{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T19:33:54Z","timestamp":1791488034225,"version":"4.3.4"},"reference-count":60,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T00:00:00Z","timestamp":1741305600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Mental illnesses following an acute myocardial infarction (AMI) are a growing concern, as they are associated with worse outcomes for AMI patients. Our understanding of the prevalence of mental illnesses after an AMI is incomplete, as most studies investigate depression while overlooking other conditions like anxiety and PTSD. Existing studies often rely on patient-reported questionnaires for mental illness diagnoses, a method that can be subjective. To address this, we conducted a systematic review and meta-analysis to determine the prevalence and risk factors of depression, anxiety, and PTSD after AMI, including only studies with formal mental illness diagnoses. Methods: Searches in MEDLINE, EMBASE, and PsycINFO up to 23 January 2025 identified 23 qualifying studies that assessed the prevalence of depression, anxiety, and PTSD after AMI, with cases defined exclusively by formal diagnoses established through psychiatrist-administered structured interviews according to the Diagnostic and Statistical Manual for Mental Disorders (DSM) criteria (versions III to V). For each outcome, the pooled prevalence was estimated using meta-analyses of proportions with random-effects models. If significant heterogeneity was detected, subgroup analyses and meta-regression were performed to explore the factors contributing to this heterogeneity. Results: A total of 25 studies were included in the meta-analysis. Among the 20 studies included, the pooled prevalence of depression after AMI was 23.58% (95% CI: 22.86%; 24.32%). When stratified by time since AMI, the prevalence was 19.46% (95% CI: 15.47%; 24.19%) for those assessed within 3 months and 14.87% (95% CI: 9.55%; 22.43%) for those assessed after 3 months. The pooled prevalence of anxiety (seven studies) and PTSD (three studies) was 11.96% (95% CI: 6.15; 21.96%) and 10.26% (95% CI: 5.49%; 18.36%), respectively. Further pooled prevalence subgroup analysis of depression and anxiety revealed significantly higher rates in the female sex (29.89%, 95% CI: 21.85; 39.41%), in those with hypertension (25.01%, 95% CI: 21.68; 28.67%), diabetes (25.01%, 95% CI: 21.68; 28.67%), or hyperlipidemia (28.96% 95% CI: 23.44; 35.17%), and in smokers (25.23%., 95% CI: 19.48; 32.00%), while the pooled prevalence of depression is higher in unmarried (35.44%, 95% CI: 19.61; 55.26%) than married individuals (28.63%, 95% CI: 18.67; 41.20%) and in those with a history of depression (57.41%, 95% CI: 31.47; 78.92%). The results of the meta-regression indicated that a prior history of depression was a significant predictor of depression prevalence (p = 0.0035, regression coefficient 1.54). Conclusions: The prevalence of mental illnesses, including depression, anxiety, and PTSD, is notable following an AMI. Identified risk factors encompass female sex, hypertension, diabetes mellitus, hyperlipidemia, smoking, a history of depressive illness, and social context.<\/jats:p>","DOI":"10.3390\/jcm14061786","type":"journal-article","created":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T04:29:59Z","timestamp":1741321799000},"page":"1786","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Prevalence of Depression, Anxiety and Post-Traumatic Stress Disorder (PTSD) After Acute Myocardial Infarction: A Systematic Review and Meta-Analysis"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1114-7038","authenticated-orcid":false,"given":"Ray Junrui","family":"Chong","sequence":"first","affiliation":[{"name":"Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunrui","family":"Hao","sequence":"additional","affiliation":[{"name":"Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8614-8664","authenticated-orcid":false,"given":"Emily Wei Qi","family":"Tan","sequence":"additional","affiliation":[{"name":"Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 639798, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace Jing Le","family":"Mok","sequence":"additional","affiliation":[{"name":"Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 639798, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2764-2869","authenticated-orcid":false,"given":"Ching-Hui","family":"Sia","sequence":"additional","affiliation":[{"name":"Department of Cardiology, National University Heart Centre Singapore, Singapore 