{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T13:20:36Z","timestamp":1770297636164,"version":"3.49.0"},"reference-count":95,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T00:00:00Z","timestamp":1744243200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Alopecia areata (AA) contributes to clinically significant suffering, and impaired social functioning. Among AA patients, there is a clear impact of the disease on their sense of attractiveness and desirability as sexual partners. This review explores the development of sexual disorders among AA patients, highlighting their importance in the clinical diagnosis of comorbid health disorders with hair loss. Methods: A systematic review was conducted by searching electronic databases, including MEDLINE and Google Scholar, without date limitations, according to the PRISMA guidelines. Key search terms included \u201csexuality\u201d or \u201csexual health\u201d or \u201csexual dysfunction\u201d or \u201csexual disorder\u201d AND \u201calopecia areata\u201d. Data synthesis included findings from eight relevant studies. Results: Hair loss in the course of AA has a negative impact on the sexual sphere, significantly reducing the quality of life of patients and their partners. Proper sexual functioning is an integral part of every person, so special attention should be paid to the possibility of developing sexual dysfunction in the course of AA. Conclusions: Small sample sizes and heterogeneous populations make it difficult to draw firm conclusions. Continued research with standardized criteria for SD diagnosis and appropriately large cohorts will be essential to fully establish psychosexual disorders among AA patients.<\/jats:p>","DOI":"10.3390\/jcm14082602","type":"journal-article","created":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T07:41:51Z","timestamp":1744270911000},"page":"2602","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Sexual Dysfunction in Alopecia Areata: A Systematic Review"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4722-8531","authenticated-orcid":false,"given":"Piotr K.","family":"Krajewski","sequence":"first","affiliation":[{"name":"University Centre of General Dermatology and Oncodermatology, Wroclaw Medical University, 50-556 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4777-4024","authenticated-orcid":false,"given":"Aleksandra","family":"Z\u0142otowska","sequence":"additional","affiliation":[{"name":"University Centre of General Dermatology and Oncodermatology, Wroclaw Medical University, 50-556 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0766-6342","authenticated-orcid":false,"given":"Jacek C.","family":"Szepietowski","sequence":"additional","affiliation":[{"name":"Department of Dermatovenereology, 4th Military Hospital, 50-981 Wroclaw, Poland"},{"name":"Faculty of Medicine, Wroclaw University of Science and Technology, 50-377 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6315-5462","authenticated-orcid":false,"given":"David","family":"Saceda Corralo","sequence":"additional","affiliation":[{"name":"Servicio de Dermatolog\u00eda, Hospital Universitario Ram\u00f3n y Cajal, IRyCIS, 28034 Madrid, Spain"},{"name":"Hair Disorders Unit, Grupo Pedro Ja\u00e9n, 28002 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,10]]},"reference":[{"key":"ref_1","unstructured":"Lepe, K., Syed, H.A., and Zito, P.M. (2024). Alopecia Areata. StatPearls, StatPearls Publishing."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1177\/12034754231168839","article-title":"Alopecia Areata: An Updated Review for 2023","volume":"27","author":"Sibbald","year":"2023","journal-title":"J. Cutan. Med. Surg."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"799","DOI":"10.25259\/IJDVL_1093_2022","article-title":"Janus kinase inhibitors for alopecia areata: A narrative review","volume":"89","author":"Haughton","year":"2023","journal-title":"Indian. J. Dermatol. Venereol. Leprol."},{"key":"ref_4","first-page":"59","article-title":"Alopecia areata\u2014Current understanding and management","volume":"20","author":"Lintzeri","year":"2022","journal-title":"J. Dtsch. Dermatol. Ges."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/1346-8138.16207","article-title":"Alopecia areata: Current understanding of the pathophysiology and update on therapeutic approaches, featuring the Japanese Dermatological Association guidelines","volume":"49","author":"Fukuyama","year":"2022","journal-title":"J. Dermatol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"107","DOI":"10.2147\/CCID.S22767","article-title":"Alopecia areata: A new treatment plan","volume":"4","author":"Alsantali","year":"2011","journal-title":"Clin. Cosmet. Investig. Dermatol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1185\/030079905X61820","article-title":"The psychosocial impact of hair loss among men: A multinational European study","volume":"21","author":"Alfonso","year":"2005","journal-title":"Curr. Med. Res. Opin."