{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:50:53Z","timestamp":1787028653445,"version":"build-2736575974"},"reference-count":69,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T00:00:00Z","timestamp":1734652800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>The prompt and appropriate management of acute type A aortic dissections is imperative for patient survival. Advances in medical technology have broadened the adjuncts available to treat the spectrum of pathology within this population. The role of medical management prior to surgical intervention and the components of operative management, including cannulation strategies, neuroprotection, and the extent of aortic intervention, have been explored in-depth within the literature. More recent work has identified novel open and endovascular techniques available to treat acute type A dissections. This review aims to summarize the literature, with a particular focus on innovation in cardiac surgery and its role in the care of this high-risk population.<\/jats:p>","DOI":"10.3390\/jcm13247794","type":"journal-article","created":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T07:42:18Z","timestamp":1734680538000},"page":"7794","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Advances and Innovation in Acute Type a Aortic Dissection"],"prefix":"10.3390","volume":"13","author":[{"given":"Madison A.","family":"Grasty","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kendall","family":"Lawrence","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.21037\/jtd-20-2549","article-title":"Femoral arterial cannulation remains a safe and reliable option for aortic dissection repair","volume":"13","author":"Lemaire","year":"2021","journal-title":"J. Thorac. Dis."},{"key":"ref_2","first-page":"42","article-title":"Acute aortic dissection type A: Case series and insights on incidence, management and outcomes","volume":"25","author":"Tzikas","year":"2021","journal-title":"Hippokratia"},{"key":"ref_3","first-page":"217","article-title":"Dissecting aneurysm of the aorta: A review of 505 cases","volume":"37","author":"Hirst","year":"1958","journal-title":"Medicina"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1097\/HCO.0000000000000667","article-title":"Type A aortic dissection complicated by malperfusion syndrome","volume":"34","author":"Norton","year":"2019","journal-title":"Curr. Opin. Cardiol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1001\/jamacardio.2022.2718","article-title":"Early Mortality in Type A Acute Aortic Dissection: Insights from the International Registry of Acute Aortic Dissection","volume":"7","author":"Harris","year":"2022","journal-title":"JAMA Cardiol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.jtcvs.2004.09.005","article-title":"International Registry of Acute Aortic Dissection Investigators. Contemporary results of surgery in acute type A aortic dissection: The International Registry of Acute Aortic Dissection experience","volume":"129","author":"Trimarchi","year":"2005","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1001\/jama.283.7.897","article-title":"The International Registry of Acute Aortic Dissection (IRAD): New insights into an old disease","volume":"283","author":"Hagan","year":"2000","journal-title":"JAMA"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1016\/S0003-4975(00)01934-2","article-title":"Early and late surgical outcomes of acute type A aortic dissection in patients aged 75 years and older","volume":"70","author":"Kawahito","year":"2000","journal-title":"Ann. Thorac. Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.jtcvs.2021.04.053","article-title":"AATS Clinical Practice Standards Committee: Adult Cardiac Surgery. 2021 The American Association for Thoracic Surgery expert consensus document: Surgical treatment of acute type A aortic dissection","volume":"162","author":"Malaisrie","year":"2021","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1016\/j.athoracsur.2019.04.040","article-title":"Acute Type A Dissection Repair by High-Volume Vs Low-Volume Surgeons at a High-Volume Aortic Center","volume":"108","author":"Nissen","year":"2019","journal-title":"Ann. Thorac. Surg."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1016\/j.athoracsur.2013.02.039","article-title":"National outcomes in acute aortic dissection: Influence of surgeon and institutional volume on operative mortality","volume":"95","author":"Chikwe","year":"2013","journal-title":"Ann. Thorac. Surg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1016\/j.jacc.2013.10.085","article-title":"Outcomes of acute type a dissection repair before and after implementation of a multidisciplinary thoracic aortic surgery program","volume":"63","author":"Andersen","year":"2014","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1177\/2047487318764963","article-title":"Aortic centres should represent the standard of care for acute aortic syndrome","volume":"25","author":"Mariscalco","year":"2018","journal-title":"Eur. J. Prev. Cardiol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1161\/CIRCULATIONAHA.118.038867","article-title":"Interfacility Transfer of Medicare Beneficiaries With Acute Type A Aortic Dissection and Regionalization of Care in the United States","volume":"140","author":"Goldstone","year":"2019","journal-title":"Circulation"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.surg.2020.04.007","article-title":"Impact of center volume on outcomes of surgical repair for type A acute aortic dissections","volume":"169","author":"Dobaria","year":"2020","journal-title":"Surgery"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"194","DOI":"10.21037\/acs.2016.05.12","article-title":"The utility of the aortic dissection team: Outcomes and insights after a decade of experience","volume":"5","author":"Andersen","year":"2016","journal-title":"Ann. Cardiothorac. Surg."