119074, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamie Sin Ying","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Medicine, National University Hospital, Singapore 119074, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark Yan Yee","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, National University Heart Centre Singapore, Singapore 119074, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4338-3876","authenticated-orcid":false,"given":"Andrew Fu Wah","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Singapore General Hospital, Singapore 169608, Singapore"},{"name":"Pre-Hospital & Emergency Research Centre, Duke-National University of Singapore Medical School, Singapore 169857, Singapore"},{"name":"Centre for Population Health Research and Implementation, SingHealth Regional Health System, Singapore 117549, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,3,7]]},"reference":[{"key":"ref_1","unstructured":"World Health Organisation (2024, January 15). Cardiovascular Diseases (CVDs): World Health Organisation. Available online: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/cardiovascular-diseases-(cvds)."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"56","DOI":"10.4103\/ijpvm.IJPVM_122_20","article-title":"The Reduction of Mortality in Acute Myocardial Infarction: From Bed Rest to Future Directions","volume":"13","author":"Laforgia","year":"2022","journal-title":"Int. J. Prev. Med."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Forslund, T., Kosidou, K., Wicks, S., and Dalman, C. (2020). Trends in psychiatric diagnoses, medications and psychological therapies in a large Swedish region: A population-based study. BMC Psychiatry, 20.","DOI":"10.1186\/s12888-020-02749-z"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1161\/CIRCOUTCOMES.111.961896","article-title":"Depression and rehospitalization following acute myocardial infarction","volume":"4","author":"Reese","year":"2011","journal-title":"Circ. Cardiovasc. Qual. Outcomes"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.genhosppsych.2011.02.007","article-title":"Prognostic association of depression following myocardial infarction with mortality and cardiovascular events: A meta-analysis of 25 years of research","volume":"33","author":"Meijer","year":"2011","journal-title":"Gen. Hosp. Psychiatry"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1097\/01.hjr.0000214606.60995.46","article-title":"Myocardial infarction and post-traumatic stress disorder: Frequency, outcome, and atherosclerotic mechanisms","volume":"13","author":"Gander","year":"2006","journal-title":"Eur. J. Cardiovasc. Prev. Rehabil."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1002\/clc.23605","article-title":"Anxiety and prognosis of patients with myocardial infarction: A meta-analysis","volume":"44","author":"Wen","year":"2021","journal-title":"Clin. Cardiol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"e14596","DOI":"10.1097\/MD.0000000000014596","article-title":"Prevalence of depression in myocardial infarction: A PRISMA-compliant meta-analysis","volume":"98","author":"Feng","year":"2019","journal-title":"Medicine"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: An updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1097\/JGP.0b013e318190b901","article-title":"An examination of the \u201cgold standard\u201d diagnosis of major depression in aged-care settings","volume":"17","author":"Davison","year":"2009","journal-title":"Am. J. Geriatr. Psychiatry"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1186\/s12955-020-01347-7","article-title":"Quality of life assessment instruments for adults: A systematic review of population-based studies","volume":"18","author":"Pequeno","year":"2020","journal-title":"Health Qual. Life Outcomes"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/j.1525-1497.2005.00269.x","article-title":"Prevalence of depression in survivors of acute myocardial infarction","volume":"21","author":"Thombs","year":"2006","journal-title":"J. Gen. Intern. Med."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1001\/archinte.1989.00390080059014","article-title":"The nature and course of depression following myocardial infarction","volume":"149","author":"Schleifer","year":"1989","journal-title":"Arch. Intern. Med."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"33","DOI":"10.2190\/CJ9D-32C2-8CM7-FT3D","article-title":"Depression following myocardial infarction","volume":"22","author":"Forrester","year":"1992","journal-title":"Int. J. Psychiatry Med."