{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T02:11:28Z","timestamp":1793239888842,"version":"4.5.0"},"reference-count":27,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T00:00:00Z","timestamp":1731283200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Lumbar spinal stenosis is a common degenerative condition, especially in older adults, leading to significant morbidity. Age, gender, and lumbar level variations in spinal canal width are critical in assessing stenosis risk. Many patients exhibit radiographic narrowing without clinical symptoms. This study analyzed the risk of lumbar stenosis by age, gender, and lumbar levels (L1-S1) using the MRI of patients without clinical signs of narrowing. Materials and Methods: This retrospective study included 120 patients, aged 20 to 75, who underwent lumbar MRI for unrelated reasons. Spinal canal widths were measured at five lumbar levels (L1-2 to L5-S1), and stenosis risk was classified as low, borderline, or high based on narrowing thresholds. Data were grouped by age and gender to assess the stenosis risk distribution. Results: The analysis revealed a progressive increase in stenosis risk from the upper to lower lumbar levels. At L4-5 and L5-S1, females aged 61\u201375 exhibited the highest proportions in borderline- and high-risk categories. While most patients were classified as low risk, many older patients showed radiographic narrowing without clinical symptoms. Males generally had wider canals and lower risk. Conclusions: Age and gender significantly impact lumbar stenosis risk, particularly in older females. The findings highlight the importance of clinical correlation despite radiographic evidence of stenosis and suggest potential for AI-based detection systems in enhancing assessments of spinal canal narrowing.<\/jats:p>","DOI":"10.3390\/jcm13226775","type":"journal-article","created":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T11:34:11Z","timestamp":1731324851000},"page":"6775","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Exploring Variations in Lumbar Canal Width: An MRI Study on Asymptomatic Patients by Age and Gender"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7793-7887","authenticated-orcid":false,"given":"Bet\u00fcl Tiryaki","family":"Ba\u015ftu\u011f","sequence":"first","affiliation":[{"name":"Radiology Department, Bilecik \u015eeyh Edebali University Medical Faculty, 11000 Bilecik, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,11]]},"reference":[{"key":"ref_1","unstructured":"De Sai, C., Reddy, V., and Agarwal, A. (2023, August 08). Anatomy, Back, Vertebral Column, StatPearls, Available online: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK525969."},{"key":"ref_2","unstructured":"Harrow-Mortelliti, M., Reddy, V., and Jimsheleishvili, G. (2023, March 17). Physiology, Spinal Cord, StatPearls, Available online: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK544267."},{"key":"ref_3","unstructured":"Munakomi, S., Foris, L.A., and Varacallo, M. (2023, August 13). Spinal Stenosis and Neurogenic Claudication, StatPearls, Available online: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK430872."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"S32","DOI":"10.1093\/pm\/pnz161","article-title":"A Review of Lumbar Spinal Stenosis with Intermittent Neurogenic Claudication: Disease and Diagnosis","volume":"20","author":"Deer","year":"2019","journal-title":"Pain Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"335","DOI":"10.2174\/1874325001105010335","article-title":"Pathophysiology and biomechanics of the aging spine","volume":"5","author":"Papadakis","year":"2011","journal-title":"Open Orthop. J."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"e1186","DOI":"10.5435\/JAAOS-D-24-00425","article-title":"Anatomic Parameters for Diagnosing Congenital Lumbar Stenosis Based on Computed Tomography of 1000 Patients","volume":"32","author":"Shin","year":"2024","journal-title":"J. Am. Acad. Orthop. Surg."},{"key":"ref_7","first-page":"e48747","article-title":"Applications of Interpedicular Distance and Anteroposterior Diameter in the Approximation of the Spinal Canal Area","volume":"15","author":"Brandt","year":"2023","journal-title":"Cureus"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"789","DOI":"10.31616\/asj.2022.0366","article-title":"Lumbar Spinal Stenosis: Review Update 2022","volume":"16","author":"Kwon","year":"2022","journal-title":"Asian Spine J."},{"key":"ref_9","unstructured":"Wu, L., Munakomi, S., and Cruz, R. (2024). Lumbar Spinal Stenosis. StatPearls, StatPearls Publishing."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.4103\/NRR.NRR-D-24-00311","article-title":"Dendritic spine degeneration: A primary mechanism in the aging process","volume":"20","author":"Flores","year":"2025","journal-title":"Neural Regen. Res."