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/BF01262572","article-title":"Changes in self-concept and body image during alopecia induced cancer chemotherapy","volume":"5","author":"Manthey","year":"1997","journal-title":"Support. Care Cancer."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1111\/jdv.20211","article-title":"Psychosocial and mental impact of alopecia areata: Analysis of the Danish Skin Cohort","volume":"39","author":"Clemmesen","year":"2025","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"397","DOI":"10.2147\/CCID.S53985","article-title":"Epidemiology and burden of alopecia areata: A systematic review","volume":"8","author":"Miteva","year":"2015","journal-title":"Clin. Cosmet. Investig. Dermatol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"955","DOI":"10.12740\/PP\/39064","article-title":"Psychological and psychopathological factors in alopecia areata","volume":"49","year":"2015","journal-title":"Psychiatr. Pol."},{"key":"ref_12","first-page":"286","article-title":"Sexual Health History: Techniques and Tips","volume":"101","author":"Savoy","year":"2020","journal-title":"Am. Fam. Physician"},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Chen, L., Huang, D.-D., Li, Y., Ma, C.-C., Shi, M., Su, B.-X., and Shi, G.-J. (2019). Male sexual dysfunction: A review of literature on its pathological mechanisms, potential risk factors, and herbal drug intervention. Biomed. Pharmacother., 112.","DOI":"10.1016\/j.biopha.2019.01.046"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"149","DOI":"10.4103\/2229-5178.182349","article-title":"Psychosexual disorders and dermatologists","volume":"7","author":"Narang","year":"2016","journal-title":"Indian. Dermatol. Online J."},{"key":"ref_15","first-page":"1","article-title":"Exploring the Psychosexual Impact of Dermatological Conditions and the Path Towards Integrated Interventions","volume":"441","author":"Li","year":"2024","journal-title":"Am. J. Clin. Med. Res."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1111\/jdv.18848","article-title":"Quality of life in children and adolescents with alopecia areata-A systematic review","volume":"37","author":"Prendke","year":"2023","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"n160","DOI":"10.1136\/bmj.n160","article-title":"PRISMA 2020 explanation and elaboration: Updated guidance and exemplars for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"17011","DOI":"10.1038\/nrdp.2017.11","article-title":"Alopecia areata","volume":"3","author":"Pratt","year":"2017","journal-title":"Nat. Rev. Dis. Primers"},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"S\u00e1nchez-Pellicer, P., Navarro-Moratalla, L., N\u00fa\u00f1ez-Delegido, E., Ag\u00fcera-Santos, J., and Navarro-L\u00f3pez, V. (2022). How Our Microbiome Influences the Pathogenesis of Alopecia Areata. Genes, 13.","DOI":"10.3390\/genes13101860"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/j.1365-4632.2007.03193.x","article-title":"Alopecia areata","volume":"46","author":"Wasserman","year":"2007","journal-title":"Int. J. Dermatol."},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Yamaguchi, H.L., Yamaguchi, Y., and Peeva, E. (2024). Pathogenesis of Alopecia Areata and Vitiligo: Commonalities and Differences. Int. J. Mol. Sci., 25.","DOI":"10.3390\/ijms25084409"},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Xu, W., Wan, S., Xie, B., and Song, X. (2023). Novel potential therapeutic targets of alopecia areata. Front. Immunol., 14.","DOI":"10.3389\/fimmu.2023.1148359"},{"key":"ref_23","first-page":"751","article-title":"Alopecia areata: Part 1: Pathogenesis, diagnosis, and prognosis","volume":"61","author":"Spano","year":"2015","journal-title":"Can. Fam. Physician"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"803","DOI":"10.2147\/CCID.S376096","article-title":"Alopecia Areata: Burden of Disease, Approach to Treatment, and Current Unmet Needs","volume":"16","author":"Alhanshali","year":"2023","journal-title":"Clin. Cosmet. Investig. Dermatol."},{"key":"ref_25","first-page":"e404","article-title":"Alopecia Areata. Current situation and perspectives. Alopecia areata","volume":"115","year":"2017","journal-title":"Actual. Y Perspect. Arch. Argent. Pediatr."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Minokawa, Y., Sawada, Y., and Nakamura, M. (2022). Lifestyle Factors Involved in the Pathogenesis of Alopecia Areata. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23031038"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1016\/j.jid.2018.05.027","article-title":"JAK Inhibitors for Treatment of Alopecia Areata","volume":"138","author":"Wang","year":"2018","journal-title":"J. Investig. Dermatol."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Mollaioli, D., Ciocca, G., Limoncin, E., Di Sante, S., Gravina, G.L., Carosa, E., Lenzi, A., and Jannini, E.A.F. (2020). Lifestyles and sexuality in men and women: The gender perspective in sexual medicine. Reprod. Biol. Endocrinol., 18.","DOI":"10.1186\/s12958-019-0557-9"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s11920-019-1090-4","article-title":"Sexuality and the Older Adult","volume":"21","author":"Srinivasan","year":"2019","journal-title":"Curr. Psychiatry Rep."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/00333549131282S101","article-title":"Understanding sexual health and its role in more effective prevention programs","volume":"128","author":"Douglas","year":"2013","journal-title":"Public. Health Rep."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/j.1743-6109.2007.00409.x","article-title":"Sexual dysfunctions: Classifications and definitions","volume":"4","author":"Hatzimouratidis","year":"2007","journal-title":"J. Sex. Med."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1080\/00224490209552124","article-title":"Sexual dysfunction: Overview of prevalence, etiological factors, and treatments","volume":"39","author":"Heiman","year":"2002","journal-title":"J. Sex. Res."},{"key":"ref_33","first-page":"553","article-title":"Management of sexual disorders","volume":"34","author":"Kok","year":"1993","journal-title":"Singapore Med. J."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1017\/S109285291200017X","article-title":"Female sexual disorders: Assessment, diagnosis, and treatment","volume":"16","author":"Kingsberg","year":"2011","journal-title":"CNS Spectr."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"37533","DOI":"10.52965\/001c.37533","article-title":"Male Sexual Dysfunction","volume":"10","author":"Anderson","year":"2022","journal-title":"Health Psychol. Res."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Lin, I.J., Tzeng, N.S., Chung, C.H., and Chien, W.C. (2021). Psychiatric disorders in female psychosexual disorders-a nationwide, cohort study in Taiwan: Psychiatric disorders and female psychosexual disorders. BMC Psychiatry, 21.","DOI":"10.1186\/s12888-021-03060-1"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"S91","DOI":"10.4103\/0019-5545.196977","article-title":"Clinical Practice Guidelines for Management of Sexual Dysfunction","volume":"59","author":"Avasthi","year":"2017","journal-title":"Indian. J. Psychiatry"},{"key":"ref_38","first-page":"645","article-title":"Health, Sexual Activity, and Sexual Satisfaction","volume":"117","author":"Dekker","year":"2020","journal-title":"Dtsch. Arztebl. Int."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1016\/S0140-6736(13)62222-9","article-title":"Associations between health and sexual lifestyles in Britain: Findings from the third National Survey of Sexual Attitudes and Lifestyles (Natsal-3)","volume":"382","author":"Field","year":"2013","journal-title":"Lancet"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1016\/j.jsxm.2016.08.011","article-title":"Sexual Satisfaction the Importance of Sexual Health to Quality of Life Throughout the Life Course of, U.S. Adults","volume":"13","author":"Flynn","year":"2016","journal-title":"J. Sex. Med."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"478","DOI":"10.2340\/00015555-2561","article-title":"Impairment of Sexual Life in 3,485 Dermatological Outpatients From a Multicentre Study in 13 European Countries","volume":"97","author":"Sampogna","year":"2017","journal-title":"Acta Derm. Venereol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"3136","DOI":"10.1111\/jocn.15375","article-title":"Dermatological diseases, sexuality and intimate relationships: A qualitative meta-synthesis","volume":"29","author":"Barisone","year":"2020","journal-title":"J. Clin. Nurs."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.annder.2019.01.021","article-title":"Psoriasis and male sexuality","volume":"146","author":"Dauendorffer","year":"2019","journal-title":"Ann. Dermatol. Venereol."},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Sim-Sim, M., Aaberg, V., G\u00f3mez-Cantarino, S., Dias, H., Caldeira, E., Soto-Fernandez, I., and Gradellini, C. (2022). Sexual Quality of Life-Female (SQoL-F): Cultural Adaptation and Validation of European Portuguese Version. Healthcare, 10.","DOI":"10.3390\/healthcare10020255"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1007\/s11695-015-1721-8","article-title":"Female Sexual Function Before and After Bariatric Surgery: A Cross-Sectional Study and Review of Literature","volume":"25","author":"Janik","year":"2015","journal-title":"Obes. Surg."