{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T01:44:43Z","timestamp":1774575883565,"version":"3.50.1"},"reference-count":37,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T00:00:00Z","timestamp":1737417600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Age is a relevant risk factor for the development of atrial arrhythmias and an independent predictor of adverse cardiovascular outcomes. The incidence of atrial tachycardia (AT) is known to increase with aging, but so far, there are no data on elderly patients with AT. Therefore, we sought to assess the safety and outcomes of AT ablation in patients \u226575 years compared to those &lt;75 years. Methods: A total of 420 consecutive patients undergoing AT ablation after previous cardiac interventions (mean 2.1 \u00b1 0.1 prior ablation procedures) were analyzed. Safety, as well as acute and mid-term outcomes of AT ablation were compared between 140 patients \u226575 years (mean age 78.1 \u00b1 0.2 years, 22.9% aged \u226580 years (range 80\u201386 years)) and 280 patients &lt;75 years (mean age 62.2 \u00b1 0.6 years). Results: Patients \u226575 years were more often female (54.3% vs. 38.2%; p = 0.0024) and presented with more cardiac comorbidities, including arterial hypertension (85.0% vs. 64.3%; p &lt; 0.0001) and coronary artery disease (33.6% vs. 18.2%; p = 0.0006). Acute success of AT ablation was reached in 96.4% vs. 97.9% of patients (p = 0.5173). Major complications (1.4% vs. 0.7%; p = 0.6035) and duration of hospital stay (2 (IQR 2\u20134) days vs. 2 (IQR 2\u20133) days; p = 0.9125) did not differ significantly between groups. During a follow-up of 364 (IQR 183\u2013729.5) days, arrhythmia recurrences occurred in 45.0% vs. 49.3% (p = 0.4684), whereas repeat ablation was less frequently performed in patients \u226575 years (25.7% vs. 36.1%; p = 0.0361). Conclusions: AT ablation in patients \u226575 years after previous cardiac interventions in tertiary arrhythmia centers is safe and effective. Therefore, AT ablation should not be ruled out in elderly patients due to age alone, but should be considered based on arrhythmia burden, symptom severity and concomitant clinical and procedural risk factors.<\/jats:p>","DOI":"10.3390\/jcm14030675","type":"journal-article","created":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T08:46:26Z","timestamp":1737449186000},"page":"675","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Safety and Outcomes of Catheter Ablation for Consecutive Atrial Tachycardia in Elderly Patients After Previous Cardiac Interventions"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9163-6693","authenticated-orcid":false,"given":"Ann-Kathrin","family":"Kahle","sequence":"first","affiliation":[{"name":"Division of Cardiology, Angiology, Intensive Care Medicine, EVK D\u00fcsseldorf, cNEP, cardiac Neuro- and Electrophysiology Research Consortium, Kirchfeldstrasse 40, 40217 D\u00fcsseldorf, Germany"},{"name":"Department of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, University Hospital D\u00fcsseldorf, Moorenstrasse 5, 40225 D\u00fcsseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5260-6352","authenticated-orcid":false,"given":"Fares-Alexander","family":"Alken","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Angiology, Intensive Care Medicine, EVK D\u00fcsseldorf, cNEP, cardiac Neuro- and Electrophysiology Research Consortium, Kirchfeldstrasse 40, 40217 D\u00fcsseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3237-140X","authenticated-orcid":false,"given":"Katharina","family":"Scherschel","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Angiology, Intensive Care Medicine, EVK D\u00fcsseldorf, cNEP, cardiac Neuro- and Electrophysiology Research Consortium, Kirchfeldstrasse 40, 40217 D\u00fcsseldorf, Germany"},{"name":"Institute of Neural and Sensory Physiology, cNEP, cardiac Neuro- and Electrophysiology Research Consortium, Medical Faculty, Heinrich Heine University D\u00fcsseldorf, Universit\u00e4tsstrasse 1, 40225 D\u00fcsseldorf, Germany"},{"name":"Cardiovascular Research Institute D\u00fcsseldorf (CARID), Medical Faculty and University Hospital D\u00fcsseldorf, Heinrich Heine University, Moorenstrasse 5, 40225 D\u00fcsseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ernan","family":"Zhu","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Angiology, Intensive Care Medicine, EVK D\u00fcsseldorf, cNEP, cardiac Neuro- and Electrophysiology Research Consortium, Kirchfeldstrasse 40, 40217 D\u00fcsseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie A.","family":"Gunawardene","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Internal Intensive Care Medicine, Asklepios Hospital St. Georg, Lohm\u00fchlenstrasse 5, 20099 Hamburg, Germany"},{"name":"Faculty of Medicine, Semmelweis University, 1085 Budapest, Hungary"},{"name":"German Center for Cardiovascular Research (DZHK), Partner Site Hamburg\/Kiel\/L\u00fcbeck, 20251 Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Metzner","sequence":"additional","affiliation":[{"name":"German Center for Cardiovascular Research (DZHK), Partner Site Hamburg\/Kiel\/L\u00fcbeck, 20251 Hamburg, Germany"},{"name":"Department of Cardiology, University Heart and Vascular Center Hamburg, University Hospital Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Willems","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Internal Intensive Care Medicine, Asklepios Hospital St. Georg, Lohm\u00fchlenstrasse 5, 20099 Hamburg, Germany"},{"name":"Faculty of Medicine, Semmelweis University, 1085 Budapest, Hungary"},{"name":"German Center for Cardiovascular Research (DZHK), Partner Site Hamburg\/Kiel\/L\u00fcbeck, 20251 Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0217-3960","authenticated-orcid":false,"given":"Christian","family":"Meyer","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Angiology, Intensive Care Medicine, EVK D\u00fcsseldorf, cNEP, cardiac Neuro- and Electrophysiology Research Consortium, Kirchfeldstrasse 40, 40217 D\u00fcsseldorf, Germany"},{"name":"Institute of Neural and Sensory Physiology, cNEP, cardiac Neuro- and Electrophysiology Research Consortium, Medical Faculty, Heinrich Heine University D\u00fcsseldorf, Universit\u00e4tsstrasse 1, 40225 D\u00fcsseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"4127","DOI":"10.1093\/eurheartj\/ehac471","article-title":"Attaining sinus rhythm mediates improved outcome with early rhythm control therapy of atrial fibrillation: The EAST-AFNET 4 trial","volume":"43","author":"Eckardt","year":"2022","journal-title":"Eur. 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