{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T21:38:18Z","timestamp":1765057098007,"version":"build-2065373602"},"reference-count":21,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T00:00:00Z","timestamp":1743120000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Research, Development, and Innovation Office of Hungary","award":["NKFIH K120536"],"award-info":[{"award-number":["NKFIH K120536"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Aims: The aim of this paper is to report 30-day and 1-year outcome data regarding the first 200 patients who underwent the TAVR procedure using the Myval THV system at our single centre. Methods: From November 2019 to October 2022, 200 consecutive patients underwent TAVR procedure. Outcomes were analysed according to the VARC-2 definitions, and device performance was assessed via transthoracic echocardiography. Data collection was approved by the local Ethical Committee. Results: The mean age of the cohort was 75.3 \u00b1 6.9 years, and 122 (61%) participants were male. The mean EuroSCORE II and STS was 5.4 \u00b1 5.4 and 5.8 \u00b1 3.8, respectively. The proportion of patients with a bicuspid aortic valve was 18%. The transfemoral access approach was the most common (surgical vs. percutaneous: 1% vs. 98%), and in two patients, surgical subclavian access was used. VARC-2 outcomes were as follows: 99% device success, 2% STROKE, 5% and 4.5% major and minor vascular complications, respectively, and a 29.5% rate of new permanent pacemaker implantation. At discharge, the incidence of aortic regurgitation grade II or above was 5.5% without relevant PVL (grade II or above 0.5%). In-hospital mortality was only 1%. At 1 year, the all-cause mortality rate was 8.5% (cardiac origin in three cases), and two patients had valve-related dysfunction requiring surgical aortic replacement. Conclusions: Our results showed excellent 30-day and 1-year outcomes regarding patient survival, technical success, and valve-related adverse events using the Myval transcatheter heart valve system. The limitations of our study comprise a single-centre design with retrospective data collection.<\/jats:p>","DOI":"10.3390\/jcm14072323","type":"journal-article","created":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T13:36:49Z","timestamp":1743169009000},"page":"2323","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Single-Centre Experience with the Balloon-Expandable Myval Transcatheter Aortic Valve System with the First 200 Patients: 30-Day and 1-Year Follow-Up"],"prefix":"10.3390","volume":"14","author":[{"given":"B\u00e1lint","family":"Kittka","sequence":"first","affiliation":[{"name":"Heart Institute, Medical School, University of P\u00e9cs, 13. Ifjus\u00e1g Str., H-7624 P\u00e9cs, Hungary"},{"name":"Szent\u00e1gothai Research Center, University of P\u00e9cs, H-7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8851-9637","authenticated-orcid":false,"given":"Bal\u00e1zs","family":"Magyari","sequence":"additional","affiliation":[{"name":"Heart Institute, Medical School, University of P\u00e9cs, 13. Ifjus\u00e1g Str., H-7624 P\u00e9cs, Hungary"},{"name":"Szent\u00e1gothai Research Center, University of P\u00e9cs, H-7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilona","family":"Goj\u00e1k","sequence":"additional","affiliation":[{"name":"Heart Institute, Medical School, University of P\u00e9cs, 13. Ifjus\u00e1g Str., H-7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00e1bor","family":"Kasza","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Medical School, University of P\u00e9cs, H-7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krist\u00f3f","family":"Sch\u00f6nfeld","sequence":"additional","affiliation":[{"name":"Heart Institute, Medical School, University of P\u00e9cs, 13. Ifjus\u00e1g Str., H-7624 P\u00e9cs, Hungary"},{"name":"Szent\u00e1gothai Research Center, University of P\u00e9cs, H-7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3 Botond","family":"Szap\u00e1ry","sequence":"additional","affiliation":[{"name":"Heart Institute, Medical School, University of P\u00e9cs, 13. Ifjus\u00e1g Str., H-7624 P\u00e9cs, Hungary"},{"name":"Szent\u00e1gothai Research Center, University of P\u00e9cs, H-7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mih\u00e1ly","family":"Simon","sequence":"additional","affiliation":[{"name":"Heart Institute, Medical School, University of P\u00e9cs, 13. Ifjus\u00e1g Str., H-7624 P\u00e9cs, Hungary"},{"name":"Szent\u00e1gothai Research Center, University of P\u00e9cs, H-7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rudolf","family":"Kiss","sequence":"additional","affiliation":[{"name":"Heart Institute, Medical School, University of P\u00e9cs, 13. Ifjus\u00e1g Str., H-7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Bertalan","sequence":"additional","affiliation":[{"name":"Heart Institute, Medical School, University of P\u00e9cs, 13. 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