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1097\/00006842-199603000-00001","article-title":"Major depression before and after myocardial infarction: Its nature and consequences","volume":"58","author":"Lesperance","year":"1996","journal-title":"Psychosom. Med."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1046\/j.1532-5415.2002.50205.x","article-title":"The significance of depression in older patients after myocardial infarction","volume":"50","author":"Romanelli","year":"2002","journal-title":"J. Am. Geriatr. Soc."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/S0002-8703(03)00083-8","article-title":"Cognitive and somatic symptoms of depression are associated with medical comorbidity in patients after acute myocardial infarction","volume":"146","author":"Watkins","year":"2003","journal-title":"Am. Heart J."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1136\/jnnp.74.5.581","article-title":"A comparative study into the one year cumulative incidence of depression after stroke and myocardial infarction","volume":"74","author":"Aben","year":"2003","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0022-3999(03)00380-5","article-title":"One year cumulative incidence of depression following myocardial infarction and impact on cardiac outcome","volume":"56","author":"Strik","year":"2004","journal-title":"J. Psychosom. Res."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1176\/appi.ajp.161.2.271","article-title":"The association between major depression and levels of soluble intercellular adhesion molecule 1, interleukin-6, and C-reactive protein in patients with recent acute coronary syndromes","volume":"161","author":"Lesperance","year":"2004","journal-title":"Am. J. Psychiatry"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/j.ahj.2004.08.007","article-title":"Depression and heart failure in patients with a new myocardial infarction","volume":"149","author":"Powell","year":"2005","journal-title":"Am. Heart J."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.genhosppsych.2005.05.007","article-title":"Depression following myocardial infarction: First-ever versus ongoing and recurrent episodes","volume":"27","author":"Spijkerman","year":"2005","journal-title":"Gen. Hosp. Psychiatry"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1159\/000095440","article-title":"Recognizing increased risk of depressive comorbidity after myocardial infarction: Looking for 4 symptoms of anxiety-depression","volume":"75","author":"Denollet","year":"2006","journal-title":"Psychother Psychosom"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1192\/bjp.bp.106.028647","article-title":"Effects of antidepressant treatment following myocardial infarction","volume":"190","author":"Honig","year":"2007","journal-title":"Br. J. Psychiatry"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.amjcard.2007.10.021","article-title":"Effect of depression on late (8 years) mortality after myocardial infarction","volume":"101","author":"Parakh","year":"2008","journal-title":"Am. J. Cardiol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1016\/j.amjcard.2009.02.014","article-title":"Relation of anxiety and adherence to risk-reducing recommendations following myocardial infarction","volume":"103","author":"Kuhl","year":"2009","journal-title":"Am. J. Cardiol."},{"key":"ref_27","first-page":"636","article-title":"Depression in patients of myocardial infarction--a cross-sectional study in northern India","volume":"59","author":"Agarwal","year":"2011","journal-title":"J. Assoc. Physicians India"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.genhosppsych.2011.09.016","article-title":"Anxiety and depression in patients with myocardial infarction: Findings from a centre in India","volume":"34","author":"Sarkar","year":"2012","journal-title":"Gen. Hosp. Psychiatry"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1192\/bjp.bp.111.103549","article-title":"Myocardial infarction and generalised anxiety disorder: 10-year follow-up","volume":"200","author":"Roest","year":"2012","journal-title":"Br. J. Psychiatry"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.comppsych.2014.11.001","article-title":"Is there any difference between the early age myocardial infarction and late age myocardial infarction in terms of psychiatric morbidity in patients who have survived acute myocardial infarction?","volume":"57","author":"Annagur","year":"2015","journal-title":"Compr Psychiatry"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"e4464","DOI":"10.1097\/MD.0000000000004464","article-title":"Risk of anxiety and depressive disorders in patients with myocardial infarction: A nationwide population-based cohort study","volume":"95","author":"Feng","year":"2016","journal-title":"Medicine"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"102491","DOI":"10.1016\/j.janxdis.2021.102491","article-title":"Comparison of symptom-based versus self-reported diagnostic measures of anxiety and depression disorders in the GLAD and COPING cohorts","volume":"85","author":"Davies","year":"2022","journal-title":"J. Anxiety Disord."