{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T05:59:59Z","timestamp":1792130399537,"version":"4.4.0"},"reference-count":58,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T00:00:00Z","timestamp":1744329600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Arthrogenic muscle inhibition (AMI) is a neuromuscular impairment commonly observed following anterior cruciate ligament reconstruction (ACLR). This condition, characterized by persistent quadricep inhibition due to altered afferent feedback, significantly impacts neuromuscular recovery, delaying return to running and sport. Despite advancements in rehabilitation strategies, AMI may persist for months or even years after ACLR, leading to muscle strength asymmetries, altered biomechanics, and an increased risk of reinjury. The mechanisms underlying AMI involve both peripheral (joint effusion, mechanoreceptor dysfunction) and central (corticospinal inhibition, neuroplasticity alterations) components, which collectively hinder voluntary muscle activation and movement control. AMI alters gait mechanics, reduces knee stability, and promotes compensatory patterns that increase injury risk. Current return-to-sport protocols emphasize strength symmetry and functional performance but often neglect neuromuscular deficits. A comprehensive assessment integrating neuromuscular, biomechanical, and proprioceptive evaluations is needed at specific stages to optimize rehabilitation and minimize reinjury risk. Future research should explore targeted interventions such as neuromuscular stimulation, cognitive\u2013motor training, and advanced gait analysis to mitigate AMI\u2019s impact and facilitate a safer, more effective return to sport.<\/jats:p>","DOI":"10.3390\/jcm14082633","type":"journal-article","created":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T10:05:51Z","timestamp":1744365951000},"page":"2633","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Rethinking the Assessment of Arthrogenic Muscle Inhibition After ACL Reconstruction: Implications for Return-to-Sport Decision-Making\u2014A Narrative Review"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8650-2746","authenticated-orcid":false,"given":"Florian","family":"Forelli","sequence":"first","affiliation":[{"name":"Haute-Ecole Arc Sant\u00e9, HES-SO University of Applied Sciences and Arts Western Switzerland, 2800 Del\u00e9mont, Switzerland"},{"name":"Orthopaedic Surgery Department, Clinic of Domont, Ramsay Healthcare, @OrthoLab, 95330 Domont, France"},{"name":"Soci\u00e9t\u00e9 Fran\u00e7aise des Masseurs\u2014Kin\u00e9sith\u00e9rapeutes du Sport Lab, 93380 Pierrefite sur Seine, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2654-2195","authenticated-orcid":false,"given":"Ayrton","family":"Moiroux-Sahraoui","sequence":"additional","affiliation":[{"name":"Orthopaedic Surgery Department, Clinic of Domont, Ramsay Healthcare, @OrthoLab, 95330 Domont, France"},{"name":"Orthosport Rehab Center, 95330 Domont, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6322-7091","authenticated-orcid":false,"given":"Jean","family":"Mazeas","sequence":"additional","affiliation":[{"name":"Orthopaedic Surgery Department, Clinic of Domont, Ramsay Healthcare, @OrthoLab, 95330 Domont, France"},{"name":"Orthosport Rehab Center, 95330 Domont, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6567-8523","authenticated-orcid":false,"given":"Jonathan","family":"Dugernier","sequence":"additional","affiliation":[{"name":"Haute-Ecole Arc Sant\u00e9, HES-SO University of Applied Sciences and Arts Western Switzerland, 2800 Del\u00e9mont, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrien","family":"Cerrito","sequence":"additional","affiliation":[{"name":"Haute-Ecole Arc Sant\u00e9, HES-SO University of Applied Sciences and Arts Western Switzerland, 2800 Del\u00e9mont, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"141","DOI":"10.5435\/00124635-200005000-00001","article-title":"Noncontact Anterior Cruciate Ligament Injuries: Risk Factors and Prevention Strategies","volume":"8","author":"Griffin","year":"2000","journal-title":"J. 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