{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T14:40:18Z","timestamp":1792507218977,"version":"4.5.0"},"reference-count":36,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T00:00:00Z","timestamp":1737072000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: After open-wedge high tibial osteotomy (OWHTO), the patella is displaced distally, causing patellofemoral joint degeneration. The objective of this study was to ascertain whether the combination of OWHTO and lateral retinacular release (LRR) can prevent articular cartilage degeneration of the patellofemoral joint using magnetic resonance imaging T2 mapping. Methods: This study included 37 patients (37 knees) who underwent OWHTO alone (OWHTO group) and 37 patients (37 knees) who underwent OWHTO with LRR (OWHTO + LRR group) with a correction angle of &lt;10\u00b0 for varus knee osteoarthritis. MRI was performed on all knees prior to and 6 months after surgery to assess the patellar cartilage in sagittal images for T2 mapping. Three regions of interest, (the medial facet, patellar ridge, and lateral facet), were established for the articular cartilage on the patellar side. The T2 values were subsequently quantified. Lower limb alignment, patellar height, patellar tilt angle, and lateral shift ratio were evaluated pre-and post-surgery. Results: Mean T2 values at 6 months post-surgery of the medial facet and patellar ridge of the OWHTO group showed a significant increase after surgery; no significant changes were observed in either region in the OWHTO + LRR group. In both groups, a significant decrease in patellar tilt angle was observed postoperatively; no change was noted in the lateral shift ratio or congruence angle. The change in patellar tilt angle was significantly lower in the OWHTO + LRR group than in the OWHTO group. Conclusions: LRR combined with OWHTO prevented patellofemoral joint cartilage degeneration after surgery in cases of varus knee osteoarthritis.<\/jats:p>","DOI":"10.3390\/jcm14020595","type":"journal-article","created":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T11:24:56Z","timestamp":1737113096000},"page":"595","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effect of Open-Wedge High Tibial Osteotomy and Lateral Retinacular Release on the Articular Cartilage of the Patellofemoral Joint: Analysis Using Magnetic Resonance Imaging T2 Mapping"],"prefix":"10.3390","volume":"14","author":[{"given":"Shuji","family":"Nakagawa","sequence":"first","affiliation":[{"name":"Department of Sports and Para-Sports Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Kan","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Kyoto Interdisciplinary Institute of Community Medicine, Mibu-Higashitakadacho, Nakagyo-ku, Kyoto 604-8845, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0784-7426","authenticated-orcid":false,"given":"Yuji","family":"Arai","sequence":"additional","affiliation":[{"name":"Department of Sports and Para-Sports Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shintaro","family":"Komaki","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manabu","family":"Hino","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Kyoto Interdisciplinary Institute of Community Medicine, Mibu-Higashitakadacho, Nakagyo-ku, Kyoto 604-8845, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsuo","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Krakowski, P., Rejniak, A., Sobczyk, J., and Karpi\u0144ski, R. (2024). Cartilage integrity: A review of mechanical and frictional properties and repair approaches in osteoarthritis. Healthcare, 12.","DOI":"10.3390\/healthcare12161648"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.arthro.2019.08.040","article-title":"Survival and risk factor analysis of medial open wedge high tibial osteotomy for unicompartment knee osteoarthritis","volume":"36","author":"Jin","year":"2020","journal-title":"Arthroscopy"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1007\/s00167-018-5334-3","article-title":"Large opening gaps, unstable hinge fractures, and osteotomy line below the safe zone cause delayed bone healing after open-wedge high tibial osteotomy","volume":"27","author":"Goshima","year":"2019","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.arthro.2016.09.034","article-title":"Medial open-wedge high tibial osteotomy may adversely affect the patellofemoral joint","volume":"33","author":"Kim","year":"2017","journal-title":"Arthroscopy"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"e14299","DOI":"10.1097\/MD.0000000000014299","article-title":"Large deformity correction in medial open-wedge high tibial osteotomy may cause degeneration of patellofemoral cartilage: A retrospective study","volume":"98","author":"Otakara","year":"2019","journal-title":"Medicine"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1007\/s00167-018-5128-7","article-title":"Deterioration of patellofemoral cartilage status after medial open-wedge high tibial osteotomy","volume":"27","author":"Tanaka","year":"2019","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"10225536221151132","DOI":"10.1177\/10225536221151132","article-title":"Cartilage degeneration of patellofemoral joint occurs in open wedge high tibial osteotomy, rather than in hybrid closed wedge high tibial osteotomy, during the early postoperative period: A qualitative analysis using MRI T(2) mapping","volume":"31","author":"Komaki","year":"2023","journal-title":"J. Orthop. Surg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1007\/s00167-002-0334-7","article-title":"Improvements in surgical technique of valgus high tibial osteotomy","volume":"11","author":"Lobenhoffer","year":"2003","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_9","first-page":"1","article-title":"Debridement synovectomy, and lateral release","volume":"382","author":"Farr","year":"2004","journal-title":"AAOS Course Lect."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1177\/036354659001800405","article-title":"Lateral release of the patella: Indications and contraindications","volume":"18","author":"Kolowich","year":"1990","journal-title":"Am. J. Sports. Med."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1016\/j.mri.2015.08.002","article-title":"Early postoperative cartilage evaluation by magnetic resonance imaging using T2 mapping after arthroscopic partial medial meniscectomy","volume":"33","author":"Kato","year":"2015","journal-title":"Magn. Reason. Imaging"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"633","DOI":"10.3109\/17453678208992270","article-title":"Use of a guide instrument for compartmental knee arthroplasty","volume":"53","author":"Lindstrand","year":"1982","journal-title":"Acta Orthop. Scand."