{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T02:22:23Z","timestamp":1790734943622,"version":"4.1.0"},"reference-count":26,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T00:00:00Z","timestamp":1738022400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: An acute aortic dissection (AAD) is a cardiovascular emergency with high mortality rates if left untreated. Survival has increased due to improvements in diagnosis and therapy. However, during their recovery, survivors frequently encounter major social, psychological, and physical challenges. This study aimed to evaluate the recovery experience of AAD survivors in The Netherlands. Insights on sleep quality, physical activity, and quality of life were collected from a unique nationwide cohort of AAD survivors recruited through the national patient support network \u2018Stichting Aorta Dissectie Nederland\u2019. Methods: This study was conducted among AAD survivors who were recruited through a national association for aortic dissection known as \u2018Stichting Aorta Dissectie Nederland (SADN)\u2019. The participants (n = 61) completed questionnaires assessing demographic data, physical activity, sleep quality, and health-related QoL. Results: The cohort had a mean age of 60.1 years, and 47.5% of the participants were female. The prevalence of sleep disruptions was high, as 55.7% of the people were categorized as bad sleepers (PSQI &gt; 5). Poor sleep was associated with low physical activity and a higher BMI. The physical activity levels varied, with 47.5% reporting moderate activity levels and 44.3% reporting high activity levels. The QoL scores varied greatly among the participants, with significant impairment across all fields and reduced enthusiasm for daily activities. Poor sleepers reported significantly lower QoL (p &lt; 0.001). Conclusions: Our study highlights significant gaps in post-AAD care, particularly addressing QoL, sleep, and physical activity. By acknowledging the multifaceted nature of recovery, healthcare providers can develop tailored interventions that empower survivors to achieve better quality of life.<\/jats:p>","DOI":"10.3390\/jcm14030859","type":"journal-article","created":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T08:57:48Z","timestamp":1738054668000},"page":"859","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["From Survival to Recovery: Understanding the Life Impact of an Acute Aortic Dissection Through Activity, Sleep, and Quality of Life"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-6926-9890","authenticated-orcid":false,"given":"Nora","family":"Bacour","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, Amsterdam University Medical Center Location AMC, 1105 AZ Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simran","family":"Grewal","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Onze Lieve Vrouwe Gasthuis, 1091 AC Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rutger T.","family":"Theijsse","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Amsterdam University Medical Center Location AMC, 1105 AZ Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6507-3855","authenticated-orcid":false,"given":"Robert J. M.","family":"Klautz","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Amsterdam University Medical Center Location AMC, 1105 AZ Amsterdam, The Netherlands"},{"name":"Department of Cardiothoracic Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9981-8336","authenticated-orcid":false,"given":"Nimrat","family":"Grewal","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Amsterdam University Medical Center Location AMC, 1105 AZ Amsterdam, The Netherlands"},{"name":"Department of Cardiothoracic Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands"},{"name":"Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e230421186875","DOI":"10.2174\/1573403X16666201014142930","article-title":"Aortic Dissection: A Review of the Pathophysiology, Management and Prospective Advances","volume":"17","author":"Sayed","year":"2021","journal-title":"Curr. Cardiol. Rev."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e33017","DOI":"10.1097\/MD.0000000000033017","article-title":"How to help aortic dissection survivors with recovery?: A health promotion program based on the comprehensive theory of health behavior change and literature review","volume":"102","author":"Lang","year":"2023","journal-title":"Medicine"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1016\/j.hlc.2020.05.113","article-title":"Factors Affecting Outcomes in Acute Type A Aortic Dissection: A Systematic Review","volume":"29","author":"Harky","year":"2020","journal-title":"Heart Lung Circ."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1053\/j.semvascsurg.2022.02.005","article-title":"The mental health impact of aortic dissection","volume":"35","author":"Ilonzo","year":"2022","journal-title":"Semin. Vasc. Surg."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1177\/2047487319878958","article-title":"Systematic review of cardiac rehabilitation guidelines: Quality and scope","volume":"27","author":"Mehra","year":"2020","journal-title":"Eur. J. Prev. Cardiol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"e334","DOI":"10.1161\/CIR.0000000000001106","article-title":"2022 ACC\/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association\/American College of Cardiology Joint Committee on Clinical Practice Guidelines","volume":"146","author":"Isselbacher","year":"2022","journal-title":"Circulation"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"3227","DOI":"10.1093\/eurheartj\/ehab484","article-title":"2021 ESC Guidelines on cardiovascular disease prevention in clinical practice: Developed by the Task Force for cardiovascular disease prevention in clinical practice with representatives of the European Society of Cardiology and 12 medical societies With the special contribution of the European Association of Preventive Cardiology (EAPC)","volume":"42","author":"Visseren","year":"2021","journal-title":"Eur. Heart J."