{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:01:49Z","timestamp":1760058109997,"version":"build-2065373602"},"reference-count":39,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T00:00:00Z","timestamp":1742169600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: satisfactory sagittal alignment when treating degenerative spondylolisthesis of the lumbar spine (DSLS) may produce better clinical and radiographic outcomes compared to treatment focused solely on isolated segments when indicated. Ghailane et al. proposed a treatment guideline based on their classification system. The aim of this study was to investigate the impact of adherence to Ghailane\u2013Gille (GG) treatment guidelines on surgical outcomes in patients with DSLS. Methods: A monocentric retrospective cohort analysis was performed from 2021 to September 2024. Data were collected from patients treated for DSLS, covering the period from baseline to one-year follow-up. Patients were divided into two groups based on GG treatment guidelines: the \u201cMatch group\u201d (patients who underwent surgery following GG guidelines) and the \u201cMismatch group\u201d (patients who did not adhere to these guidelines). Preoperative and postoperative clinical outcomes, patient satisfaction, and operative parameters were collected and compared between groups. Results: A total of 80 patients were enrolled, with 52 in the Match group and 28 in the Mismatch group. At baseline, the Oswestry Disability Index (ODI) score demonstrated significant variation among classification subtypes and a positive correlation. The Match group exhibited a significant reduction in ODI scores one year postoperatively and maintained high levels of satisfaction; no significant intraoperative differences were noted. Additionally, patients in the Mismatch group were more frequently classified as American Society of Anesthesiologists (ASA) III compared to the Match group (70% vs. 30%), suggesting clinicians\u2019 hesitance to fully implement GG guidelines in aggressive treatment strategies for those patients. Conclusions: Adhering to the GG treatment guidelines for restoring sagittal alignment in DSLS patients is associated with decreased ODI scores regardless of age, ensuring patient satisfaction at one-year follow-up. This approach could potentially benefit ASA III patients as well.<\/jats:p>","DOI":"10.3390\/jcm14062041","type":"journal-article","created":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T08:57:02Z","timestamp":1742201822000},"page":"2041","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Does Adherence to Treatment Guidelines from the Ghailane\u2013Gille Classification for Degenerative Spondylolisthesis of the Lumbar Spine Impact Surgical Outcomes? A Match\u2013Mismatch Study"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3401-1838","authenticated-orcid":false,"given":"Soufiane","family":"Ghailane","sequence":"first","affiliation":[{"name":"Department of Spinal Surgery Unit, H\u00f4pital Priv\u00e9 Francheville, 24000 P\u00e9rigueux, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthieu","family":"Campana","sequence":"additional","affiliation":[{"name":"Department of Spinal Surgery Unit, H\u00f4pital Priv\u00e9 Francheville, 24000 P\u00e9rigueux, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivier","family":"Gille","sequence":"additional","affiliation":[{"name":"Department of Spinal Surgery Unit 1, Universit\u00e9 de Bordeaux, Bordeaux University Hospital, C.H.U. Tripode Pellegrin, Place Am\u00e9lie Raba L\u00e9on, 33076 Bordeaux, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Houssam","family":"Bouloussa","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Missouri-Kansas City, 2301 Holmes Street, Kansas City, MO 64108, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e9ment","family":"Jacquemin","sequence":"additional","affiliation":[{"name":"Department of Spinal Surgery Unit, H\u00f4pital Priv\u00e9 Francheville, 24000 P\u00e9rigueux, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Etienne","family":"Castelain","sequence":"additional","affiliation":[{"name":"Department of Spinal Surgery Unit, H\u00f4pital Priv\u00e9 Francheville, 24000 P\u00e9rigueux, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0074-9244","authenticated-orcid":false,"given":"Vincent","family":"Challier","sequence":"additional","affiliation":[{"name":"Department of Spinal Surgery Unit, H\u00f4pital Priv\u00e9 Francheville, 24000 P\u00e9rigueux, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,3,17]]},"reference":[{"key":"ref_1","first-page":"39","article-title":"Lumbar Degenerative Spondylolisthesis Epidemiology: A Systematic Review with a Focus on Gender-Specific and Age-Specific Prevalence","volume":"11","author":"Wang","year":"2017","journal-title":"J. Orthop. Transl."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1097\/01.brs.0000250979.12398.96","article-title":"Degenerative Lumbar Spondylolisthesis: An Epidemiological Perspective: The Copenhagen Osteoarthritis Study","volume":"32","author":"Jacobsen","year":"2007","journal-title":"Spine"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.nec.2019.02.009","article-title":"Summary of Guidelines for the Treatment of Lumbar Spondylolisthesis","volume":"30","author":"Chan","year":"2019","journal-title":"Neurosurg. Clin."},{"key":"ref_4","first-page":"371","article-title":"Spondylolisthesis","volume":"54","author":"Meyerding","year":"1932","journal-title":"Surg. Gynecol. Obs."