{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T02:47:04Z","timestamp":1784515624687,"version":"3.55.0"},"reference-count":11,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T00:00:00Z","timestamp":1732147200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Heidelberg University"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: Cage implantation decompresses neural elements, stabilizes segments, and promotes fusion, with sagittal balance influenced by cage size, geometry, and position. This retrospective study compared the effects of lumbar interbody cages with 10\u00b0 and 15\u00b0 lordotic angles on global and segmental lordosis in patients undergoing transforaminal lumbar interbody fusion (TLIF). Methods: Data from 215 patients who underwent 259 TLIF procedures between 2018 and 2022 were analyzed. All the surgeries were performed by a single senior orthopedic spine surgeon, and cages were selected by the surgeon based on patients\u2019 clinical and anatomical factors. Radiographic assessments included measurements of global and segmental lordosis. Results: Patients who received 15\u00b0 cages demonstrated significantly greater segmental lordosis compared to those who received 10\u00b0 cages in both bisegmental and monosegmental procedures (p &lt; 0.001). While the global lordosis in the 10\u00b0-cage group remained unchanged postoperatively (p = 0.687), bisegmental procedures showed a small but statistically significant increase (p = 0.035). Moreover, global lordosis did not significantly differ between the 10\u00b0- and 15\u00b0-cage groups. Conclusions: Cage geometry significantly influenced segmental lordosis, with 15\u00b0 cages achieving overall more superior radiographic results compared to 10\u00b0 cages. However, global lordosis was unaffected by cage angle, thereby highlighting the multifaceted nature of factors that influence overall spinal alignment. These findings provide valuable insights into lumbar spine surgery, thus emphasizing the need for comprehensive preoperative planning and consideration of individual patient characteristics.<\/jats:p>","DOI":"10.3390\/jcm13237012","type":"journal-article","created":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T06:57:54Z","timestamp":1732172274000},"page":"7012","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Influence of a Lordotic Cage Profile on Global and Segmental Lordosis in the Context of Lumbar TLIF Surgeries: A Retrospective Radiological Analysis"],"prefix":"10.3390","volume":"13","author":[{"given":"Steffen","family":"Schulz","sequence":"first","affiliation":[{"name":"Orthopedic Trauma Surgery Center, University Medical Center Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Fennema","sequence":"additional","affiliation":[{"name":"AMR Advanced Medical Research, 8708 M\u00e4nnedorf, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9463-9638","authenticated-orcid":false,"given":"Ali","family":"Darwich","sequence":"additional","affiliation":[{"name":"Orthopedic Trauma Surgery Center, University Medical Center Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederic","family":"Bludau","sequence":"additional","affiliation":[{"name":"Orthopedic Trauma Surgery Center, University Medical Center Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Rickert","sequence":"additional","affiliation":[{"name":"Orthop\u00e4die Rickert, 63500 Seligenstadt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/s00586-020-06596-0","article-title":"Lumbar interbody fusion: Recent advances in surgical techniques and bone healing strategies","volume":"30","author":"Meng","year":"2021","journal-title":"Eur. Spine J."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1186\/s13018-020-01866-5","article-title":"Can posterior stand-alone expandable cages safely restore lumbar lordosis? A minimum 5-year follow-up study","volume":"15","author":"Kim","year":"2020","journal-title":"J. Orthop. Surg. Res."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"2024","DOI":"10.1097\/01.brs.0000179086.30449.96","article-title":"The impact of positive sagittal balance in adult spinal deformity","volume":"30","author":"Glassman","year":"2005","journal-title":"Spine"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1007\/s00586-011-2124-8","article-title":"Influence of transforaminal lumbar interbody fusion procedures on spinal and pelvic parameters of sagittal balance","volume":"21","author":"Lenoir","year":"2012","journal-title":"Eur. Spine J."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1097\/01.BRS.0000083167.78853.D5","article-title":"Influence of cage geometry on sagittal alignment in instrumented posterior lumbar interbody fusion","volume":"28","author":"Fritsch","year":"2003","journal-title":"Spine"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.1097\/01.BRS.0000083181.25260.D6","article-title":"Management of fixed sagittal plane deformity: Outcome of combined anterior and posterior surgery","volume":"28","author":"Berven","year":"2003","journal-title":"Spine"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"419","DOI":"10.3171\/2020.12.SPINE201665","article-title":"Does transforaminal lumbar interbody fusion induce lordosis or kyphosis? Radiographic evaluation with a minimum 2-year follow-up","volume":"35","author":"Liu","year":"2021","journal-title":"J. Neurosurg. Spine"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"E17","DOI":"10.3171\/2020.6.FOCUS20393","article-title":"Does interbody cage lordosis impact actual segmental lordosis achieved in minimally invasive lumbar spine fusion?","volume":"49","author":"Lovecchio","year":"2020","journal-title":"Neurosurg. Focus"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"E674","DOI":"10.1097\/BSD.0000000000001334","article-title":"Does Interbody Cage Lordosis and Position Affect Radiographic Outcomes After Single-level Transforaminal Lumbar Interbody Fusion?","volume":"35","author":"DiMaria","year":"2022","journal-title":"Clin. 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Rep., 12.","DOI":"10.1038\/s41598-022-18679-7"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/23\/7012\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:36:32Z","timestamp":1760114192000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/23\/7012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,21]]},"references-count":11,"journal-issue":{"issue":"23","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["jcm13237012"],"URL":"https:\/\/doi.org\/10.3390\/jcm13237012","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,21]]}}}