{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:34:56Z","timestamp":1760146496394,"version":"build-2065373602"},"reference-count":34,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T00:00:00Z","timestamp":1731283200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Purpose: To investigate intraretinal changes and central millimeter thickness (CMMT) after successful uncomplicated cataract surgery in patients with asymptomatic epiretinal membrane (ERM). Design: prospective, single-center, interventional case series. Methods: Thirty eyes from 26 patients with cataract and ERM (ERM group) and fifteen consecutive eyes with senile cataract with a healthy macula (control group) were included. Best-corrected visual acuity (BCVA) and optical coherence tomography (OCT) as well as biomicroscopy were performed at baseline, one week, one month and three months after cataract surgery. OCT raster scans were further analyzed regarding CMMT and structural changes in the retinal morphology. Results: The baseline mean visual acuity improved significantly three months after cataract surgery in both groups (p &lt; 0.05). CMMT in the ERM group was 342 (\u00b153 \u03bcm) at baseline and increased significantly to 356 (\u00b157) \u03bcm after three months (p &lt; 0.05). One patient in the ERM group developed temporary cystoid macular edema one week after cataract surgery that resolved under topical treatment within three months. CMMT in the control group increased significantly three months after cataract surgery as well but no structural changes in the retinal morphology were observed in this group. Conclusions: This study provides evidence that cataract surgery in eyes with asymptomatic pre-existing ERM can be considered as safe and effective, resulting in good visual acuity outcomes. However, an increase in CMMT and temporary mild changes in retinal morphology may occur.<\/jats:p>","DOI":"10.3390\/jcm13226781","type":"journal-article","created":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T06:28:32Z","timestamp":1731392912000},"page":"6781","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Retinal Thickness Change Following Cataract Surgery in Eyes with Epiretinal Membranes"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0986-2163","authenticated-orcid":false,"given":"Barbara","family":"Wienerroither","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Academic Teaching Hospital of Saint John of God, Johannes von Gott Platz 1, 1020 Vienna, Austria"},{"name":"Sigmund Freud University Vienna, Campus Prater, Freudplatz 1, 1020 Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgios","family":"Mylonas","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Academic Teaching Hospital of Saint John of God, Johannes von Gott Platz 1, 1020 Vienna, Austria"},{"name":"Department of Ophthalmology, Medical University of Vienna, W\u00e4hringer G\u00fcrtel 18-20, 1090 Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clemens","family":"Bernhart","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Academic Teaching Hospital of Saint John of God, Johannes von Gott Platz 1, 1020 Vienna, Austria"},{"name":"Sigmund Freud University Vienna, Campus Prater, Freudplatz 1, 1020 Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franz","family":"Prager","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Academic Teaching Hospital of Saint John of God, Johannes von Gott Platz 1, 1020 Vienna, Austria"},{"name":"Sigmund Freud University Vienna, Campus Prater, Freudplatz 1, 1020 Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guenal","family":"Kahraman","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Academic Teaching Hospital of Saint John of God, Johannes von Gott Platz 1, 1020 Vienna, Austria"},{"name":"Sigmund Freud University Vienna, Campus Prater, Freudplatz 1, 1020 Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Amon","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Academic Teaching Hospital of Saint John of God, Johannes von Gott Platz 1, 1020 Vienna, Austria"},{"name":"Sigmund Freud University Vienna, Campus Prater, Freudplatz 1, 1020 Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1136\/bjophthalmol-2011-300539","article-title":"Global estimates of visual impairment: 2010","volume":"96","author":"Pascolini","year":"2012","journal-title":"Br. J. Ophthalmol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"241","DOI":"10.5935\/0004-2749.20150062","article-title":"Optical coherence tomography in patients undergoing cataract surgery","volume":"78","author":"Moreira","year":"2015","journal-title":"Arq. Bras. Oftalmol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/j.ophtha.2014.10.014","article-title":"The epidemiology of vitreoretinal interface abnormalities as detected by spectral-domain optical coherence tomography: The beaver dam eye study","volume":"122","author":"Meuer","year":"2015","journal-title":"Ophthalmology"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/0002-9394(75)90605-4","article-title":"Clinical features of idiopathic preretinal macular fibrosis. Schoenberg Lecture","volume":"79","author":"Wise","year":"1975","journal-title":"Am. J. Ophthalmol."