{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T03:13:10Z","timestamp":1788491590215,"version":"build-2803163510"},"reference-count":26,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T00:00:00Z","timestamp":1746576000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Objectives: We aimed to evaluate the condition of retained primary molars in case of mandibular second premolar agenesis. Materials and Methods: In total, 2692 panoramic radiographs of adolescent patients were analyzed to determine the prevalence of tooth agenesis. Patients (N = 156) with at least one mandibular second premolar agenesis were further explored to determine the presence and condition of retained primary teeth. Teeth were classified as good or poor based on root resorption, infraocclusion, caries, and restorations. Results: The prevalence of mandibular second premolar agenesis was 5.8% (N = 156). For the set period for this study, 138 (58.5%) primary molars were present. Out of these retained teeth, N = 83 were in good condition. There was a statistically significant positive weak correlation between age and the level of root resorption (rs = 0.348, n = 138, p &lt; 0.001). There was no association between infraocclusion and the level of root resorption (p = 0.747). Signs of infraocclusion were noted in 32 out of 138 teeth. There was no association between gender and the presence of infraocclusion (p = 0.067) and the presence or lack of infraocclusion and the therapeutic status of a tooth (p = 0.450). Only 28 out of 138 (20.3%) were intact. There was a significant difference in the level of root resorption between restored and\/or carious (median = 3, IQR 2\u20134) and intact teeth (median = 2, IQR 1.75\u20133), U = 1168, p = 0.044, r = 0.242. Conclusions: Overall, 35.2% of corresponding primary molars were present in oral cavity, and were in good condition, and could potentially be preserved in the long term.<\/jats:p>","DOI":"10.3390\/jcm14093241","type":"journal-article","created":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T08:20:53Z","timestamp":1746606053000},"page":"3241","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Radiological Evaluation of Retained Primary Molars in Adolescents with Mandibular Second Premolar Agenesis"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6047-8191","authenticated-orcid":false,"given":"Dita","family":"Meistere","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry and Oral Health, Riga Stradins University, LV1007 Riga, Latvia"},{"name":"Institute of Stomatology, Riga Stradins University, LV1007 Riga, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandra","family":"Karkle","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Oral Health, Riga Stradins University, LV1007 Riga, Latvia"},{"name":"Institute of Stomatology, Riga Stradins University, LV1007 Riga, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0076-6396","authenticated-orcid":false,"given":"Sindija","family":"Mengele","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Oral Health, Riga Stradins University, LV1007 Riga, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liga","family":"Kronina","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Oral Health, Riga Stradins University, LV1007 Riga, Latvia"},{"name":"Institute of Stomatology, Riga Stradins University, LV1007 Riga, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5411-5810","authenticated-orcid":false,"given":"Laura","family":"Neimane","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Oral Health, Riga Stradins University, LV1007 Riga, Latvia"},{"name":"Institute of Stomatology, Riga Stradins University, LV1007 Riga, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,5,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Al-Ani, A.H., Antoun, J.S., Thomson, W.M., Merriman, T.R., and Farella, M. (2017). Hypodontia: An Update on Its Etiology, Classification, and Clinical Management. BioMed Res. Int., 2017.","DOI":"10.1155\/2017\/9378325"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1179\/1465313314Y.0000000116","article-title":"Prevalence of hypodontia and associated factors: A systematic review and meta-analysis","volume":"41","author":"Khalaf","year":"2014","journal-title":"J. Orthod."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"110","DOI":"10.2319\/123020-1039.1","article-title":"What is the survival rate of deciduous molars in cases with agenesis of premolar successors? A systematic review","volume":"92","author":"Melo","year":"2022","journal-title":"Angle Orthod."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1093\/ejo\/cjs105","article-title":"The prognosis of retained primary molars without successors: Infraocclusion, root resorption and restorations in 111 patients","volume":"36","author":"Hvaring","year":"2014","journal-title":"Eur. J. Orthod."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"S125","DOI":"10.4103\/jpbs.jpbs_414_23","article-title":"Mandibular Second Premolar Agenesis: A Retrospective Cross-sectional Study from Palestine","volume":"16","author":"Arandi","year":"2024","journal-title":"J. Pharm. Bioallied Sci."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1093\/ejo\/22.3.245","article-title":"The long-term survival of lower second primary molars in subjects with agenesis of the premolars","volume":"22","author":"Bjerklin","year":"2000","journal-title":"Eur. J. Orthod."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1093\/ejo\/cjn027","article-title":"Agenesis of mandibular second premolars with retained primary molars. A longitudinal radiographic study of 99 subjects from 12 years of age to adulthood","volume":"30","author":"Bjerklin","year":"2008","journal-title":"Eur. J. Orthod."