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"e114","DOI":"10.1016\/j.esxm.2017.02.002","article-title":"Vaginismus Treatment: Clinical Trials Follow Up 241 Patients","volume":"5","author":"Pacik","year":"2017","journal-title":"Sex. Med."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/sm2.53","article-title":"Using an FSDS-R Item to Screen for Sexually Related Distress: A MsFLASH Analysis","volume":"3","author":"Carpenter","year":"2015","journal-title":"Sex. Med."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1177\/1557988316629641","article-title":"Psychometric Properties of the Persian Translation of the Sexual Quality of Life-Male Questionnaire","volume":"11","author":"Maasoumi","year":"2017","journal-title":"Am. J. Mens. Health"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1038\/sj.ijir.3900472","article-title":"Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction","volume":"11","author":"Rosen","year":"1999","journal-title":"Int. J. Impot. Res."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"e13480","DOI":"10.1111\/ijcp.13480","article-title":"Men\u2019s Sexual Health Questionnaire score changes vs spontaneous sexual adverse event reporting in men treated with dutasteride\/tamsulosin combination therapy for lower urinary tract symptoms secondary to benign prostatic hyperplasia: A post hoc analysis of a prospective, randomised, placebo-controlled study","volume":"74","author":"Roehrborn","year":"2020","journal-title":"Int. J. Clin. Pract."},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"Montejo, A.L. (2019). Sexuality and Mental Health: The Need for Mutual Development and Research. J. Clin. Med., 8.","DOI":"10.3390\/jcm8111794"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1111\/bjd.21055","article-title":"The associated burden of mental health conditions in alopecia areata: A population-based study in UK primary care","volume":"187","author":"Macbeth","year":"2022","journal-title":"Br. J. Dermatol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1093\/jsxmed\/qdad074","article-title":"Sexual dysfunction related to psychiatric disorders: A systematic review","volume":"20","author":"Herder","year":"2023","journal-title":"J. Sex. Med."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1097\/JCP.0b013e31819c76e9","article-title":"Sexual dysfunction, depression, and the impact of antidepressants","volume":"29","author":"Kennedy","year":"2009","journal-title":"J. Clin. Psychopharmacol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1017\/S1092852900026729","article-title":"Sexual dysfunction in major depression","volume":"11","author":"Williams","year":"2006","journal-title":"CNS Spectr."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"e010521","DOI":"10.1136\/bmjopen-2015-010521","article-title":"Are depression and poor sexual health neglected comorbidities? Evidence from a population sample","volume":"6","author":"Field","year":"2016","journal-title":"BMJ Open"},{"key":"ref_57","first-page":"21","article-title":"Anxiety and sexual dysfunction","volume":"49","author":"Kaplan","year":"1988","journal-title":"J. Clin. Psychiatry"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.1007\/s10508-023-02615-5","article-title":"Stress and Depression Are Associated with Sexual Function and Satisfaction in Young Men Who Have Sex with Men","volume":"52","author":"Mustanski","year":"2023","journal-title":"Arch. Sex. Behav."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1037\/a0019365","article-title":"The association between daily stress and sexual activity","volume":"24","author":"Bodenmann","year":"2010","journal-title":"J. Fam. Psychol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"296","DOI":"10.2340\/0001555577296298","article-title":"Stress and alopecia areata: A psychodermatologic study","volume":"77","author":"Gupta","year":"1997","journal-title":"Acta Derm. Venereol."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1590\/abd1806-4841.20186131","article-title":"Comparison of quality of life in patients with androgenetic alopecia and alopecia areata","volume":"93","author":"Gonul","year":"2018","journal-title":"An. Bras. Dermatol."},{"key":"ref_62","doi-asserted-by":"crossref","unstructured":"Krefft-Trzciniecka, K., Ciso\u0144, H., Pakiet, A., Nowicka, D., and Szepietowski, J.C. (2024). Enhancing Quality of Life and Sexual Functioning in Female Androgenetic Alopecia: Therapeutic Potential of Hair Follicle-Derived Stem Cells. Healthcare, 12.","DOI":"10.3390\/healthcare12060608"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"271","DOI":"10.4103\/ijt.ijt_93_18","article-title":"The Impact of Alopecia Areata on Sexual Quality of Life","volume":"10","author":"Li","year":"2018","journal-title":"Int. J. Trichol."