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.jtcvs.2017.02.015","article-title":"Acute type A aortic dissection in the United Kingdom: Surgeon volume-outcome relation","volume":"154","author":"Bashir","year":"2017","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.jtcvs.2015.03.023","article-title":"The impact of surgical strategy on survival after repair of type A aortic dissection","volume":"150","author":"Lawton","year":"2015","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1093\/ejcts\/ezv035","article-title":"Axillary versus femoral arterial cannulation in type A acute aortic dissection: Evidence from a meta-analysis of comparative studies and adjusted risk estimates","volume":"48","author":"Benedetto","year":"2015","journal-title":"Eur. J. Cardio-Thorac. Surg."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S1010-7940(03)00307-5","article-title":"Cannulation of the right axillary artery for surgery of acute type A aortic dissection","volume":"24","author":"Pasic","year":"2003","journal-title":"Eur. J. Cardio-Thorac. Surg."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.jtcvs.2006.09.059","article-title":"Central cannulation is safe in acute aortic dissection repair","volume":"132","author":"Reece","year":"2007","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.xjon.2023.01.017","article-title":"Central aortic versus axillary artery cannulation for aortic arch surgery","volume":"14","author":"Chung","year":"2023","journal-title":"JTCVS Open"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.hlc.2010.06.662","article-title":"An Australian experience with aortic arch replacement: A novel approach without circulatory arrest or deep hypothermia","volume":"20","author":"Matalanis","year":"2011","journal-title":"Heart Lung Circ."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1016\/j.athoracsur.2020.02.010","article-title":"Direct Aortic Versus Peripheral Arterial Cannulation in Surgery for Type A Aortic Dissection","volume":"110","author":"Jormalainen","year":"2010","journal-title":"Ann. Thorac. Surg."},{"key":"ref_25","first-page":"27","article-title":"Outcome after aortic, axillary, or femoral cannulation for acute type A aortic dissection","volume":"159","author":"Kreibich","year":"2018","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"2899","DOI":"10.1007\/s00268-023-07116-z","article-title":"Direct Aortic Versus Supra-Aortic Arterial Cannulation During Surgery for Acute Type A Aortic Dissection","volume":"47","author":"Juvonen","year":"2023","journal-title":"World J. Surg."},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Ustunisik, C.T., Yagci, L., Arapi, B., Balkanay, O.O., Omeroglu, S.N., Ipek, G., and Goksedef, D. (2024). Aortic versus axillary artery cannulation for hemiarch replacement: Single-centre real-world experience. BMC Cardiovasc. Disord., 24.","DOI":"10.1186\/s12872-024-04125-1"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.jtcvs.2012.07.072","article-title":"Effect of cerebral protection strategy on outcome of patients with Stanford type A aortic dissection","volume":"146","author":"Wiedemann","year":"2012","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1016\/j.athoracsur.2020.04.144","article-title":"Type-A Aortic Dissection and Cerebral Perfusion: The Society of Thoracic Surgeons Database Analysis","volume":"110","author":"McLarty","year":"2020","journal-title":"Ann. Thorac. Surg."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1053\/j.semtcvs.2019.01.001","article-title":"Optimal Cerebral Protection Strategies in Aortic Surgery","volume":"31","author":"Lou","year":"2019","journal-title":"Semin. Thorac. Cardiovasc. Surg."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"328","DOI":"10.21037\/acs.2016.04.02","article-title":"Comparison between antegrade and retrograde cerebral perfusion or profound hypothermia as brain protection strategies during repair of type A aortic dissection","volume":"5","author":"Stamou","year":"2016","journal-title":"Ann. Cardiothorac. Surg."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.21037\/jtd-23-1039","article-title":"Cerebral protection in acute type A aortic dissection surgery: A systematic review and meta-analysis","volume":"16","author":"Rahimi","year":"2024","journal-title":"J. Thorac. Dis."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.jtcvs.2019.02.045","article-title":"Cerebral protection strategies in aortic arch surgery: A network meta-analysis","volume":"159","author":"Hameed","year":"2020","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.jtcvs.2013.10.036","article-title":"Similar cerebral protective effectiveness of antegrade and retrograde cerebral perfusion combined with deep hypothermia circulatory arrest in aortic arch surgery: A meta-analysis and systematic review of 5060 patients","volume":"148","author":"Hu","year":"2014","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1053\/j.semtcvs.2020.06.025","article-title":"Contemporary Surgical Strategies for Acute Type A Aortic Dissection","volume":"32","author":"Frankel","year":"2020","journal-title":"Semin. Thorac. Cardiovasc. Surg."