},{"key":"ref_5","first-page":"416","article-title":"Vitreoretinal juncture; epiretinal membranes and vitreous","volume":"16","author":"Foos","year":"1977","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1038\/eye.2008.161","article-title":"Influence of phacoemulsification surgery on progression of idiopathic epiretinal membrane","volume":"23","author":"Hayashi","year":"2009","journal-title":"Eye"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/0002-9394(53)90302-X","article-title":"A newly defined vitreous syndrome following cataract surgery","volume":"36","author":"Irvine","year":"1953","journal-title":"Am. J. Ophthalmol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1016\/j.ophtha.2015.05.014","article-title":"Topical Nonsteroidal Anti-inflammatory Drugs and Cataract Surgery: A Report by the American Academy of Ophthalmology","volume":"122","author":"Kim","year":"2015","journal-title":"Ophthalmology"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1016\/j.ophtha.2014.04.035","article-title":"Post-cataract prevention of inflammation and macular edema by steroid and nonsteroidal anti-inflammatory eye drops: A systematic review","volume":"121","author":"Kessel","year":"2014","journal-title":"Ophthalmology"},{"key":"ref_10","first-page":"557","article-title":"The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery","volume":"96","author":"Flach","year":"1998","journal-title":"Trans. Am. Ophthalmol. Soc."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/0039-6257(84)90226-1","article-title":"Cystoid macular edema in pseudophakia","volume":"28","author":"Stark","year":"1984","journal-title":"Surv. Ophthalmol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1097\/ICU.0b013e32834cd5f8","article-title":"Pseudophakic cystoid macular edema","volume":"23","author":"Yonekawa","year":"2012","journal-title":"Curr. Opin. Ophthalmol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1159\/000331277","article-title":"Pseudophakic cystoid macular edema","volume":"227","author":"Lobo","year":"2012","journal-title":"Ophthalmologica"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1080\/02713680601160610","article-title":"Evaluation of Macular Changes After Uncomplicated Phacoemulsification Surgery by Optical Co-herence Tomography","volume":"32","author":"Perente","year":"2007","journal-title":"Curr. Eye Res."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s00508-015-0702-1","article-title":"Influence of cataract surgery on macular thickness: A 6-month follow-up","volume":"127","author":"Knez","year":"2015","journal-title":"Wien. Klin. Wochenschr."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Ikegami, Y., Takahashi, M., and Amino, K. (2020). Evaluation of choroidal thickness, macular thickness, and aqueous flare after cataract surgery in patients with and without diabetes: A prospective randomized study. BMC Ophthalmol., 20.","DOI":"10.1186\/s12886-020-01371-7"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"e266","DOI":"10.1016\/j.surge.2021.07.005","article-title":"Changes in choroidal and foveal retinal thickness after cataract surgery: Our results","volume":"20","author":"Akcam","year":"2022","journal-title":"Surgeon"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/S0886-3350(99)80136-9","article-title":"Optical coherence tomography of macularthickness after cataract surgery","volume":"25","author":"Sourdille","year":"1999","journal-title":"J. Cataract. Refract. Surg."