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"194","DOI":"10.3171\/spi.2000.93.2.0194","article-title":"Nonsurgically Managed Patients with Degenerative Spondylolisthesis: A 10-to 18-Year Follow-up Study","volume":"93","author":"Matsunaga","year":"2000","journal-title":"J. Neurosurg. Spine"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1016\/j.spinee.2014.03.045","article-title":"Clinical and Radiographic Degenerative Spondylolisthesis (CARDS) Classification","volume":"15","author":"Kepler","year":"2015","journal-title":"Spine J."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"178","DOI":"10.3171\/2014.11.SPINE1426","article-title":"Defining the Inherent Stability of Degenerative Spondylolisthesis: A Systematic Review","volume":"23","author":"Simmonds","year":"2015","journal-title":"J. Neurosurg. Spine"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"E391","DOI":"10.1097\/BSD.0000000000000970","article-title":"Degenerative Spondylolisthesis: When to Fuse and When Not to? A New Scoring System","volume":"33","author":"Kulkarni","year":"2020","journal-title":"Clin. Spine Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"2309499019885190","DOI":"10.1177\/2309499019885190","article-title":"Global Sagittal Spinal Alignment in Patients with Degenerative Low-Grade Lumbar Spondylolisthesis","volume":"27","author":"Kobayashi","year":"2019","journal-title":"J. Orthop. Surg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1007\/s00586-011-1928-x","article-title":"Biomechanical Analysis of the Spino-Pelvic Organization and Adaptation in Pathology","volume":"20","author":"Roussouly","year":"2011","journal-title":"Eur. Spine J."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Kim, M.K., Lee, S.-H., Kim, E.-S., Eoh, W., Chung, S.-S., and Lee, C.-S. (2011). The Impact of Sagittal Balance on Clinical Results after Posterior Interbody Fusion for Patients with Degenerative Spondylolisthesis: A Pilot Study. BMC Musculoskelet. Disord., 12.","DOI":"10.1186\/1471-2474-12-69"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"448","DOI":"10.3171\/2016.9.SPINE1680","article-title":"Influence of Postoperative Sagittal Balance and Spinopelvic Parameters on the Outcome of Patients Surgically Treated for Degenerative Lumbar Spondylolisthesis","volume":"26","author":"Radovanovic","year":"2017","journal-title":"J. Neurosurg. Spine"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1007\/s00586-006-0294-6","article-title":"Sagittal Balance of the Pelvis-Spine Complex and Lumbar Degenerative Diseases. A Comparative Study about 85 Cases","volume":"16","author":"Barrey","year":"2007","journal-title":"Eur. Spine J."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"5971937","DOI":"10.1155\/2020\/5971937","article-title":"Analysis of Spinopelvic Sagittal Balance and Persistent Low Back Pain (PLBP) for Degenerative Spondylolisthesis (DS) Following Posterior Lumbar Interbody Fusion (PLIF)","volume":"2020","author":"He","year":"2020","journal-title":"Pain Res. Manag."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1097\/BRS.0000000000004374","article-title":"Preoperative Patient-Reported Outcomes Are Not Associated with Sagittal and Spinopelvic Alignment in Degenerative Lumbar Spondylolisthesis","volume":"47","author":"Karim","year":"2022","journal-title":"Spine"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1007\/s00586-024-08248-z","article-title":"Radiographic and Surgery-Related Predictive Factors for Increased Segmental Lumbar Lordosis Following Lumbar Fusion Surgery in Patients with Degenerative Lumbar Spondylolisthesis","volume":"33","author":"Wang","year":"2024","journal-title":"Eur. Spine J."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1007\/s00586-023-07994-w","article-title":"Correction: Degenerative Lumbar Spondylolisthesis: Review of Current Classifications and Proposal of a Novel Classification System","volume":"33","author":"Rangwalla","year":"2024","journal-title":"Eur. Spine J."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"3096","DOI":"10.1007\/s00586-017-5275-4","article-title":"A New Classification System for Degenerative Spondylolisthesis of the Lumbar Spine","volume":"26","author":"Gille","year":"2017","journal-title":"Eur. Spine J."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.jspd.2017.12.001","article-title":"Radiographic Classification for Degenerative Spondylolisthesis of the Lumbar Spine Based on Sagittal Balance: A Reliability Study","volume":"6","author":"Ghailane","year":"2018","journal-title":"Spine Deform."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"2224","DOI":"10.1097\/BRS.0b013e3181ee6bd4","article-title":"Adult Spinal Deformity\u2014Postoperative Standing Imbalance: How Much Can You Tolerate? An Overview of Key Parameters in Assessing Alignment and Planning Corrective Surgery","volume":"35","author":"Schwab","year":"2010","journal-title":"Spine"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1007\/s00586-014-3395-7","article-title":"Pelvic Retroversion Is the Key Protective Mechanism of L4\u20135 Degenerative Spondylolisthesis","volume":"24","author":"Liu","year":"2015","journal-title":"Eur. Spine J."