{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T18:42:43Z","timestamp":1776883363663,"version":"3.51.2"},"reference-count":16,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,1,26]],"date-time":"2025-01-26T00:00:00Z","timestamp":1737849600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: The objective was to assess visual performance and the overall satisfaction of extended-depth-of-focus (EDOF) contact lenses (CLs) in a presbyopic population. Methods: We prospectively investigated visual acuity at all distances (0.3, 0.4, 0.5, 0.7, 1, and 5 m), higher-order aberrations (HOAs), contrast sensitivity function, and overall satisfaction score, before and during EDOF CL wear in 42 eyes of 21 presbyopic subjects (1 man and 20 women). Results: Binocular visual acuity at 0.3, 0.5, 0.7, 1, 2, 3, and 5 m when wearing EDOF CLs was 0.01 \u00b1 0.14, \u22120.08 \u00b1 0.02, \u22120.08 \u00b1 0.02, \u22120.08 \u00b1 0.00, \u22120.08 \u00b1 0.00, \u22120.08 \u00b1 0.02, and \u22120.07 \u00b1 0.02, respectively. We found a significant improvement at near to intermediate distances (0.3, and 0.5 m), but no significant change at intermediate to far distances (0.7, 1, 2, 3, and 5 m) between before and during CL wear. The area under the log contrast sensitivity function was not significantly changed under photopic nor mesopic conditions (p = 0.099, and p = 0.689). Ocular third-order aberrations, fourth-order aberrations, or total HOAs for a 4 mm pupil significantly increased. The overall satisfaction score significantly improved by wearing EDOF CLs. Conclusions: EDOF CLs significantly improved visual acuity at near to intermediate distances, while maintaining far vision, and the effect of contrast sensitivity was minimal, suggesting the viability of presbyopic correction in such candidates.<\/jats:p>","DOI":"10.3390\/jcm14030818","type":"journal-article","created":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T07:54:08Z","timestamp":1738050848000},"page":"818","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Visual Performance and Satisfaction of Extended Depth of Focus Contact Lenses in Presbyopic Subjects"],"prefix":"10.3390","volume":"14","author":[{"given":"Kazutaka","family":"Kamiya","sequence":"first","affiliation":[{"name":"Visual Physiology, School of Allied Health Sciences, Kitasato University, Sagamihara 2520373, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shota","family":"Tokuda","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Miyata Eye Hospital, Miyazaki 8850051, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoko","family":"Kaida","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Miyata Eye Hospital, Miyazaki 8850051, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shizuka","family":"Higashi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Miyata Eye Hospital, Miyazaki 8850051, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Midori","family":"Hashiguchi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Miyata Eye Hospital, Miyazaki 8850051, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eriko","family":"Kanaya","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Miyata Eye Hospital, Miyazaki 8850051, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazunori","family":"Miyata","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Miyata Eye Hospital, Miyazaki 8850051, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1001\/archopht.126.12.1731","article-title":"Global vision impairment due to uncorrected presbyopia","volume":"126","author":"Holden","year":"2008","journal-title":"Arch. Ophthalmol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.preteyeres.2018.09.004","article-title":"Presbyopia: Effectiveness of correction strategies","volume":"68","author":"Wolffsohn","year":"2019","journal-title":"Prog. Retin. Eye Res."},{"key":"ref_3","first-page":"319","article-title":"Efficacy of Presbyopia-Correcting Contact Lenses: A Systematic Review","volume":"49","year":"2023","journal-title":"Eye Contact Lens"},{"key":"ref_4","first-page":"28","article-title":"International contact lens prescribing in 2022","volume":"38","author":"Morgan","year":"2023","journal-title":"Contact Lens Spectr."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.clae.2017.12.012","article-title":"Fitting success for three multifocal designs: Multicentre randomised trial","volume":"41","year":"2018","journal-title":"Contact Lens Anterior Eye"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1097\/OPX.0000000000000806","article-title":"Short-Term Visual Performance of Novel Extended Depth-of-Focus Contact Lenses","volume":"93","author":"Tilia","year":"2016","journal-title":"Optom. Vis. Sci."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.optom.2016.04.003","article-title":"Short-term comparison between extended depth-of-focus prototype contact lenses and a commercially-available center-near multifocal","volume":"10","author":"Tilia","year":"2017","journal-title":"J. Optom."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.optom.2017.04.001","article-title":"Extended depth of focus contact lenses vs. two commercial multifocals: Part 2. Visual performance after 1 week of lens wear","volume":"11","author":"Bakaraju","year":"2018","journal-title":"J. Optom."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"S157","DOI":"10.1097\/ICL.0000000000000430","article-title":"Comparison of Extended Depth-of-Focus Prototype Contact Lenses with the 1-Day ACUVUE MOIST MULTIFOCAL After One Week of Wear","volume":"44","author":"Sha","year":"2018","journal-title":"Eye Contact Lens"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"101384","DOI":"10.1016\/j.clae.2020.11.004","article-title":"Visual function, ocular surface integrity and symptomatology of a new extended depth-of-focus and a conventional multifocal contact lens","volume":"44","author":"Crooke","year":"2021","journal-title":"Contact Lens Anterior Eye"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1007\/s10384-021-00862-4","article-title":"Comparison of visual performance between extended depth of focus contact lens and single-vision contact lens in eyes with monofocal intraocular lens","volume":"65","author":"Hiraoka","year":"2021","journal-title":"Jpn. J. Ophthalmol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.optom.2017.04.003","article-title":"Extended depth of focus contact lenses vs. two commercial multifocals: Part 1. Optical performance evaluation via computed through-focus retinal image quality metrics","volume":"11","author":"Bakaraju","year":"2018","journal-title":"J. Optom."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1097\/OPX.0000000000000030","article-title":"Power profiles of multifocal contact lenses and their interpretation","volume":"90","author":"Plainis","year":"2013","journal-title":"Optom. Vis. Sci."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"397","DOI":"10.3928\/1081-597X-19980701-05","article-title":"Corneal aberrations and visual performance after radial keratotomy","volume":"14","author":"Applegate","year":"1998","journal-title":"J. Refract. Surg."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"6817","DOI":"10.1021\/acsnano.3c12072","article-title":"Smart Contact Lenses for Healthcare Monitoring and Therapy","volume":"18","author":"Liu","year":"2024","journal-title":"ACS Nano"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"154823","DOI":"10.1016\/j.cej.2024.154823","article-title":"Smart contact Lenses: From rational design strategies to wearable health monitoring","volume":"497","author":"Han","year":"2024","journal-title":"Chem. Eng. J."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/3\/818\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T10:36:46Z","timestamp":1759919806000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/3\/818"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,26]]},"references-count":16,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,2]]}},"alternative-id":["jcm14030818"],"URL":"https:\/\/doi.org\/10.3390\/jcm14030818","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,26]]}}}