{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:41:48Z","timestamp":1760146908379,"version":"build-2065373602"},"reference-count":31,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T00:00:00Z","timestamp":1735603200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Objectives: Malnutrition is a common health problem affecting overall body functions, growth, and development. The aim of the present study was to explore any potential changes in solid organ sizes due to malnutrition and, if so, their correlation with the degree of malnutrition. Materials and Methods: Solid organ sizes (liver, spleen, and kidneys) in patients with primary malnutrition were measured prospectively using ultrasonography. Results: A correlation was observed between changes in liver, spleen, and kidney sizes and left kidney parenchymal thickness and the degree of malnutrition in patients. Conclusions: The presence and degree of malnutrition were directly proportional to significant decreases in organ sizes. The present study is the first to reveal a positive correlation between anthropometric measurement Z scores and organ sizes.<\/jats:p>","DOI":"10.3390\/jcm14010169","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T07:34:19Z","timestamp":1735630459000},"page":"169","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ultrasonographic Evaluation of Solid Organ Sizes in Children with Primary Malnutrition: A Preliminary Study"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8558-6295","authenticated-orcid":false,"given":"Kamil","family":"Do\u011fan","sequence":"first","affiliation":[{"name":"Radiology Department, Faculty of Medicine, Kahramanmaras Sutcu Imam University, 46050 Kahramanmaras, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u015e\u00fckr\u00fc","family":"G\u00fcng\u00f6r","sequence":"additional","affiliation":[{"name":"Pediatric Department, Faculty of Medicine, Kahramanmaras Sutcu Imam University, 46050 Kahramanmaras, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adil","family":"Do\u011fan","sequence":"additional","affiliation":[{"name":"Radiology Department, Faculty of Medicine, Kahramanmaras Sutcu Imam University, 46050 Kahramanmaras, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seda Nida","family":"Karak\u00fc\u00e7\u00fck","sequence":"additional","affiliation":[{"name":"Radiology Department, Faculty of Medicine, Kahramanmaras Sutcu Imam University, 46050 Kahramanmaras, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3347","DOI":"10.1007\/s00431-023-05024-x","article-title":"Diaphragm thickness by ultrasound in pediatric patients with primary malnutrition","volume":"182","year":"2023","journal-title":"Eur. J. Pediatr."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"111565","DOI":"10.1016\/j.nut.2021.111565","article-title":"Determinants of malnutrition among children: A systematic review","volume":"96","author":"Raj","year":"2022","journal-title":"Nutrition"},{"key":"ref_3","first-page":"139","article-title":"Pediatric Nutrition in Practice","volume":"Volume 113","author":"Koletzko","year":"2015","journal-title":"World Review Nutrition Dietetics"},{"doi-asserted-by":"crossref","unstructured":"Valeria, D., Cucinotta, U., and Romano, C. (2020). Acute malnutrition in children: Pathophysiology, clinical effects and treatment. Nutrients, 12.","key":"ref_4","DOI":"10.3390\/nu12082413"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"84","DOI":"10.3844\/ajidsp.2005.84.86","article-title":"Prevalence, types and risk factors for malnutrition in displaced Sudanese children","volume":"1","author":"Mamoun","year":"2005","journal-title":"Am. J. Infect. Dis."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.pcl.2009.07.001","article-title":"Protein energy malnutrition","volume":"56","author":"Grover","year":"2009","journal-title":"Pediatr. Clin. N. Am."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12887-020-02094-w","article-title":"Mortality among children under five years admitted for routine care of severe acute malnutrition: A prospective cohort study from Kampala, Uganda","volume":"20","author":"Nalwanga","year":"2020","journal-title":"BMC Pediatr."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1038\/s41390-020-1057-5","article-title":"Thymus size in children with moderate malnutrition: A cohort study from Burkina Faso","volume":"89","author":"Rytter","year":"2021","journal-title":"Pediatr. Res."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1111\/j.1440-1754.2010.01714.x","article-title":"Renal length nomogram in Hong Kong Asian children: Sonographic measurement and multivariable approach","volume":"46","author":"Luk","year":"2010","journal-title":"J. Paediatr. Child Health"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1007\/s00247-019-04486-2","article-title":"Normal sonographic renal length measurements in an Australian pediatric population","volume":"49","author":"Coombs","year":"2019","journal-title":"Pediatr. Radiol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1177\/0884533616671861","article-title":"Diagnosing Pediatric Malnutrition","volume":"32","author":"Bouma","year":"2017","journal-title":"Nutr. Clin. Pract."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1177\/0148607113479972","article-title":"Defining pediatric malnutrition: A paradigm shift toward etiology-related definitions","volume":"37","author":"Mehta","year":"2013","journal-title":"J. Parenter. Enter. Nutr."