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.2106\/JBJS.M.01459","article-title":"The T1 Pelvic Angle, a Novel Radiographic Measure of Global Sagittal Deformity, Accounts for Both Spinal Inclination and Pelvic Tilt and Correlates with Health-Related Quality of Life","volume":"96","author":"Protopsaltis","year":"2014","journal-title":"JBJS"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1056\/NEJMoa070302","article-title":"Surgical versus Nonsurgical Treatment for Lumbar Degenerative Spondylolisthesis","volume":"356","author":"Weinstein","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1097\/BRS.0000000000001857","article-title":"One-Level Lumbar Degenerative Spondylolisthesis and Posterior Approach: Is Transforaminal Lateral Interbody Fusion Mandatory?: A Randomized Controlled Trial With 2-Year Follow-Up","volume":"42","author":"Challier","year":"2017","journal-title":"Spine"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1136\/ebmed-2016-110474","article-title":"Fusion in Degenerative Spondylolisthesis Becomes Controversial\u2026 Again","volume":"21","author":"Weinstein","year":"2016","journal-title":"BMJ Evid. Based Med."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"S144","DOI":"10.1016\/j.spinee.2020.05.393","article-title":"291. Adjustment of the Global Alignment and Proportion Scores Accounting for Frailty in Adult Spinal Deformity Surgical Patients","volume":"20","author":"Passias","year":"2020","journal-title":"Spine J."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1007\/s00586-015-3778-4","article-title":"Sagittal Spinopelvic Alignment in 654 Degenerative Spondylolisthesis","volume":"24","author":"Ferrero","year":"2015","journal-title":"Eur. Spine J."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"E2","DOI":"10.3171\/2017.10.FOCUS17554","article-title":"Defining the Minimum Clinically Important Difference for Grade I Degenerative Lumbar Spondylolisthesis: Insights from the Quality Outcomes Database","volume":"44","author":"Asher","year":"2018","journal-title":"Neurosurg. Focus"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1016\/j.spinee.2017.05.021","article-title":"Radiological Lumbar Stenosis Severity Predicts Worsening Sagittal Malalignment on Full-Body Standing Stereoradiographs","volume":"17","author":"Buckland","year":"2017","journal-title":"Spine J."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.jspd.2018.08.016","article-title":"Short Lumbosacral Decompression Plus Fixation Does Not Change the Spinopelvic Balance on Patients With Moderate Degenerative Spondylolisthesis and Associated Spinal Stenosis","volume":"7","author":"Korovessis","year":"2019","journal-title":"Spine Deform."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"40S","DOI":"10.1177\/21925682211055096","article-title":"Pre-Operative Planning in Complex Deformities and Use of Patient-Specific UNiDTM Instrumentation","volume":"12","author":"Burger","year":"2022","journal-title":"Glob. Spine J."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/os.12282","article-title":"Patient-Specific Orthopaedic Implants","volume":"8","author":"Haglin","year":"2016","journal-title":"Orthop. Surg."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1007\/s00586-019-06236-2","article-title":"3D-Printed Spine Surgery Implants: A Systematic Review of the Efficacy and Clinical Safety Profile of Patient-Specific and off-the-Shelf Devices","volume":"29","author":"Burnard","year":"2020","journal-title":"Eur. Spine J."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1016\/j.spinee.2021.03.005","article-title":"Management of Degenerative Spondylolisthesis: Development of Appropriate Use Criteria","volume":"21","author":"Reitman","year":"2021","journal-title":"Spine J."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1007\/s00586-024-08157-1","article-title":"Evaluation of \u201cAppropriate Use Criteria\u201d for Surgical Decision-Making in Lumbar Degenerative Spondylolisthesis. A Controlled, Multicentre, Prospective Observational Study","volume":"33","author":"Mannion","year":"2024","journal-title":"Eur. Spine J."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"S34","DOI":"10.1016\/j.spinee.2022.06.080","article-title":"66. Can Classification Systems and Baseline Radiographic Findings Guide Surgical Technique Selection for Degenerative Spondylolisthesis?","volume":"22","author":"Baltic","year":"2022","journal-title":"Spine J."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1097\/00007632-199410000-00001","article-title":"The Use of the Percentage Change in Oswestry Disability Index Score as an Outcome Measure in Lumbar Spinal Surgery","volume":"19","author":"Little","year":"1994","journal-title":"Spine"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1080\/09638288.2016.1223177","article-title":"World Health Organization Disability Assessment Schedule 2.0: An International Systematic Review","volume":"39","author":"Federici","year":"2017","journal-title":"Disabil. Rehabil."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.apmr.2022.06.005","article-title":"Measurement Properties and Minimal Important Change of the World Health Organization Disability Assessment Schedule 2.0 in Persons with Low Back Pain: A Systematic Review","volume":"104","author":"Wong","year":"2023","journal-title":"Arch. Phys. Med. Rehabil."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/6\/2041\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T16:55:03Z","timestamp":1760028903000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/6\/2041"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,17]]},"references-count":39,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2025,3]]}},"alternative-id":["jcm14062041"],"URL":"https:\/\/doi.org\/10.3390\/jcm14062041","relation":{},"ISSN":["2077-0383"],"issn-type":[{"type":"electronic","value":"2077-0383"}],"subject":[],"published":{"date-parts":[[2025,3,17]]}}}