},{"key":"ref_13","first-page":"48","article-title":"Mechanical axis deviation of the lower limbs. Preoperative planning of uniapical angular deformities of the tibia or femur","volume":"280","author":"Paley","year":"1992","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_14","first-page":"317","article-title":"Patella infera. Apropos of 128 cases","volume":"68","author":"Caton","year":"1982","journal-title":"Rev. Chir. Orthop. R\u00e9paratrice Appar. Mot."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.2106\/00004623-197456070-00007","article-title":"Roentgeno- graphic analysis of patella-femoral congruence","volume":"56","author":"Merchant","year":"1974","journal-title":"J. Bone J. Surg."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1148\/101.1.101","article-title":"Patella position in the normal knee joint","volume":"101","author":"Insall","year":"1971","journal-title":"Radiology"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1302\/0301-620X.59B2.873986","article-title":"A new method of measuring patellar height","volume":"59","author":"Blackburne","year":"1977","journal-title":"J. Bone J. Surg. Br."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1136\/ard.16.4.494","article-title":"Radiological assessment of osteo-arthrosis","volume":"16","author":"Kellgren","year":"1957","journal-title":"Ann. Rheum. Dis."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Ogata, H., Mori, M., Jingushi, Y., Matsuzaki, H., Katahira, K., Ishimatsu, A., Enokizu-Ogawa, A., Taguchi, K., Moriwaki, A., and Yoshida, M. (2021). Impact of visceral fat on the prognosis of coronavirus disease 2019: An observational cohort study. BMC Infect. Dis., 21.","DOI":"10.1186\/s12879-021-06958-z"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"45","DOI":"10.2106\/00004623-200300002-00007","article-title":"Histological assessment of cartilage repair: A report by the Histology Endpoint Committee of the International Cartilage Repair Society (ICRS)","volume":"85","author":"Aigner","year":"2003","journal-title":"J. Bone J. Surg. Am."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.rbo.2016.06.006","article-title":"Lateral patellar retinacular release: Changes over the last ten years","volume":"52","author":"Fonseca","year":"2017","journal-title":"Rev. Bras. Ortop."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1055\/s-2004-861764","article-title":"Cartilage MRI T2 relaxation time mapping: Overview and applications","volume":"8","author":"Mosher","year":"2004","journal-title":"Semin. Musculoskelet Radiol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"e549","DOI":"10.5114\/pjr.2019.91375","article-title":"T1 and T2 mapping of articular cartilage and menisci in early osteoarthritis of the knee using 3-Tesla magnetic resonance imaging","volume":"84","author":"Mittal","year":"2019","journal-title":"Pol. J. Radiol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.arthro.2023.05.007","article-title":"Patellofemoral osteoarthritis progression after open-wedge high tibial osteotomy does not affect the clinical outcomes or survivorship at minimum 7 years\u2019 Follow-Up","volume":"40","author":"Goshima","year":"2024","journal-title":"Arthroscopy"},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Migliorini, F., L\u00fcring, C., Eschweiler, J., Baroncini, A., Driessen, A., Spiezia, F., Tingart, M., and Maffulli, N. (2021). Isolated arthroscopic lateral retinacular release for lateral patellar compression syndrome. Life, 11.","DOI":"10.3390\/life11040295"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1053\/jars.2002.32306","article-title":"Lateral release for patellofemoral arthritis","volume":"18","author":"Aderinto","year":"2002","journal-title":"Arthroscopy"},{"key":"ref_27","first-page":"34","article-title":"Patellofemoral instability: Surgical treatment of soft tissues","volume":"1","author":"Panni","year":"2013","journal-title":"Joints"},{"key":"ref_28","first-page":"1","article-title":"What is the role of lateral retinacular release?","volume":"92","author":"Clifton","year":"2010","journal-title":"J. Bone J. Surg. Br."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1007\/s00167-006-0261-0","article-title":"Dynamic measurement of patellofemoral kinematics and contact pressure after lateral retinacular release: An in vitro study","volume":"15","author":"Ostermeier","year":"2007","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0968-0160(01)00147-8","article-title":"High tibial osteotomy with anterior advancement of distal fragment for medial and patellofemoral compartmental osteoarthritis of the knee","volume":"9","author":"Saito","year":"2002","journal-title":"Knee"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1097\/01.blo.0000180603.08110.1f","article-title":"Improvement of proximal tibial osteotomy results by lateral retinacular release","volume":"441","author":"Christodoulou","year":"2005","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"2860","DOI":"10.21037\/qims-22-926","article-title":"Effect of open-wedge high tibial osteotomy and lateral patellofemoral retinacular release on patellar position: An X-ray imaging-based comparative study","volume":"13","author":"Li","year":"2023","journal-title":"Quant. Imaging Med. Surg."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1007\/s00167-007-0305-0","article-title":"The influence of open and closed high tibial osteotomy on dynamic patellar tracking: A biomechanical study","volume":"15","author":"Gaasbeek","year":"2007","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1007\/s00167-010-1077-5","article-title":"Opening wedge high tibial osteotomy affects both the lateral patellar tilt and patellar height","volume":"18","author":"Bito","year":"2010","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s00167-014-3349-y","article-title":"Changes in patellofemoral alignment do not cause clinical impact after open-wedge high tibial osteotomy","volume":"24","author":"Lee","year":"2016","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"241","DOI":"10.5792\/ksrr.18.006","article-title":"The effect of concomitant arthroscopic lateral retinacular release on postoperative patellar position and orientation in open wedge high tibial osteotomy","volume":"30","author":"Murayama","year":"2018","journal-title":"Knee Surg. Relat. Res."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/2\/595\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T10:31:07Z","timestamp":1759919467000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/2\/595"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,17]]},"references-count":36,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,1]]}},"alternative-id":["jcm14020595"],"URL":"https:\/\/doi.org\/10.3390\/jcm14020595","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,17]]}}}