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/nrdp.2017.67","article-title":"Severe childhood malnutrition","volume":"3","author":"Bhutta","year":"2017","journal-title":"Nat. Rev. Dis. Primers"},{"doi-asserted-by":"crossref","unstructured":"Wu, W.-T., Chang, K.-V., Hsu, Y.-C., Hsu, P.-C., Ricci, V., and \u00d6z\u00e7akar, L. (2020). Artifacts in musculoskeletal ultrasonography: From physics to clinics. Diagnostics, 10.","key":"ref_14","DOI":"10.3390\/diagnostics10090645"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"62","DOI":"10.4329\/wjr.v6.i4.62","article-title":"Liver volumetry: Is imaging reliable? Personal experience and review of the literature","volume":"6","author":"Demozzi","year":"2014","journal-title":"World J. Radiol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1002\/j.2205-0140.2014.tb00026.x","article-title":"Ultrasound measurements of the liver: An intra and inter-rater reliability study","volume":"17","author":"Childs","year":"2014","journal-title":"Australas. J. Ultrasound Med."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"e125","DOI":"10.1016\/j.radi.2015.12.009","article-title":"The development of a practical and uncomplicated predictive equation to determine liver volume from simple linear ultrasound measurements of the liver","volume":"22","author":"Childs","year":"2016","journal-title":"Radiography"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.7863\/jum.2005.24.10.1359","article-title":"Sonographic assessment of the normal limits and percentile curves of liver, spleen, and kidney dimensions in healthy school-aged children","volume":"24","author":"Safak","year":"2005","journal-title":"J. Ultrasound Med."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"143","DOI":"10.5144\/0256-4947.2019.143","article-title":"Sonographic measurements for kidney length in normal Saudi children: Correlation with other body parameters","volume":"39","author":"Mohtasib","year":"2019","journal-title":"Ann. Saudi Med."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1096\/fasebj.30.1_supplement.915.23","article-title":"Study of hematopoiesis in protein restriction: Characterization of bone marrow stromal cells","volume":"30","author":"Santos","year":"2016","journal-title":"FASEB J."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"711","DOI":"10.14202\/vetworld.2017.711-715","article-title":"Honey can repairing damage of liver tissue due to protein energy malnutrition through induction of endogenous stem cells","volume":"10","author":"Prasetyo","year":"2017","journal-title":"Vet. World"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1111\/j.1365-2249.2008.03796.x","article-title":"Malnutrition alters the rates of apoptosis in splenocytes and thymocyte subpopulations of rats","volume":"155","author":"Ortiz","year":"2009","journal-title":"Clin. Exp. Immunol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1007\/s10753-014-9947-5","article-title":"Protein malnutrition alters spleen cell proliferation and IL-2 and IL-10 production by affecting the STAT-1 and STAT-3 balance","volume":"37","author":"Mello","year":"2014","journal-title":"Inflammation"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1159\/000441957","article-title":"Left renal cortical thickness measured by ultrasound can predict early progression of chronic kidney disease","volume":"132","author":"Takata","year":"2016","journal-title":"Nephron"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.jpeds.2016.04.013","article-title":"Both Exocrine Pancreatic Insufficiency and Signs of Pancreatic Inflammation Are Prevalent in Children with Complicated Severe Acute Malnutrition: An Observational Study","volume":"174","author":"Bartels","year":"2016","journal-title":"J. Pediatr."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.nut.2008.11.026","article-title":"Hospital-acquired malnutrition in children with mild clinical conditions","volume":"25","author":"Campanozzi","year":"2009","journal-title":"Nutrition"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/jum.15114","article-title":"Liver, spleen, and kidney size in children as measured by ultrasound: A systematic review","volume":"39","author":"Back","year":"2020","journal-title":"J. Ultrasound Med."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00247-022-05341-7","article-title":"Relationship between ultrasound-measured spleen, liver and anthropometry of children living in a rural community in southwest Nigeria: A cross-sectional study","volume":"52","author":"Fatunla","year":"2022","journal-title":"Pediatr. Radiol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"235","DOI":"10.3109\/07853890.2010.515603","article-title":"New Finnish growth references for children and adolescents aged 0 to 20 years: Length\/height-for-age, weight-for-length\/height, and body mass index-for-age","volume":"43","author":"Saari","year":"2011","journal-title":"Ann. Med."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1007\/s00520-019-04980-1","article-title":"Evaluation of an automated pediatric malnutrition screen using anthropometric measurements in the electronic health record: A quality improvement initiative","volume":"28","author":"Phillips","year":"2020","journal-title":"Support. Care Cancer"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"3359","DOI":"10.1007\/s00261-015-0540-7","article-title":"MRI: First-line imaging modality for pregnant patients with suspected appendicitis","volume":"40","author":"Konrad","year":"2015","journal-title":"Abdom. 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