{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T17:48:01Z","timestamp":1792259281778,"version":"4.4.0"},"reference-count":237,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T00:00:00Z","timestamp":1731628800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: The extensive range of instruments designed for evaluating functional performance (FP) in chronic respiratory diseases (CRD) other than chronic obstructive pulmonary disease (COPD) presents a challenge in selecting the most appropriate one. Therefore, this systematic review aimed to summarise FP instruments, their measurement properties, their minimum clinically important differences, and their associations with CRD course-related events or prognosis in non-COPD CRD. Methods: Studies employing patient-reported or performance-based instruments to assess FP in non-COPD CRD were systematically identified in the PubMed, PEDro, Embase, and Cochrane Library databases. COPD-exclusive studies or those solely reporting exercise capacity tests were excluded. Examination focused on measurement properties and associations with CRD course-related events or prognosis. The risk of bias was evaluated using the COSMIN, Downs and Black, and PEDro checklists based on the study design. Results: A total of 216 studies across seven CRD categories [asthma, bronchiectasis, cystic fibrosis, interstitial lung disease (ILD), pulmonary arterial hypertension (PAH), pre-\/post-lung-transplantation] from various study types were included. Thirty-three instruments were identified, with the SF-36 questionnaire\u2019s physical function domain being the most commonly used patient-reported tool. The 1 min sit-to-stand test was the most extensively studied performance-based measure, with its measurement properties frequently reported in non-COPD CRD studies. Associations with events were infrequently documented, primarily in ILD and PAH studies related to mortality. Conclusions: Despite the prevalent use of FP instruments, limited information exists concerning their measurement properties and clinical implications. This review furnishes a concise summary of available evidence, aiding informed clinical decisions when selecting FP tools for non-COPD CRD.<\/jats:p>","DOI":"10.3390\/jcm13226887","type":"journal-article","created":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T09:30:25Z","timestamp":1732008625000},"page":"6887","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Functional Measures in Non-COPD Chronic Respiratory Diseases: A Systematic Review"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7283-4934","authenticated-orcid":false,"given":"Camile Ludovico","family":"Zamboti","sequence":"first","affiliation":[{"name":"Laboratory of Research in Respiratory Physiotherapy (LFIP), Department of Physiotherapy, Londrina State University (UEL), Londrina 86038-3500, Brazil"},{"name":"Department of Physiotherapy, Faculty of Science and Technology, S\u00e3o Paulo State University (UNESP), Presidente Prudente 19060-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heloise Ang\u00e9lico","family":"Pimp\u00e3o","sequence":"additional","affiliation":[{"name":"Laboratory of Research in Respiratory Physiotherapy (LFIP), Department of Physiotherapy, Londrina State University (UEL), Londrina 86038-3500, Brazil"},{"name":"Department of Physiotherapy, Faculty of Science and Technology, S\u00e3o Paulo State University (UNESP), Presidente Prudente 19060-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9755-6432","authenticated-orcid":false,"given":"Larissa Dragonetti","family":"Bertin","sequence":"additional","affiliation":[{"name":"Laboratory of Research in Respiratory Physiotherapy (LFIP), Department of Physiotherapy, Londrina State University (UEL), Londrina 86038-3500, Brazil"},{"name":"Research Center in Health Sciences, University Pit\u00e1goras UNOPAR, Londrina 86038-3500, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2490-8980","authenticated-orcid":false,"given":"Gabriela Garcia","family":"Krinski","sequence":"additional","affiliation":[{"name":"Laboratory of Research in Respiratory Physiotherapy (LFIP), Department of Physiotherapy, Londrina State University (UEL), Londrina 86038-3500, Brazil"},{"name":"Research Center in Health Sciences, University Pit\u00e1goras UNOPAR, Londrina 86038-3500, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tathielle","family":"Garcia","sequence":"additional","affiliation":[{"name":"Laboratory of Research in Respiratory Physiotherapy (LFIP), Department of Physiotherapy, Londrina State University (UEL), Londrina 86038-3500, Brazil"},{"name":"Department of Physiotherapy, Faculty of Science and Technology, S\u00e3o Paulo State University (UNESP), Presidente Prudente 19060-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3925-0771","authenticated-orcid":false,"given":"Sandro Laerth Souza","family":"dos Santos Filho","sequence":"additional","affiliation":[{"name":"Research Center in Health Sciences, University Pit\u00e1goras UNOPAR, Londrina 86038-3500, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8620-7499","authenticated-orcid":false,"given":"Vinicius","family":"Cavalheri","sequence":"additional","affiliation":[{"name":"Curtin School of Allied Health, Faculty of Health Sciences, Curtin University, Perth, WA 6102, Australia"},{"name":"Allied Health, South Metropolitan Health Service, Perth 6150, Australia"},{"name":"Exercise Medicine Research Institute, Edith Cowan University, Perth 6027, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3369-6660","authenticated-orcid":false,"given":"Fabio","family":"Pitta","sequence":"additional","affiliation":[{"name":"Laboratory of Research in Respiratory Physiotherapy (LFIP), Department of Physiotherapy, Londrina State University (UEL), Londrina 86038-3500, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7648-8573","authenticated-orcid":false,"given":"Carlos Augusto","family":"Camillo","sequence":"additional","affiliation":[{"name":"Laboratory of Research in Respiratory Physiotherapy (LFIP), Department of Physiotherapy, Londrina State University (UEL), Londrina 86038-3500, Brazil"},{"name":"Department of Physiotherapy, Faculty of Science and Technology, S\u00e3o Paulo State University (UNESP), Presidente Prudente 19060-900, Brazil"},{"name":"Research Center in Health Sciences, University Pit\u00e1goras UNOPAR, Londrina 86038-3500, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/j.1398-9995.2007.01307.x","article-title":"Global alliance against chronic respiratory diseases","volume":"62","author":"Bousquet","year":"2007","journal-title":"Allergy"},{"key":"ref_2","unstructured":"Global Initative for Chronic Obstructive Lung Disease (GOLD) (2024, November 05). 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