},{"key":"ref_64","doi-asserted-by":"crossref","unstructured":"Mu\u00f1oz-Barba, D., D\u00edaz-Calvillo, P., de Francisco, S.H., Mart\u00ednez-Lopez, A., S\u00e1nchez-D\u00edaz, M., and Arias-Santiago, S. (2024). Comparative study on sexual dysfunction in alopecia areata: Prevalence and associated factors. J. Dtsch. Dermatol. Ges.","DOI":"10.1111\/ddg.15527"},{"key":"ref_65","doi-asserted-by":"crossref","unstructured":"S\u00e1nchez-D\u00edaz, M., D\u00edaz-Calvillo, P., Soto-Moreno, A., Molina-Leyva, A., and Arias-Santiago, S. (2022). The Impact of Sleep Quality on Mood Status and Quality of Life in Patients with Alopecia Areata: A Comparative Study. Int. J. Environ. Res. Public. Health, 19.","DOI":"10.3390\/ijerph192013126"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"197","DOI":"10.4103\/ijt.ijt_99_20","article-title":"Cumulative Life Course Impairment of Alopecia Areata","volume":"12","author":"Burns","year":"2020","journal-title":"Int. J. Trichol."},{"key":"ref_67","doi-asserted-by":"crossref","unstructured":"S\u00e1nchez-D\u00edaz, M., D\u00edaz-Calvillo, P., Ure\u00f1a-Paniego, C.A., Molina-Leyva, A., and Arias-Santiago, S. (2022). Quality of Life and Mood Status Disturbances in Cohabitants of Patients with Alopecia Areata: A Cross-Sectional Study in a Spanish Population. Int. J. Environ. Res. Public. Health, 19.","DOI":"10.3390\/ijerph192316323"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.jaad.2018.01.048","article-title":"Alopecia areata is associated with impaired health-related quality of life: A survey of affected adults and children and their families","volume":"79","author":"Liu","year":"2018","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/s41687-020-00240-7","article-title":"\u201c\u2018You lose your hair, what\u2019s the big deal?\u2019 I was so embarrassed, I was so self-conscious, I was so depressed:\u201d a qualitative interview study to understand the psychosocial burden of alopecia areata","volume":"4","author":"Aldhouse","year":"2020","journal-title":"J. Patient Rep. Outcomes"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1111\/jdv.18926","article-title":"The burden of alopecia areata: A scoping review focusing on quality of life, mental health and work productivity","volume":"37","author":"Muntyanu","year":"2023","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.jaad.2019.06.1304","article-title":"Impact of alopecia areata on psychiatric disorders: A retrospective cohort study","volume":"82","author":"Kim","year":"2020","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1007\/s10508-015-0637-7","article-title":"The Association Between Men\u2019s Sexist Attitudes and Facial Hair","volume":"45","author":"Oldmeadow","year":"2016","journal-title":"Arch. Sex. Behav."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"3575","DOI":"10.1007\/s10508-021-02087-5","article-title":"Appearance-Related Partner Preferences and Body Image in a German Sample of Homosexual and Heterosexual Women and Men","volume":"50","author":"Cordes","year":"2021","journal-title":"Arch. Sex. Behav."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"e420","DOI":"10.1002\/ski2.420","article-title":"The psychosocial impact of alopecia in men: A mixed-methods survey study","volume":"4","author":"Zucchelli","year":"2024","journal-title":"Skin. Health Dis."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1007\/s40257-023-00808-1","article-title":"Alopecia Areata: Current Treatments and New Directions","volume":"24","author":"Dahabreh","year":"2023","journal-title":"Am. J. Clin. Dermatol."},{"key":"ref_76","first-page":"262","article-title":"New aspects of the treatment of alopecia areata","volume":"31","year":"2014","journal-title":"Postep. Dermatol. Alergol."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/s12016-021-08883-0","article-title":"Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management","volume":"61","author":"Zhou","year":"2021","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1634\/theoncologist.2015-0164","article-title":"Preventing and Managing Toxicities of High-Dose Methotrexate","volume":"21","author":"Howard","year":"2016","journal-title":"Oncologist"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"14799731211031935","DOI":"10.1177\/14799731211031935","article-title":"Patient reported side-effects of prednisone and methotrexate in a real-world sarcoidosis population","volume":"18","author":"Kahlmann","year":"2021","journal-title":"Chron. Respir. Dis."