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.athoracsur.2013.07.034","article-title":"Impact of perfusion strategy on outcome after repair for acute type a aortic dissection","volume":"97","author":"Etz","year":"2014","journal-title":"Ann. Thorac. Surg."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1016\/j.athoracsur.2012.01.106","article-title":"What is the best strategy for brain protection in patients undergoing aortic arch surgery? A single center experience of 636 patients","volume":"93","author":"Misfeld","year":"2012","journal-title":"Ann. Thorac. Surg."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"S65","DOI":"10.1016\/j.jtcvs.2014.08.070","article-title":"A study of brain protection during total arch replacement comparing antegrade cerebral perfusion versus hypothermic circulatory arrest, with or without retrograde cerebral perfusion: Analysis based on the Japan Adult Cardiovascular Surgery Database","volume":"149","author":"Okita","year":"2015","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1161\/CIRCULATIONAHA.110.009282","article-title":"Cerebral protection during surgery for acute aortic dissection type A: Results of the German Registry for Acute Aortic Dissection Type A (GERAADA)","volume":"124","author":"Hoffmann","year":"2011","journal-title":"Circulation"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1093\/ejcts\/ezu284","article-title":"Current trends in cannulation and neuroprotection during surgery of the aortic arch in Europe","volume":"47","author":"Czerny","year":"2015","journal-title":"Eur. J. Cardiothorac. Surg."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1016\/j.athoracsur.2014.12.067","article-title":"Moderate versus deep hypothermic circulatory arrest for elective aortic transverse hemiarch reconstruction","volume":"99","author":"Vallabhajosyula","year":"2015","journal-title":"Ann. Thorac. Surg."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.athoracsur.2017.06.072","article-title":"Safety of Moderate Hypothermia With Antegrade Cerebral Perfusion in Total Aortic Arch Replacement","volume":"105","author":"Keeling","year":"2018","journal-title":"Ann. Thorac. Surg."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.jtcvs.2013.03.004","article-title":"Moderate hypothermia during aortic arch surgery is associated with reduced risk of early mortality","volume":"146","author":"Tsai","year":"2013","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_44","first-page":"148","article-title":"A meta-analysis of deep hypothermic circulatory arrest vs moderate hypothermic circulatory arrest with selective antegrade cerebral perfusion","volume":"2","author":"Tian","year":"2013","journal-title":"Ann. Cardiothorac. Surg."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1161\/CIRCULATIONAHA.123.067022","article-title":"Cognitive Effects of Body Temperature During Hypothermic Circulatory Arrest Trial (GOT ICE): A Randomized Clinical Trial Comparing Outcomes After Aortic Arch Surgery","volume":"149","author":"Hughes","year":"2024","journal-title":"Circulation"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1016\/j.athoracsur.2015.06.007","article-title":"Is Total Arch Replacement Associated With Worse Outcomes During Repair of Acute Type A Aortic Dissection?","volume":"100","author":"Rice","year":"2015","journal-title":"Ann. Thorac. Surg."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.jtcvs.2018.07.101","article-title":"Acute aortic dissections with entry tear in the arch: A report from the International Registry of Acute Aortic Dissection","volume":"157","author":"Trimarchi","year":"2019","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1093\/ejcts\/ezx218","article-title":"Single-centre experience with the frozen elephant trunk technique in 251 patients over 15\u2009years","volume":"52","author":"Shrestha","year":"2017","journal-title":"Eur. J. Cardiothorac. Surg."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"S175","DOI":"10.1161\/CIRCULATIONAHA.112.000327","article-title":"Stroke and outcomes in patients with acute type A aortic dissection","volume":"128","author":"Bossone","year":"2013","journal-title":"Circulation"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1016\/j.jtcvs.2019.11.003","article-title":"Surgery for type A aortic dissection in patients with cerebral malperfusion: Results from the International Registry of Acute Aortic Dissection","volume":"161","author":"Sultan","year":"2021","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1093\/ejcts\/ezab189","article-title":"Comparative outcomes of total arch versus hemiarch repair in acute DeBakey type I aortic dissection: The impact of 21 years of experience","volume":"60","author":"Ok","year":"2021","journal-title":"Eur. J. Cardiothorac. Surg."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"101457","DOI":"10.1016\/j.jvscit.2024.101457","article-title":"Randomized controlled trials in emergency settings: Taking a HEADSTART on acute type A aortic dissection trials","volume":"10","author":"Vervoort","year":"2024","journal-title":"J. Vasc. Surg. Cases Innov. Tech."