{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T18:28:07Z","timestamp":1788805687743,"version":"build-2803163510"},"reference-count":37,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T00:00:00Z","timestamp":1738886400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Dysphonia, a common symptom after thyroid surgery, is most often caused by damage to the recurrent laryngeal nerve. Laryngeal electromyography (LEMG) is used as a qualitative diagnostic tool to distinguish neurological etiology from other causes of dysphonia. The purpose of this study is to establish the value of LEMG as a predictor factor in the recovery of unilateral recurrent paralysis post-thyroidectomy. Methods: This study included 11 patients with unilateral vocal fold palsy (UVFP) evidenced on the videostrobolaryngoscopy (VSL) after thyroidectomy. Electrical activity of thyroarytenoid (TA) muscles of the patients included in the study was recorded through LEMG and the prognosis of the lesions was classified as excellent, fair, or poor based on the presence of spontaneous activity and motor unit recruitment. Results: LEMG at the first clinic visit showed an excellent prognosis in three of the cases, a fair prognosis in three of the cases, and five of them indicated a poor prognosis. At 6 months after the first LEMG, patients with a poor prognosis were unchanged and showed no LEMG improvement. Those with an excellent prognosis showed an increased recruitment response, and LEMG was normal. In one patient with a fair prognosis and minimal spontaneous activity, LEMG recruitment decreased during reevaluation. The other two fair-prognosis patients had a normal LEMG. Conclusions: A correlation was found between LEMG findings and functional recovery of the vocal cords, demonstrating that the presence of spontaneous activity represents a negative prognostic factor. However, due to limited patient cohorts, the sensitivity of the LEMG as a prognostic tool in the functional recovery of the larynx is not yet established and requires further research.<\/jats:p>","DOI":"10.3390\/jcm14041047","type":"journal-article","created":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T05:04:33Z","timestamp":1738904673000},"page":"1047","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Laryngeal Electromyography as a Predictive Factor in the Evolution of Unilateral Recurrent Paralysis Post-Thyroidectomy"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5966-3314","authenticated-orcid":false,"given":"Shirley","family":"Tarabichi","sequence":"first","affiliation":[{"name":"Faculty of Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 20021 Bucharest, Romania"},{"name":"ENT&HNS Department, \u201cSf. Maria\u201d Clinical Hospital, 011172 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Codrut","family":"Sarafoleanu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 20021 Bucharest, Romania"},{"name":"ENT&HNS Department, \u201cSf. Maria\u201d Clinical Hospital, 011172 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"155","DOI":"10.3342\/ceo.2015.8.2.155","article-title":"The effect of total thyroidectomy on the speech production","volume":"8","author":"Hong","year":"2015","journal-title":"Clin. Exp. Otorhinolaryngol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1097\/00000658-200202000-00015","article-title":"Laryngeal recurrent nerve injury in surgery for benign thyroid diseases: Effect of nerve dissection and impact of individual surgeon in more than 27,000 nerves at risk","volume":"235","author":"Hermann","year":"2002","journal-title":"Ann. Surg."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jvoice.2017.09.012","article-title":"Vocal Changes Following Thyroid Surgery: Prospective Study of Objective and Subjective Parameters","volume":"33","author":"Cobeta","year":"2019","journal-title":"J. Voice"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"405","DOI":"10.4143\/crt.2017.012","article-title":"Development and Evaluation of a Korean Version of a Thyroid-Specific Quality-of-Life Questionnaire Scale in Thyroid Cancer Patients","volume":"50","author":"Ryu","year":"2018","journal-title":"Cancer Res. Treat."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.2967\/jnumed.115.161463","article-title":"Administration of Radioactive Iodine Therapy Within 1 Year After Total Thyroidectomy Does Not Affect Vocal Function","volume":"56","author":"Ryu","year":"2015","journal-title":"J. Nucl. Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1089\/thy.2013.0262","article-title":"How can we screen voice problems effectively in patients undergoing thyroid surgery?","volume":"23","author":"Park","year":"2013","journal-title":"Thyroid"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2503","DOI":"10.1007\/s00268-012-1667-0","article-title":"Early postoperative vocal function evaluation after thyroidectomy using thyroidectomy related voice questionnaire","volume":"36","author":"Chun","year":"2012","journal-title":"World J. Surg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1111\/j.1742-1241.2008.01875.x","article-title":"Diagnosis of recurrent laryngeal nerve palsy after thyroidectomy: A systematic review","volume":"63","author":"Jeannon","year":"2009","journal-title":"Int. J. Clin. Pract."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.jamcollsurg.2004.06.020","article-title":"Voice changes after thyroidectomy without recurrent laryngeal nerve injury","volume":"199","author":"Sinagra","year":"2004","journal-title":"J. Am. Coll. Surg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1046\/j.1365-2273.2002.00559.x","article-title":"The quality of life impact of dysphonia","volume":"27","author":"Wilson","year":"2002","journal-title":"Clin. Otolaryngol. Allied Sci."