},{"key":"ref_8","first-page":"e45898","article-title":"The Interplay Between Sleep Disorders and Cardiovascular Diseases: A Systematic Review","volume":"15","author":"Ravichandran","year":"2023","journal-title":"Cureus"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"e335","DOI":"10.1055\/s-0044-1785522","article-title":"Can Improving Postoperative Sleep Speed Up Surgical Recovery?","volume":"17","author":"Guerreiro","year":"2024","journal-title":"Sleep Sci."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1177\/2047487320916823","article-title":"Physical inactivity and cardiovascular disease at the time of coronavirus disease 2019 (COVID-19)","volume":"27","author":"Lippi","year":"2020","journal-title":"Eur. J. Prev. Cardiol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1002\/clc.22418","article-title":"Survivors of Aortic Dissection: Activity, Mental Health, and Sexual Function","volume":"38","author":"Chaddha","year":"2015","journal-title":"Clin. Cardiol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s12955-016-0576-6","article-title":"Decreased physical activity is a predictor for a complicated recovery post cardiac surgery","volume":"15","author":"Timman","year":"2017","journal-title":"Health Qual. Life Outcomes"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1161\/CIRCRESAHA.118.312669","article-title":"Sedentary Behavior, Exercise, and Cardiovascular Health","volume":"124","author":"Lavie","year":"2019","journal-title":"Circ. Res."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Sember, V., Meh, K., Soric, M., Starc, G., Rocha, P., and Jurak, G. (2020). Validity and Reliability of International Physical Activity Questionnaires for Adults across EU Countries: Systematic Review and Meta Analysis. Int. J. Environ. Res. Public Health, 17.","DOI":"10.3390\/ijerph17197161"},{"key":"ref_15","unstructured":"Cheng, H.L. (2023, November 01). A Simple, Easy-to-Use Spreadsheet for Automatic Scoring of the International Physical Activity Questionnaire (IPAQ) Short Form. Available online: https:\/\/pdfcoffee.com\/ipaq-sfscoring-pdf-free.html."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0168-8510(90)90421-9","article-title":"EuroQol\u2014A new facility for the measurement of health-related quality of life","volume":"16","author":"EuroQol","year":"1990","journal-title":"Health Policy"},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Huber, M.B., Reitmeir, P., Vogelmann, M., and Leidl, R. (2016). EQ-5D-5L in the General German Population: Comparison and Evaluation of Three Yearly Cross-Section Surveys. Int. J. Environ. Res. Public Health, 13.","DOI":"10.3390\/ijerph13030343"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.jval.2016.01.003","article-title":"Dutch Tariff for the Five-Level Version of EQ-5D","volume":"19","author":"Versteegh","year":"2016","journal-title":"Value Health"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0165-1781(89)90047-4","article-title":"The Pittsburgh Sleep Quality Index: A new instrument for psychiatric practice and research","volume":"28","author":"Buysse","year":"1989","journal-title":"Psychiatry Res."},{"key":"ref_20","unstructured":"Forde, C. (2018). Scoring the international physical activity questionnaire (IPAQ). Univ. Dublin, 3."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.apmr.2023.04.026","article-title":"Use of EQ-5D-5L for Assessing Patient-Reported Outcomes in a National Register for Specialized Rehabilitation","volume":"105","author":"Garratt","year":"2024","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1002\/clc.22481","article-title":"Exercise and Physical Activity for the Post-Aortic Dissection Patient: The Clinician\u2019s Conundrum","volume":"38","author":"Chaddha","year":"2015","journal-title":"Clin. Cardiol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s11556-020-00239-5","article-title":"The effect of e-health interventions promoting physical activity in older people: A systematic review and meta-analysis","volume":"17","author":"Kwan","year":"2020","journal-title":"Eur. Rev. Aging Phys. Act."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/s00595-011-0060-1","article-title":"Sleep disorders and aortic dissection in a working population","volume":"42","author":"Hata","year":"2012","journal-title":"Surg. Today"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1177\/1559827619867677","article-title":"Cognitive-Behavioral Therapy for Insomnia: An Effective and Underutilized Treatment for Insomnia","volume":"13","author":"Rossman","year":"2019","journal-title":"Am. J. Lifestyle Med."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1249\/MSS.0000000000001947","article-title":"Wearable Sleep Technology in Clinical and Research Settings","volume":"51","author":"Cellini","year":"2019","journal-title":"Med. Sci. Sports Exerc."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/3\/859\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T10:37:33Z","timestamp":1759919853000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/3\/859"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,28]]},"references-count":26,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,2]]}},"alternative-id":["jcm14030859"],"URL":"https:\/\/doi.org\/10.3390\/jcm14030859","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,28]]}}}