{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:36:53Z","timestamp":1759970213041,"version":"build-2065373602"},"reference-count":21,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T00:00:00Z","timestamp":1736294400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Siberian Branch of the Russian Academy of Sciences","award":["0419-2022-0002"],"award-info":[{"award-number":["0419-2022-0002"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background and Objectives: We aim to evaluate the dynamics of glycemic status and markers of carbohydrate metabolism 12 months after coronary artery bypass grafting (CABG) and their relationship with the one-year prognosis. Materials and Methods: The analysis of outcomes of 653 patients during 1 year after coronary artery bypass grafting is presented. In those patients who visited the study center after 1 year, markers of carbohydrate metabolism (glucose, glycated hemoglobin, fructosamine, 1.5 anhydroglucitol) were assessed; in 371 of them, they were studied at three points\u2014before surgery, before discharge from the hospital, and one year after surgery. The influence of these indicators on the incidence of cardiovascular events (death from any cause, myocardial infarction, stroke, repeat myocardial revascularization, surgical interventions on non-coronary arteries, amputations due to peripheral atherosclerosis, emergency hospitalizations due to cardiovascular disease, or combined endpoint [CEP]) was assessed during the year after CABG. Groups with (n = 59)\/absence (n = 594) of the combined endpoint were formed and compared based on the dynamics of carbohydrate metabolism markers over the course of a year. Additionally, factors associated with the development of major adverse cardiovascular events (MACE) after CABG were assessed. Results: After 1 year, the number of patients with type 2 diabetes increased from 23.9% to 25.6% and prediabetes from 17.2% to 26.6% (p &lt; 0.001). Among patients with diabetes mellitus, the following dynamics of carbohydrate metabolism markers were noted: a decrease in glucose levels in both groups (with or without CEP), glycated hemoglobin in the group without CEP, and fructosamine in the group with CEP. There were no differences in the intergroup comparison of all the described markers (glucose, fructosamine, glycated hemoglobin) and carbohydrate metabolism at all points. The following factors were associated with the development of MACE within a year after CABG: the presence of peripheral arterial disease, preoperative fibrinogen level, the risk of surgery according to the EuroSCORE scale, and off-pump CABG. Conclusions: In patients with diabetes mellitus one year after coronary artery bypass grafting, a decrease in glucose and glycated hemoglobin levels was noted. No differences in the dynamics of carbohydrate metabolism markers were found in the groups of patients with and without cardiovascular complications. The impact of glycated hemoglobin dynamics one year after CABG on long-term prognosis requires further research.<\/jats:p>","DOI":"10.3390\/jcm14020351","type":"journal-article","created":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T11:56:22Z","timestamp":1736337382000},"page":"351","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dynamics of Glycemic Status and Glucose Metabolism Markers 12 Months After Coronary Artery Bypass Grafting and Their Relationship with the Annual Prognosis of Patients"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0963-4793","authenticated-orcid":false,"given":"Alexey N.","family":"Sumin","sequence":"first","affiliation":[{"name":"Federal State Budgetary Scientific Institution, Research Institute for Complex Issues of Cardiovascular Diseases, Academician LS Barbarash Boulevard, 6, Kemerovo 650002, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9396-4575","authenticated-orcid":false,"given":"Natalia A.","family":"Bezdenezhnykh","sequence":"additional","affiliation":[{"name":"Federal State Budgetary Scientific Institution, Research Institute for Complex Issues of Cardiovascular Diseases, Academician LS Barbarash Boulevard, 6, Kemerovo 650002, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3996-3325","authenticated-orcid":false,"given":"Ekaterina V.","family":"Belik","sequence":"additional","affiliation":[{"name":"Federal State Budgetary Scientific Institution, Research Institute for Complex Issues of Cardiovascular Diseases, Academician LS Barbarash Boulevard, 6, Kemerovo 650002, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6890-3287","authenticated-orcid":false,"given":"Yulia A.","family":"Dyleva","sequence":"additional","affiliation":[{"name":"Federal State Budgetary Scientific Institution, Research Institute for Complex Issues of Cardiovascular Diseases, Academician LS Barbarash Boulevard, 6, Kemerovo 650002, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4420-4350","authenticated-orcid":false,"given":"Andrey V.","family":"Bezdenezhnykh","sequence":"additional","affiliation":[{"name":"Limited Liability Company, Family Health and Reproduction Center Krasnaya Gorka, Suvorova st., 3A, Kemerovo 650044, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga V.","family":"Gruzdeva","sequence":"additional","affiliation":[{"name":"Federal State Budgetary Scientific Institution, Research Institute for Complex Issues of Cardiovascular Diseases, Academician LS Barbarash Boulevard, 6, Kemerovo 650002, Russia"},{"name":"Federal State Budgetary Educational Institution of Higher Education, Kemerovo State Medical University, Voroshilova st., 22A, Kemerovo 650056, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4642-3610","authenticated-orcid":false,"given":"Olga L.","family":"Barbarash","sequence":"additional","affiliation":[{"name":"Federal State Budgetary Scientific Institution, Research Institute for Complex Issues of Cardiovascular Diseases, Academician LS Barbarash Boulevard, 6, Kemerovo 650002, Russia"},{"name":"Federal State Budgetary Educational Institution of Higher Education, Kemerovo State Medical University, Voroshilova st., 22A, Kemerovo 650056, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1093\/eurheartj\/ehy394","article-title":"2018 ESC\/EACTS Guidelines on myocardial revascularization","volume":"40","author":"Neumann","year":"2019","journal-title":"Eur. 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