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Rosa, M.S., Dell\u2019Era, V., Campagnoli, M., Campini, S., Barozza, O., Borello, G., Garzaro, M., and Valletti, P.A. (2024). Vocal Outcome Following Thyroidectomy for Differentiated Thyroid Carcinoma. J. Clin. Med., 13.","DOI":"10.3390\/jcm13247576"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"E177","DOI":"10.1002\/lary.28148","article-title":"Measuring the impact of dysphonia on quality of life using health state preferences","volume":"130","author":"Naunheim","year":"2020","journal-title":"Laryngoscope"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1097\/00005537-200409000-00009","article-title":"Development and validation of the voice handicap index-10","volume":"114","author":"Rosen","year":"2004","journal-title":"Laryngoscope"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/S0892-1997(99)80010-1","article-title":"Validation of an instrument to measure voice-related quality of life (V-RQOL)","volume":"13","author":"Hogikyan","year":"1999","journal-title":"J. Voice"},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"TEQ Group (1990). EuroQol\u2014A new facility for the measurement of health-related quality of life. Health Policy, 16, 199\u2013208.","DOI":"10.1016\/0168-8510(90)90421-9"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1002\/hec.4730020305","article-title":"The RAND 36-Item Health Survey 1.0","volume":"2","author":"Hays","year":"1993","journal-title":"Health Econ."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1016\/j.otohns.2009.01.026","article-title":"Recommendations of the Neurolaryngology Study Group on laryngeal electromyography","volume":"140","author":"Blitzer","year":"2009","journal-title":"Otolaryngol. Head. Neck Surg."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1001\/archotol.127.2.155","article-title":"Prognostic value of laryngeal electromyography in vocal fold paralysis","volume":"127","author":"Sittel","year":"2001","journal-title":"Arch. Otolaryngol. Head. Neck Surg."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1016\/S0003-9993(03)00146-1","article-title":"Utility of laryngeal electromyography in predicting recovery after vocal fold paralysis","volume":"84","author":"Munin","year":"2003","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1002\/mus.10503","article-title":"Laryngeal electromyography: An evidence-based review","volume":"28","author":"Sataloff","year":"2003","journal-title":"Muscle Nerve"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1097\/MLG.0b013e3181671b2d","article-title":"Evaluation of peripheral vocal cord paralysis by electromyography","volume":"118","author":"Grosheva","year":"2008","journal-title":"Laryngoscope"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1177\/000348940911800709","article-title":"Diagnosis and prognosis of iatrogenic injury of the recurrent laryngeal nerve","volume":"118","author":"Hydman","year":"2009","journal-title":"Ann. Otol. Rhinol. Laryngol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1093\/brain\/66.4.237","article-title":"Three types of nerve injury","volume":"66","author":"Seddon","year":"1943","journal-title":"Brain"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1177\/019459989411100612","article-title":"A preliminary study of the prognostic role of electromyography in laryngeal paralysis","volume":"111","author":"Min","year":"1994","journal-title":"Otolaryngol. Head. Neck Surg."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1002\/lary.22354","article-title":"Laryngeal electromyography for prognosis of vocal fold palsy: A meta-analysis","volume":"122","author":"Rickert","year":"2012","journal-title":"Laryngoscope"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1002\/lary.21884","article-title":"Quantitative electromyography improves prediction in vocal fold paralysis","volume":"122","author":"Smith","year":"2012","journal-title":"Laryngoscope"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1002\/lary.24980","article-title":"Laryngeal electromyography and prognosis of unilateral vocal fold paralysis--a long-term prospective study","volume":"125","author":"Wang","year":"2015","journal-title":"Laryngoscope"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1001\/archotol.134.4.380","article-title":"Prognostic indicators of unilateral vocal fold paralysis","volume":"134","author":"Wang","year":"2008","journal-title":"Arch. Otolaryngol. Head. Neck Surg."},{"key":"ref_29","first-page":"27","article-title":"Recovery of laryngeal function after intraoperative injury to the recurrent laryngeal nerve","volume":"4","author":"Mattsson","year":"2015","journal-title":"Gland. Surg."},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Blum, A.S., and Rutkove, S.B. (2007). Electrophysiology of Myopathy, B.T. The Clinical Neurophysiology Primer, Humana Press.","DOI":"10.1007\/978-1-59745-271-7"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/S0030-6665(20)31275-5","article-title":"Repair of the recurrent laryngeal nerve","volume":"23","author":"Crumley","year":"1990","journal-title":"Otolaryngol. Clin. North. Am."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1002\/mus.21124","article-title":"Collateral reinnervation by the superior laryngeal nerve after recurrent laryngeal nerve injury","volume":"38","author":"Hydman","year":"2008","journal-title":"Muscle Nerve"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s11420-005-0124-0","article-title":"EMG: Myths and facts","volume":"2","author":"Feinberg","year":"2006","journal-title":"HSS J."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"500","DOI":"10.3109\/00016486709139135","article-title":"The sternohyoid muscle during phonation. Electromyographic studies","volume":"64","author":"Hirano","year":"1967","journal-title":"Acta Otolaryngol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1288\/00005537-198511000-00005","article-title":"Predictive value of laryngeal electromyography in patients with vocal cord paralysis of neurogenic origin","volume":"95","author":"Parnes","year":"1985","journal-title":"Laryngoscope"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1002\/mus.880160917","article-title":"Use of laryngeal electromyography in prediction of recovery after vocal cord paralysis","volume":"16","author":"Gupta","year":"1993","journal-title":"Muscle Nerve"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1002\/(SICI)1097-4598(199804)21:4<552::AID-MUS23>3.0.CO;2-Y","article-title":"The value of laryngeal electromyography in vocal cord paralysis","volume":"21","author":"Elez","year":"1998","journal-title":"Muscle Nerve"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/4\/1047\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T16:28:38Z","timestamp":1760027318000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/4\/1047"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,7]]},"references-count":37,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,2]]}},"alternative-id":["jcm14041047"],"URL":"https:\/\/doi.org\/10.3390\/jcm14041047","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,7]]}}}