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.jtcvs.2011.01.020","article-title":"Branch-first aortic arch replacement with no circulatory arrest or deep hypothermia","volume":"142","author":"Matalanis","year":"2011","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1016\/j.jtcvs.2023.08.012","article-title":"Branch-first aortic arch replacement strategy decreases perioperative mortality","volume":"167","author":"Abt","year":"2024","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1016\/j.jtcvs.2018.09.120","article-title":"Dissected Aorta Repair Through Stent Implantation trial: Canadian results","volume":"157","author":"Bozso","year":"2019","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"ezac581","DOI":"10.1093\/ejcts\/ezac581","article-title":"Treatment of acute type A aortic dissection with the Ascyrus Medical Dissection Stent in a consecutive series of 57 cases","volume":"63","author":"Luehr","year":"2023","journal-title":"Eur. J. Cardiothorac. Surg."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.xjtc.2022.10.011","article-title":"Total arch replacement with extended branched stented anastomosis frozen elephant trunk repair for type A dissection improves operative outcome","volume":"17","author":"Hashizume","year":"2022","journal-title":"JTCVS Tech."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1177\/15266028221095018","article-title":"ARISE: First-In-Human Evaluation of a Novel Stent Graft to Treat Ascending Aortic Dissection","volume":"30","author":"Mariscalco","year":"2023","journal-title":"J. Endovasc. Ther."},{"key":"ref_59","doi-asserted-by":"crossref","unstructured":"Chivasso, P.M.G., Bruno, V.D., Miele, M., Colombino, M., Triggiani, D., Cafarelli, F., Leone, R., Rosapepe, F., De Martino, M., and Morena, E. (2022). Systematic total arch replacement with thoraflex hybrid graft in acute type A aortic dissection: A single centre experience. Front. Cardiovasc. Med., 14.","DOI":"10.3389\/fcvm.2022.997961"},{"key":"ref_60","doi-asserted-by":"crossref","unstructured":"Tan, S.Z.C.P.J.M., Mohammed, I., and Bashir, M. (2022). What Is the Long-Term Clinical Efficacy of the Thoraflex\u2122 Hybrid Prosthesis for Aortic Arch Repair?. Front. Cardiovasc. Med., 9.","DOI":"10.3389\/fcvm.2022.842165"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1055\/s-0042-1756667","article-title":"Frozen Elephant Trunk Sizing: A 30,000-Feet Perspective with Thoraflex Hybrid Stent Graft","volume":"10","author":"Tan","year":"2022","journal-title":"Aorta"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.jvs.2021.03.029","article-title":"Multicenter global early feasibility study to evaluate total endovascular arch repair using three-vessel inner branch stent-grafts for aneurysms and dissections","volume":"74","author":"Tenorio","year":"2021","journal-title":"J. Vasc. Surg."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1177\/1526602820985270","article-title":"Emergent Triple-Branched TEVAR and Redistribution of the Branches to the Supra-Aortic Target Vessels for Treatment of a Contained Ruptured Descending Aortic Aneurysm Associated With a Chronic Type A Aortic Dissection","volume":"28","author":"Stana","year":"2021","journal-title":"J. Endovasc. Ther."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1177\/1526602819852083","article-title":"Endovascular Repair of Ascending Aortic Pathologies With Tubular Endografts: A Single-Center Experience","volume":"26","author":"Tsilimparis","year":"2019","journal-title":"J. Endovasc. Ther."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1016\/j.athoracsur.2018.09.020","article-title":"Emergency Use of Branched Thoracic Endovascular Repair in the Treatment of Aortic Arch Pathologies","volume":"107","author":"Law","year":"2019","journal-title":"Ann. Thorac. Surg."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.jvs.2018.11.046","article-title":"iTalian RegIstry of doUble inner branch stent graft for arch PatHology (the TRIUmPH Registry)","volume":"70","author":"Ferrer","year":"2019","journal-title":"J. Vasc. Surg."},{"key":"ref_67","doi-asserted-by":"crossref","unstructured":"D\u2019onofrio, A., Caraffa, R., Cibin, G., Antonello, M., and Gerosa, G. (2022). Total Endovascular Aortic Arch Repair: From Dream to Reality. Medicina, 58.","DOI":"10.3390\/medicina58030372"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.jaccas.2019.11.071","article-title":"First-in-Human Endo-Bentall Procedure for Simultaneous Treatment of the Ascending Aorta and Aortic Valve","volume":"2","author":"Gaia","year":"2020","journal-title":"JACC Case Rep."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.ejvs.2024.04.008","article-title":"Physician Modified Fenestrated Endografts for Endovascular Aortic Arch Repair in Zone 0","volume":"68","author":"Wen","year":"2024","journal-title":"Eur. J. Vasc. Endovasc. Surg."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/24\/7794\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:56:17Z","timestamp":1760115377000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/24\/7794"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,20]]},"references-count":69,"journal-issue":{"issue":"24","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["jcm13247794"],"URL":"https:\/\/doi.org\/10.3390\/jcm13247794","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,20]]}}}