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1038\/sj.eye.6702460","article-title":"Change of foveal and perifoveal thickness measured by OCT after phacoemulsification and IOL implantation","volume":"22","author":"Biro","year":"2008","journal-title":"Eye"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1097\/00006982-198808030-00001","article-title":"Cystoid macular edema following extracapsular cataract extraction and posterior chamber intraocular lens implantation","volume":"8","author":"Bradford","year":"1988","journal-title":"Retina"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1016\/S0161-6420(96)30465-X","article-title":"Risk factors for retinal detachment after cataract surgery. A population-based case-control study","volume":"103","author":"Tielsch","year":"1996","journal-title":"Ophthalmology"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1016\/j.jcrs.2003.12.024","article-title":"Phacoemulsification after retinal detachment surgery","volume":"30","author":"Igarashi","year":"2004","journal-title":"J. Cataract. Refract. Surg."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"327","DOI":"10.3109\/02713683.2011.635402","article-title":"Evaluation of cystoid macular edema using optical coherence tomography and fundus fluorescein angiography after uncomplicated phacoemulsification surgery","volume":"37","author":"Kusbeci","year":"2012","journal-title":"Curr. Eye Res."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1007\/BF00158291","article-title":"Immunohistochemical localization of blood-retinal barrier breakdown sites associated with post-surgical macular oedema","volume":"26","author":"Vinores","year":"1994","journal-title":"Histochem. J."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"751","DOI":"10.5301\/ejo.5000280","article-title":"Evaluation of macular thickness after uncomplicated cataract surgery using optical coherence tomography","volume":"23","author":"Giansanti","year":"2013","journal-title":"Eur. J. Ophthalmol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1159\/000336908","article-title":"Prospective study of foveal thickness alterations after cataract surgery assessed by optical coherence tomography","volume":"228","author":"Tsilimbaris","year":"2012","journal-title":"Ophthalmologica"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1038\/eye.1995.104","article-title":"Vitreous loss in planned extracapsular cataract extraction does lead to a poorer visual outcome","volume":"9","author":"Frost","year":"1995","journal-title":"Eye"},{"key":"ref_28","first-page":"127","article-title":"Repercussions of cataract surgery on the development of cystoid macular edema in the diabetic patient","volume":"256","author":"Bonnet","year":"1995","journal-title":"Bull. Soc. Belg. Ophtalmol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1016\/S0161-6420(92)31818-4","article-title":"Extracapsular cataract extraction and posterior chamber intraocular lens implantation in uveitis patients","volume":"99","author":"Foster","year":"1992","journal-title":"Ophthalmology"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.ajo.2012.07.013","article-title":"Macular edema following cataract surgery in eyes with previous 23-gauge vitrectomy and peeling of the internal limiting membrane","volume":"155","author":"Mylonas","year":"2013","journal-title":"Am. J. Ophthalmol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1016\/j.jcrs.2007.05.013","article-title":"Clinical pseudophakic cystoid macular edema. Risk factors for development and duration after treatment","volume":"33","author":"Henderson","year":"2007","journal-title":"J. Cataract. Refract. Surg."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.ophtha.2015.10.001","article-title":"Risk Factors and Incidence of Macular Edema after Cataract Surgery: A Database Study of 81984 Eyes","volume":"123","author":"Chu","year":"2016","journal-title":"Ophthalmology"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1038\/sj.eye.6701864","article-title":"Cystoid macular oedema and changes in retinal thickness after phacoemulsification with optical coherence tomography","volume":"20","author":"Ching","year":"2006","journal-title":"Eye"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1136\/bjo.2004.097022","article-title":"Influence of cataract on optical coherence tomography image quality and retinal thickness","volume":"90","author":"Faber","year":"2006","journal-title":"Br. J. Ophthalmol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/22\/6781\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:30:17Z","timestamp":1760113817000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/22\/6781"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,11]]},"references-count":34,"journal-issue":{"issue":"22","published-online":{"date-parts":[[2024,11]]}},"alternative-id":["jcm13226781"],"URL":"https:\/\/doi.org\/10.3390\/jcm13226781","relation":{},"ISSN":["2077-0383"],"issn-type":[{"type":"electronic","value":"2077-0383"}],"subject":[],"published":{"date-parts":[[2024,11,11]]}}}