{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T15:41:30Z","timestamp":1791819690402,"version":"4.3.4"},"reference-count":71,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T00:00:00Z","timestamp":1744934400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Despite a combination of medical and surgical treatments, many patients with perianal Crohn\u2019s disease (CD) continue to experience refractory disease, requiring proctectomy or proctocolectomy, with the creation of a permanent stoma. Although proctectomy is seen as an ultimate treatment aimed at effectively relieving debilitating symptoms and enhancing quality of life, many patients may still face long-term and chronic complications. This narrative review aims to provide an overview of the main complications that patients undergoing proctectomy for CD may experience throughout their lives. Relevant publications addressing complications of proctectomy for refractory perianal CD were searched in the Medline\/PubMed, Embase, Cochrane, and LILACS databases. The main long-term complications that patients encounter are related to impaired perineal wound healing, stoma-related issues, sexual and urinary dysfunction, small bowel obstructions, and CD recurrence. These complications negatively affect the quality of life and frequently necessitate further treatment. Patients should receive preoperative counselling regarding the implications of these particular issues, and regular follow-up must be guaranteed to identify any problems early, allowing for prompt treatment.<\/jats:p>","DOI":"10.3390\/jcm14082802","type":"journal-article","created":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T08:24:07Z","timestamp":1744964647000},"page":"2802","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Long-Term Complications of Proctectomy for Refractory Perianal Crohn\u2019s Disease: A Narrative Review"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7305-2341","authenticated-orcid":false,"given":"Bruno Augusto","family":"Alves Martins","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery, Hospital Universit\u00e1rio de Bras\u00edlia, Federal District, Brasilia 70330-750, Brazil"},{"name":"Medical Sciences Postgraduate Program, School of Medicine, University of Brasilia, Federal District, Brasilia 70910-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana Trotta","family":"Villar","sequence":"additional","affiliation":[{"name":"Medical Sciences Postgraduate Program, School of Medicine, University of Brasilia, Federal District, Brasilia 70910-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luna Vit\u00f3ria Gondim","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Medical Sciences Postgraduate Program, School of Medicine, University of Brasilia, Federal District, Brasilia 70910-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz da Costa Rossi","family":"Ramos de Carvalho","sequence":"additional","affiliation":[{"name":"Medical Sciences Postgraduate Program, School of Medicine, University of Brasilia, Federal District, Brasilia 70910-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Avellaneda","sequence":"additional","affiliation":[{"name":"Department of General Surgery and Academic Investigations Unit, CEMIC University Hospital, Buenos Aires C1430EFA, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6314-9505","authenticated-orcid":false,"given":"Jo\u00e3o Batista","family":"de Sousa","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Hospital Universit\u00e1rio de Bras\u00edlia, Federal District, Brasilia 70330-750, Brazil"},{"name":"Medical Sciences Postgraduate Program, School of Medicine, University of Brasilia, Federal District, Brasilia 70910-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1016\/S0140-6736(16)31711-1","article-title":"Crohn\u2019s disease","volume":"389","author":"Torres","year":"2017","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1097\/DCR.0b013e31825228b0","article-title":"The Spectrum of Perianal Crohn\u2019s Disease in a Population-Based Cohort","volume":"55","author":"Eglinton","year":"2012","journal-title":"Dis. 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