IOLMaster 700. Intraocular Lens Calculations, Springer International Publishing.","DOI":"10.1007\/978-3-031-50666-6"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1007\/s00417-016-3473-0","article-title":"Intracameral cefuroxime in the prevention of postoperative endophthalmitis: An experience from Hong Kong","volume":"254","author":"Ng","year":"2016","journal-title":"Graefe\u2019s Arch. Clin. Exp. Ophthalmol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s00417-008-0926-0","article-title":"Resolving the clinical acuity categories \u201chand motion\u201d and \u201ccounting fingers\u201d using the Freiburg Visual Acuity Test (FrACT)","volume":"247","author":"Lange","year":"2009","journal-title":"Graefe\u2019s Arch. Clin. Exp. Ophthalmol."},{"key":"ref_27","first-page":"330","article-title":"IOL Power Calculation in Short and Long Eyes","volume":"6","author":"Hoffer","year":"2017","journal-title":"Asia-Pac. J. Ophthalmol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"2613","DOI":"10.1007\/s10792-023-02660-y","article-title":"Accuracy of 10 IOL power calculation formulas in 100 short eyes (\u226422 mm)","volume":"43","author":"Vilaltella","year":"2023","journal-title":"Int. Ophthalmol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"201","DOI":"10.4274\/tjo.galenos.2021.83704","article-title":"Effectiveness, Sensitivity, and Specificity of Intraocular Lens Power Calculation Formulas for Short Eyes","volume":"52","author":"Stopyra","year":"2022","journal-title":"Turk. J. Ophthalmol."},{"key":"ref_30","first-page":"2","article-title":"Assessment of the accuracy of new and updated intraocular lens power calculation formulas in 10\u2009930 eyes from the UK National Health Service","volume":"46","author":"Darcy","year":"2020","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.ophtha.2017.08.027","article-title":"Accuracy of Intraocular Lens Calculation Formulas","volume":"125","author":"Melles","year":"2018","journal-title":"Ophthalmology"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"e94","DOI":"10.1016\/j.ophtha.2020.08.010","article-title":"Intraocular Lens Power Formulas, Biometry, and Intraoperative Aberrometry: A Review","volume":"128","author":"Kane","year":"2021","journal-title":"Ophthalmology"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1016\/j.jcrs.2015.10.008","article-title":"Cataract surgery in the small eye","volume":"41","author":"Hoffman","year":"2015","journal-title":"J. Cataract Refract. Surg."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/19\/5852\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:07:43Z","timestamp":1760112463000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/19\/5852"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,30]]},"references-count":33,"journal-issue":{"issue":"19","published-online":{"date-parts":[[2024,10]]}},"alternative-id":["jcm13195852"],"URL":"https:\/\/doi.org\/10.3390\/jcm13195852","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,30]]}}}