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1007\/s43390-024-00913-z","article-title":"Low bone mineral density: A primer for the spine surgeon","volume":"12","author":"Raad","year":"2024","journal-title":"Spine Deform."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"200","DOI":"10.5455\/aim.2023.31.200-205","article-title":"Morphometric Study of Lumbar Spinal Canal Dimensions in Bosnia and Herzegovina Population","volume":"31","author":"Cizmic","year":"2023","journal-title":"Acta Inform. Med."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"h6234","DOI":"10.1136\/bmj.h6234","article-title":"Management of lumbar spinal stenosis","volume":"352","author":"Lurie","year":"2016","journal-title":"BMJ"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/jmri.28067","article-title":"Magnetic Resonance Imaging Versus Computed Tomography for Three-Dimensional Bone Imaging of Musculoskeletal Pathologies: A Review","volume":"56","author":"Florkow","year":"2022","journal-title":"J. Magn. Reason. Imaging"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"671","DOI":"10.21037\/qims.2016.12.17","article-title":"Population reference range for developmental lumbar spinal canal size","volume":"6","author":"Griffith","year":"2016","journal-title":"Quant. Imaging Med. Surg."},{"key":"ref_16","unstructured":"Appeadu, M.K., and Bordoni, B. (2023, June 04). Falls and Fall Prevention in Older Adults, StatPearls, Available online: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK560761."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Ulmar, B., W\u00f6lfle-Roos, J., Kocak, T., and Brunner, A. (2019). Evaluation criteria for the assessment of occupational diseases of the lumbar spine-how reliable are they?. BMC Musculoskelet. Disord., 20.","DOI":"10.1186\/s12891-019-2878-4"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"322","DOI":"10.4184\/asj.2013.7.4.322","article-title":"Lumbar disc degenerative disease: Disc degeneration symptoms and magnetic resonance image findings","volume":"7","author":"Saleem","year":"2013","journal-title":"Asian Spine J."},{"key":"ref_19","first-page":"E715","article-title":"Gender difference of symptom severity in lumbar spinal stenosis: Role of pain sensitivity","volume":"16","author":"Kim","year":"2013","journal-title":"Pain Physician"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"483","DOI":"10.2147\/TCRM.S156364","article-title":"Predictive factors of symptomatic lumbar canal stenosis in patients after surgery for cervical spondylotic myelopathy","volume":"14","author":"Kong","year":"2018","journal-title":"Ther. Clin. Risk Manag."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"3804","DOI":"10.1038\/s41598-023-30928-x","article-title":"Ligamentum flavum analysis in patients with lumbar discus hernia and lumbar spinal stenosis","volume":"13","year":"2023","journal-title":"Sci Rep."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"71","DOI":"10.4184\/asj.2017.11.1.71","article-title":"Histopathological Analysis of Ligamentum Flavum in Lumbar Spinal Stenosis and Disc Herniation","volume":"11","author":"Altun","year":"2017","journal-title":"Asian Spine J."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.2522\/ptj.20120379","article-title":"Physical therapy interventions for degenerative lumbar spinal stenosis: A systematic review","volume":"93","author":"Macedo","year":"2013","journal-title":"Phys. Ther."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1016\/j.apmr.2021.03.033","article-title":"Effectiveness of Conservative Nonpharmacologic Therapies for Pain, Disability, Physical Capacity, and Physical Activity Behavior in Patients With Degenerative Lumbar Spinal Stenosis: A Systematic Review and Meta-Analysis","volume":"102","author":"Jacobi","year":"2021","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Cui, Y., Zhu, J., Duan, Z., Liao, Z., Wang, S., and Liu, W. (2022). Artificial Intelligence in Spinal Imaging: Current Status and Future Directions. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph191811708"},{"key":"ref_26","first-page":"e60055","article-title":"Sex Differences in Appendicitis: A Systematic Review","volume":"16","author":"Kollias","year":"2024","journal-title":"Cureus"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.jacr.2017.12.026","article-title":"Artificial Intelligence and Machine Learning in Radiology: Opportunities, Challenges, Pitfalls, and Criteria for Success","volume":"15 Pt B","author":"Thrall","year":"2018","journal-title":"J. Am. Coll. Radiol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/22\/6775\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:30:09Z","timestamp":1760113809000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/22\/6775"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,11]]},"references-count":27,"journal-issue":{"issue":"22","published-online":{"date-parts":[[2024,11]]}},"alternative-id":["jcm13226775"],"URL":"https:\/\/doi.org\/10.3390\/jcm13226775","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,11]]}}}