{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:33:58Z","timestamp":1760146438009,"version":"build-2065373602"},"reference-count":18,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T00:00:00Z","timestamp":1730851200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: Type A aortic dissection repair using Polytetrafluorethylene (PTFE) felt inlay and tissue glue has been proposed as a treatment modality. It remains unclear, if this method performs superiorly to tissue glue only. Methods: Between January 2011 and December 2015, 139 patients underwent surgical repair for type A aortic dissection, and 48 patients were excluded (n = 29 after receiving a composite graft, n = 18 in which no tissue glue was used, and n = 1 due to missing data). In the remaining patients, proximal aortic repair was performed either using PTFE felt inlay and tissue glue or tissue glue only. We analyzed the need for repeated surgery on the aorta during follow-up as a primary endpoint. The secondary endpoint was all-cause mortality at follow-up. Inverse probability of treatment weighting was used to balance the distribution of measured baseline covariates. Results: Sixty-six patients (73%) were treated with a tissue-glue-only approach\u2014the Control Group. Twenty-five patients (27%) underwent proximal PTFE felt inlay and tissue glue\u2014the Intervention Group. In the Intervention Group, 40% (n = 10) underwent reoperation due to re-dissection or pseudoaneurysm vs. 12% (n = 8) in the Control Group. The felt inlay increased the hazard of re-operation by 8.38 (1.63 to 43.0) after IPTW with death modeled as competing risk. Conclusions: Reoperation due to aortic complications was 10 times higher in patients treated with a combination of gluing and PTFE felt inlay vs. gluing only. These results are potentially caused by an interaction of PTFE, tissue glue, and aortic tissue.<\/jats:p>","DOI":"10.3390\/jcm13226663","type":"journal-article","created":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T06:27:39Z","timestamp":1730874459000},"page":"6663","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Polytetrafluoroethylene Felt Inlay Neomedia and Tissue Glue Do Not Prevent Reoperation in Type A Aortic Dissection"],"prefix":"10.3390","volume":"13","author":[{"given":"Jules","family":"Miazza","sequence":"first","affiliation":[{"name":"Department of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Koechlin","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8123-0438","authenticated-orcid":false,"given":"Brigitta","family":"Gahl","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland"},{"name":"Surgical Outcome Research Centre Basel, University Hospital Basel, University of Basel, 4056 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denis","family":"Berdajs","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luise","family":"V\u00f6hringer","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Friedrich","family":"Eckstein","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1386-0686","authenticated-orcid":false,"given":"Oliver","family":"Reuthebuch","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2537","DOI":"10.1001\/jama.1990.03450190069031","article-title":"The Diagnosis and Management of Aortic Dissection","volume":"264","author":"Crawford","year":"1990","journal-title":"JAMA"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.athoracsur.2015.03.102","article-title":"Bicuspid Aortic Valve Resuspension in Acute Type A Aortic Dissection Patients","volume":"100","author":"Rylski","year":"2015","journal-title":"Ann. 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Dis."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/S0003-4975(01)02777-1","article-title":"Role of Biologic Glue Repair of Proximal Aortic Dissection in the Development of Early and Midterm Redissection of the Aortic Root","volume":"72","author":"Kazui","year":"2001","journal-title":"Ann. Thorac. 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