{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T22:39:03Z","timestamp":1780785543107,"version":"3.54.1"},"reference-count":85,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Endometriosis and hyperprolactinaemia are conditions that might lead to infertility as a consequence. The aim of this article was to present the current knowledge about possible relationships between prolactin\/hyperprolactinaemia and endometriosis-related infertility. Experimental studies on local prolactin acting as cytokine and relationship of prolactin and endometriotic tissue, as well as clinical studies on hyperprolactinaemia and endometriosis-related infertility suggest the possible role of prolactin in endometriosis-related infertility, but final proof is still missing and the exact pathogenesis of infertility in such cases is still under investigation. Novel strategies in the treatment of endometriosis-related infertility, based on its connection with prolactin such as the use of prolactin receptor antibodies and prolactin receptor antagonists, are under investigation, but adequate clinical studies have yet to be undertaken.<\/jats:p>","DOI":"10.3390\/jcm13195868","type":"journal-article","created":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T07:41:49Z","timestamp":1727768509000},"page":"5868","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Prolactin and Hyperprolactinaemia in Endometriosis-Related Infertility: Are There Clinically Significant Connections?"],"prefix":"10.3390","volume":"13","author":[{"given":"Ranko","family":"Kutlesic","sequence":"first","affiliation":[{"name":"Department of Gynaecology and Obstetrics, Faculty of Medicine, University of Nis, 18000 Nis, Serbia"},{"name":"Clinic of Gynaecology and Obstetrics, University Clinical Centre Nis, 18000 Nis, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marija","family":"Kutlesic","sequence":"additional","affiliation":[{"name":"Clinic of Gynaecology and Obstetrics, University Clinical Centre Nis, 18000 Nis, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9197-4916","authenticated-orcid":false,"given":"Jelena","family":"Milosevic-Stevanovic","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics, Faculty of Medicine, University of Nis, 18000 Nis, Serbia"},{"name":"Clinic of Gynaecology and Obstetrics, University Clinical Centre Nis, 18000 Nis, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Predrag","family":"Vukomanovic","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics, Faculty of Medicine, University of Nis, 18000 Nis, Serbia"},{"name":"Clinic of Gynaecology and Obstetrics, University Clinical Centre Nis, 18000 Nis, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milan","family":"Stefanovic","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics, Faculty of Medicine, University of Nis, 18000 Nis, Serbia"},{"name":"Clinic of Gynaecology and Obstetrics, University Clinical Centre Nis, 18000 Nis, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danka","family":"Mostic-Stanisic","sequence":"additional","affiliation":[{"name":"Institute of Gynaecology and Obstetrics Belgrade, University Clinical Centre of Serbia, 11000 Belgrade, Serbia"},{"name":"Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1093\/humrep\/dew085","article-title":"A prospective cohort study of endometriosis and subsequent risk of infertility","volume":"31","author":"Prescott","year":"2016","journal-title":"Hum. 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