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1920201","DOI":"10.1080\/20008198.2021.1920201","article-title":"Assessment of trimethylamine N-oxide (TMAO) as a potential biomarker of severe stress in patients vulnerable to posttraumatic stress disorder (PTSD) after acute myocardial infarction","volume":"12","author":"Baranyi","year":"2021","journal-title":"Eur. J. Psychotraumatol."},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Edmondson, D., Shaffer, J.A., Denton, E.G., Shimbo, D., and Clemow, L. (2012). Posttraumatic stress and myocardial infarction risk perceptions in hospitalized acute coronary syndrome patients. Front. Psychol., 3.","DOI":"10.3389\/fpsyg.2012.00144"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1016\/0002-8703(91)90144-7","article-title":"Digitalis and beta-blocking agents: Effects on depression following myocardial infarction","volume":"121","author":"Schleifer","year":"1991","journal-title":"Am. Heart J."},{"key":"ref_36","first-page":"547","article-title":"Depression and prognosis following hospital admission because of acute myocardial infarction","volume":"168","author":"Lauzon","year":"2003","journal-title":"CMAJ"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.1547-5069.1988.tb00074.x","article-title":"Identifying depression in medical patients","volume":"20","author":"Davis","year":"1988","journal-title":"Image J. Nurs. Sch."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"111141","DOI":"10.1016\/j.jpsychores.2022.111141","article-title":"Co-prevalence and incidence of myocardial infarction and\/or stroke in patients with depression and\/or anxiety: A systematic review and meta-analysis","volume":"165","author":"Aw","year":"2023","journal-title":"J. Psychosom. Res."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"550","DOI":"10.5603\/CJ.a2017.0123","article-title":"Morning and afternoon serum cortisol level in patients with post-myocardial infarction depression","volume":"26","author":"Wilkowska","year":"2019","journal-title":"Cardiol. J."},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Garrels, E., Kainth, T., Silva, B., Yadav, G., Gill, G., Salehi, M., and Gunturu, S. (2023). Pathophysiological mechanisms of post-myocardial infarction depression: A narrative review. Front. Psychiatry, 14.","DOI":"10.3389\/fpsyt.2023.1225794"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Thong, E.H.E., Quek, E.J.W., Loo, J.H., Yun, C.-Y., Teo, Y.N., Teo, Y.H., Leow, A.S.T., Li, T.Y.W., Sharma, V.K., and Tan, B.Y.Q. (2023). Acute Myocardial Infarction and Risk of Cognitive Impairment and Dementia: A Review. Biology, 12.","DOI":"10.3390\/biology12081154"},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Fioranelli, M., Roccia, M.G., Przybylek, B., and Garo, M.L. (2023). The Role of Brain-Derived Neurotrophic Factor (BDNF) in Depression and Cardiovascular Disease: A Systematic Review. Life, 13.","DOI":"10.3390\/life13101967"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S0033-3182(09)70857-6","article-title":"Sex differences in the prevalence of post-stroke depression: A systematic review","volume":"50","author":"Poynter","year":"2009","journal-title":"Psychosomatics"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1097\/01.psy.0000164013.55453.05","article-title":"Gender differences in the link between depression and cardiovascular disease","volume":"67","author":"Naqvi","year":"2005","journal-title":"Psychosom. Med."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1037\/0022-3514.77.5.1061","article-title":"Explaining the gender difference in depressive symptoms","volume":"77","author":"Larson","year":"1999","journal-title":"J. Pers. Soc. Psychol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1001\/archinte.166.8.876","article-title":"Depressive symptoms after acute myocardial infarction: Evidence for highest rates in younger women","volume":"166","author":"Mallik","year":"2006","journal-title":"Arch. Intern. Med."