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"93","DOI":"10.2147\/PTT.S159916","article-title":"Psoriasis and sexual dysfunction: Links, risks, and management challenges","volume":"8","author":"Duarte","year":"2018","journal-title":"Psoriasis"},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.2340\/00015555-2714","article-title":"Methotrexate-associated Sexual Dysfunction: Two Case Reports","volume":"97","author":"Theodosiou","year":"2017","journal-title":"Acta Derm. Venereol."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.jaad.2019.03.043","article-title":"Sexual dysfunction in men taking systemic dermatologic medication: A systematic review","volume":"81","author":"Zakhem","year":"2019","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s13555-020-00370-2","article-title":"Cyclosporine With and Without Systemic Corticosteroids in Treatment of Alopecia Areata: A Systematic Review","volume":"10","author":"Nowaczyk","year":"2020","journal-title":"Dermatol. Ther."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1097\/00029330-200805010-00009","article-title":"Prevalence and influential factors of erectile dysfunction in male renal transplant recipients: A multiple center survey","volume":"121","author":"Tian","year":"2008","journal-title":"Chin. Med. J."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1055\/s-2003-37499","article-title":"Unilateral adrenal tumor, erectile dysfunction and infertility in a patient with 21-hydroxylase deficiency: Effects of glucocorticoid treatment and surgery","volume":"111","author":"Scaroni","year":"2003","journal-title":"Exp. Clin. Endocrinol. Diabetes"},{"key":"ref_86","first-page":"43","article-title":"Glucocorticoids: Their role on gonadal function and LH secretion","volume":"21","author":"Contreras","year":"1996","journal-title":"Minerva Endocrinol."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1111\/all.15071","article-title":"Phase 2a randomized clinical trial of dupilumab (anti-IL-4R\u03b1) for alopecia areata patients","volume":"77","author":"Bares","year":"2022","journal-title":"Allergy"},{"key":"ref_88","doi-asserted-by":"crossref","unstructured":"Napolitano, M., Fabbrocini, G., Kastl, S., Battista, T., Di Guida, A., Martora, F., Picone, V., Ventura, V., and Patruno, C. (2022). Effect of Dupilumab on Sexual Desire in Adult Patients with Moderate to Severe Atopic Dermatitis. Medicina, 58.","DOI":"10.3390\/medicina58121708"},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1016\/j.jisp.2017.10.013","article-title":"Treatment of Alopecia Areata with Simvastatin\/Ezetimibe","volume":"19","author":"Cervantes","year":"2018","journal-title":"J. Investig. Dermatol. Symp. Proc."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1111\/j.1464-410X.2012.11241.x","article-title":"Can simvastatin improve erectile function and health-related quality of life in men aged \u226540 years with erectile dysfunction? Results of the Erectile Dysfunction and Statins Trial [ISRCTN66772971]","volume":"111","author":"Trivedi","year":"2013","journal-title":"BJU Int."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"129","DOI":"10.15557\/PiPK.2017.0015","article-title":"Cognitive-behavioural psychotherapy and alopecia areata","volume":"17","year":"2017","journal-title":"Psychiatr. Psychol. Klin."},{"key":"ref_92","doi-asserted-by":"crossref","unstructured":"Maloh, J., Engel, T., Natarelli, N., Nong, Y., Zufall, A., and Sivamani, R.K. (2023). Systematic Review of Psychological Interventions for Quality of Life, Mental Health, and Hair Growth in Alopecia Areata and Scarring Alopecia. J. Clin. Med., 12.","DOI":"10.3390\/jcm12030964"},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1017\/S1352465823000292","article-title":"The effectiveness of mindfulness-based cognitive therapy for social anxiety symptoms in people living with alopecia areata: A single-group case-series design","volume":"51","author":"Heapy","year":"2023","journal-title":"Behav. Cogn. Psychother."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"30","DOI":"10.12809\/eaap1736","article-title":"Sexuality in the 21st Century: Sexual Fluidity","volume":"29","author":"Ventriglio","year":"2019","journal-title":"East. Asian Arch. Psychiatry"},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"S296","DOI":"10.4103\/0019-5545.161496","article-title":"Female sexuality","volume":"57","author":"Rao","year":"2015","journal-title":"Indian. J. Psychiatry"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/8\/2602\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T17:12:09Z","timestamp":1760029929000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/8\/2602"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,10]]},"references-count":95,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2025,4]]}},"alternative-id":["jcm14082602"],"URL":"https:\/\/doi.org\/10.3390\/jcm14082602","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,10]]}}}