{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T13:38:49Z","timestamp":1781789929311,"version":"3.54.5"},"reference-count":32,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T00:00:00Z","timestamp":1742515200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ziemer Ophthalmics, Bern, Switzerland","award":["CPFEM-0003-BE"],"award-info":[{"award-number":["CPFEM-0003-BE"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: We report a consecutive prospective case series to obtain prospective safety and performance data of a low-energy femtosecond (FS)-laser for cataract surgery in children and to evaluate the applicability of the Bochum formula for capsulotomy diameter calculation. Methods: In pediatric lens surgery with implantation of a bag-in-the-lens intraocular lens (BIL IOL), anterior capsulotomies were performed using the FS-laser. Regression analysis was used to develop an age-dependent correction formula, and the Pearson correlation was used to evaluate the applicability of the Bochum formula. Surgery-related and ocular adverse events (AE) were recorded at 1 day, 1 week, 1 month, and 6 months postoperatively. Results: Thirteen eyes of 10 patients were included in the analysis, among them three cases of subluxated lenses. The mean age was 3.10 \u00b1 2.38 years (range: 4 months to 8 years). The linear bivalent regression yielded the following formula: 1.27 \u2212 0.014 \u00d7 patient age. Age-related formulas, such as the Bochum formula, are required to calculate the programmed capsulotomy diameter. No complications related to the FS-laser or ocular AEs were observed up to six months; in particular, no excessive shrinkage, retinal detachment, or unusual inflammation were identified. Conclusions: This study indicates that the use of the low-energy femtosecond laser for anterior capsulotomy in pediatric lens surgery is safe and contributes to improved reliability and feasibility. The confirmed age dependence of the enlargement factor of the capsulotomy diameter might be related to the higher capsular elasticity in pediatric eyes.<\/jats:p>","DOI":"10.3390\/jcm14072138","type":"journal-article","created":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T07:25:00Z","timestamp":1742541900000},"page":"2138","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prospective Case Series of Low-Energy Femtosecond Laser-Assisted Cataract Surgery in Pediatric Patients"],"prefix":"10.3390","volume":"14","author":[{"given":"Luc","family":"Van Os","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Antwerp University Hospital, B-2650 Edegem, Belgium"},{"name":"Department of Translational Neurosciences, University of Antwerp, B-2610 Antwerp, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iske","family":"De Backer","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Antwerp University Hospital, B-2650 Edegem, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michiel","family":"Taal","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Antwerp University Hospital, B-2650 Edegem, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2257-5855","authenticated-orcid":false,"given":"Marie-Jos\u00e9","family":"Tassignon","sequence":"additional","affiliation":[{"name":"Department of Translational Neurosciences, University of Antwerp, B-2610 Antwerp, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,3,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Wu, X., Long, E., Lin, H., and Liu, Y. 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