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"31","DOI":"10.31887\/DCNS.2018.20.1\/mdehert","article-title":"The intriguing relationship between coronary heart disease and mental disorders","volume":"20","author":"Detraux","year":"2018","journal-title":"Dialogues Clin. Neurosci."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"102457","DOI":"10.1016\/j.cpcardiol.2024.102457","article-title":"Sex- and gender-related disparities in chest pain syndromes: The feminine mystique of chest pain","volume":"49","author":"Angeli","year":"2024","journal-title":"Curr. Probl. Cardiol."},{"key":"ref_49","first-page":"120","article-title":"The association between Diabetes mellitus and Depression","volume":"9","author":"Kobylinska","year":"2016","journal-title":"J. Med. Life"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1038\/nrendo.2009.106","article-title":"Stress and disorders of the stress system","volume":"5","author":"Chrousos","year":"2009","journal-title":"Nat. Rev. Endocrinol."},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"Wu, Z., Yue, Q., Zhao, Z., Wen, J., Tang, L., Zhong, Z., Yang, J., Yuan, Y., and Zhang, X. (2023). A cross-sectional study of smoking and depression among US adults: NHANES (2005\u20132018). Front. Public Health, 11.","DOI":"10.3389\/fpubh.2023.1081706"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1111\/add.15390","article-title":"The associations of smoking dependence motives with depression among daily smokers","volume":"116","author":"Piirtola","year":"2021","journal-title":"Addiction"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1001\/archinte.160.12.1818","article-title":"Patients with depression are less likely to follow recommendations to reduce cardiac risk during recovery from a myocardial infarction","volume":"160","author":"Ziegelstein","year":"2000","journal-title":"Arch. Intern. Med."},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Murphy, B., Le Grande, M., Alvarenga, M., Worcester, M., and Jackson, A. (2019). Anxiety and Depression After a Cardiac Event: Prevalence and Predictors. Front. Psychol., 10.","DOI":"10.3389\/fpsyg.2019.03010"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"3106","DOI":"10.1001\/jama.289.23.3106","article-title":"Effects of treating depression and low perceived social support on clinical events after myocardial infarction: The Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Randomized Trial","volume":"289","author":"Berkman","year":"2003","journal-title":"JAMA"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1002\/jts.22591","article-title":"Posttraumatic Stress Disorder Following Myocardial Infarction: A Systematic Review","volume":"34","author":"Tarquinio","year":"2021","journal-title":"J. Trauma. Stress."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/S0002-9149(01)01675-7","article-title":"Even minimal symptoms of depression increase mortality risk after acute myocardial infarction","volume":"88","author":"Bush","year":"2001","journal-title":"Am. J. Cardiol."},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Sreenivasan, J., Kaul, R., Khan, M.S., Malik, A., Usman, M.S., and Michos, E.D. (2022). Mental health disorders and readmissions following acute myocardial infarction in the United States. Sci. Rep., 12.","DOI":"10.1038\/s41598-022-07234-z"},{"key":"ref_59","doi-asserted-by":"crossref","unstructured":"Sun, W., Gholizadeh, L., Perry, L., and Kang, K. (2022). Predicting Return to Work Following Myocardial Infarction: A Prospective Longitudinal Cohort Study. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph19138032"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"e9","DOI":"10.1161\/CIR.0000000000001168","article-title":"2023 AHA\/ACC\/ACCP\/ASPC\/NLA\/PCNA Guideline for the Management of Patients With Chronic Coronary Disease: A Report of the American Heart Association\/American College of Cardiology Joint Committee on Clinical Practice Guidelines","volume":"148","author":"Virani","year":"2023","journal-title":"Circulation"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/6\/1786\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T16:48:41Z","timestamp":1760028521000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/6\/1786"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,7]]},"references-count":60,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2025,3]]}},"alternative-id":["jcm14061786"],"URL":"https:\/\/doi.org\/10.3390\/jcm14061786","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,7]]}}}