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1093\/ejo\/cjz090","article-title":"The long-term fate of persisting deciduous molars and canines in 42 patients with severe hypodontia: A 12-year follow-up","volume":"42","author":"Hvaring","year":"2020","journal-title":"Eur. J. Orthod."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1093\/ejo\/22.3.239","article-title":"Persistence of deciduous molars in subjects with agenesis of the second premolars","volume":"22","year":"2000","journal-title":"Eur. J. Orthod."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.ajodo.2003.07.002","article-title":"Retained deciduous mandibular molars in adults: A radiographic study of long-term changes","volume":"124","author":"Sletten","year":"2003","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1093\/ejo\/cjm123","article-title":"Can persistence of primary molars be predicted in subjects with multiple tooth agenesis? Eur J Orthod","volume":"30","author":"Kjaer","year":"2008","journal-title":"Eur. J. Orthod."},{"key":"ref_12","first-page":"262","article-title":"Status of retained deciduous second molars in subjects with agenesis of second premolars in relation to age","volume":"24","author":"Bilinska","year":"2023","journal-title":"Eur. J. Paediatr. Dent."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1046\/j.1365-263X.2001.00257.x","article-title":"Root resorption in retained deciduous canine and molar teeth without permanent successors in patients with severe hypodontia","volume":"11","author":"Haselden","year":"2001","journal-title":"Int. J. Paediatr. Dent."},{"key":"ref_14","first-page":"2","article-title":"The Current Evidence on Retaining or Prosthodontically Replacing Retained Deciduous Teeth in the Adult Hypodontia Patient: A Systematic Review","volume":"26","author":"Laverty","year":"2018","journal-title":"Eur. J. Prosthodont. Restor. Dent."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Akg\u00f6l, B.B., \u00dcst\u00fcn, N., and Bayram, M. (2024). Characterizing infraocclusion in primary molars: Prevalence, accompanying findings, and infraocclusion severity and treatment implications. BMC Oral Health, 24.","DOI":"10.1186\/s12903-024-04428-x"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s40368-024-00901-x","article-title":"Non-syndromic tooth agenesis in Latvian adolescent dental patients: A retrospective study with relevant literature review","volume":"25","author":"Meistere","year":"2024","journal-title":"Eur. Arch. Paediatr. Dent."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"714","DOI":"10.2174\/1874210601610010714","article-title":"Etiology, Diagnosis, Consequences and Treatment of Infraoccluded Primary Molars","volume":"10","author":"Arhakis","year":"2016","journal-title":"Open Dent. J."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"182","DOI":"10.15311\/selcukdentj.939183","article-title":"Prevalence of Mandibular Second Premolar Agenesis in Individuals and Associated Factors: A Meta-Analysis","volume":"9","year":"2022","journal-title":"Selcuk Dent. J."},{"key":"ref_19","first-page":"110","article-title":"Correlation of root resorption and infraocclusion in mandibular deciduous second molars without succedaneous permanent teeth","volume":"3","author":"Garib","year":"2014","journal-title":"J. World Fed. Orthod."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1111\/idj.12627","article-title":"Caries Prevalence and Severity for 12-Year-Old Children in Latvia","volume":"71","author":"Maldupa","year":"2021","journal-title":"Int. Dent. J."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2334\/josnusd.49.1","article-title":"Physiologic root resorption in primary teeth: Molecular and histological events","volume":"49","year":"2007","journal-title":"J. Oral Sci."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"195","DOI":"10.17219\/dmp\/146256","article-title":"Infraocclusion level and root resorption of the primary molar in second premolar agenesis: A retrospective cross-sectional study in the Portuguese population","volume":"59","author":"Costa","year":"2022","journal-title":"Dent. Med. Probl."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1093\/ejo\/cjq189","article-title":"An evaluation of factors associated with persistent primary teeth","volume":"34","author":"Aktan","year":"2012","journal-title":"Eur. J. Orthod."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"29951683","DOI":"10.1259\/dmfr\/29951683","article-title":"Object position and image magnification in dental panoramic radiography: A theoretical analysis","volume":"42","author":"Devlin","year":"2013","journal-title":"Dentomaxillofac. Radiol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1046\/j.0960-7439.2001.00294.x","article-title":"A treatment decision-making model for infraoccluded primary molars","volume":"11","author":"Ekim","year":"2001","journal-title":"Int. J. Paediatr. Dent."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1590\/S1806-83242012000400009","article-title":"Inflammatory root resorption in primary molars: Prevalence and associated factors","volume":"26","author":"Drumond","year":"2012","journal-title":"Braz. Oral Res."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/9\/3241\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T17:28:42Z","timestamp":1760030922000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/9\/3241"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,7]]},"references-count":26,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2025,5]]}},"alternative-id":["jcm14093241"],"URL":"https:\/\/doi.org\/10.3390\/jcm14093241","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,7]]}}}