{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T15:30:30Z","timestamp":1775575830756,"version":"3.50.1"},"reference-count":62,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T00:00:00Z","timestamp":1732752000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: Chronic low back pain (CLBP) is highly prevalent and relevant in all medical fields. This study evaluated the safety and effectiveness of interdisciplinary fascia therapy (IFT) for CLBP, focusing on its potential to reduce pain intensity, disability, and regulate autonomic nervous system (ANS) activity. Methods: Nine participants with CLBP each underwent nine sessions of IFT, twice weekly. The intervention involved a 12-grip manual sequence targeting deep paravertebral myofascial structures, complemented by heart rate variability (HRV) biofeedback training twice daily for 15 min. Pain and quality-of-life measures were assessed using the Brief Pain Inventory (BPI) questionnaire at baseline, mid-treatment (4th session), and post-treatment (9th session). HRV metrics were monitored with a 24 h ECG Holter device before and after the treatment period. Statistical analyses included paired t-tests, Wilcoxon signed-rank tests, and Cohen\u2019s d for effect size. Results: Significant reductions in pain levels were observed across all subjective BPI measures, including momentary, strongest, minimal, and average pain scores (p &lt; 0.001), with 83% and 87% reductions in pain intensity and disability, respectively. Quality-of-life indicators such as mood, sleep, and enjoyment of life showed significant improvements (p &lt; 0.001). While only one HRV metric (rMSSD) achieved statistical significance, other HRV measures indicated medium to large effect sizes, suggesting favorable trends in ANS regulation. Conclusions: IFT demonstrated significant effects on subjective BPI pain reduction and quality of life, alongside potential regulatory impacts on ANS activity in individuals with CLBP. These results support the use of IFT as an effective intervention for pain management in CLBP and ANS regulation, meriting further exploration.<\/jats:p>","DOI":"10.3390\/jcm13237226","type":"journal-article","created":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T07:28:01Z","timestamp":1732778881000},"page":"7226","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Interdisciplinary Fascia Therapy: A Proof-of-Concept Pilot Study for a New Myofascial Approach for Chronic Low Back Pain"],"prefix":"10.3390","volume":"13","author":[{"given":"Christopher M.","family":"Gordon","sequence":"first","affiliation":[{"name":"CIT Research Institute, 70597 Stuttgart, Germany"},{"name":"Fascia Research Group, Division of Neurophysiology, University of Ulm, 89081 Ulm, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"Dugan","sequence":"additional","affiliation":[{"name":"CIT Research Institute, 70597 Stuttgart, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"H\u00f6rmann","sequence":"additional","affiliation":[{"name":"CIT Research Institute, 70597 Stuttgart, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8652-948X","authenticated-orcid":false,"given":"Pedro","family":"Montoya","sequence":"additional","affiliation":[{"name":"Research Institute of Health Sciences (IUNICS), University of the Balearic Islands, 07122 Palma de Mallorca, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,28]]},"reference":[{"key":"ref_1","first-page":"176","article-title":"Abstracts of: Exercise and chronic low back pain: What works","volume":"107","author":"Liddle","year":"2004","journal-title":"J. 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