{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:14:36Z","timestamp":1760058876503,"version":"build-2065373602"},"reference-count":66,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T00:00:00Z","timestamp":1746748800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Peripheral vein thrombosis during pregnancy poses serious diagnostic challenges due to the intertwining of its clinical symptoms with normal pregnancy modifications. Methods: We analyzed and compared the paraclinical test results of singleton pregnant women and women in the first six weeks postpartum who presented with significant lower limb inequality. Results: Our data revealed three predictors of deep vein thrombosis (DVT): mean platelet volume (MPV), with a one-unit increase in MPV being associated with a 1.497-fold higher risk of thrombosis (p = 0.008); platelet distribution width (PDW), with a one-unit decrease in PDW increasing thrombosis risk (odds ratio (OR) = 1.17, p = 0.003); anemia, with its presence increasing the risk of thrombosis by 8.46 times (p = 0.003); and fibrinogen, with a one-unit increase in its level increasing DVT risk 1.003-fold. Conclusions: Significant lower limb inequality might be used as a predictor of DVT during puerperium.<\/jats:p>","DOI":"10.3390\/jcm14103320","type":"journal-article","created":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T11:25:53Z","timestamp":1746789953000},"page":"3320","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Predictive Value of Centered Clinical Asymmetric Lower Limb Edema in Diagnosing Deep Vein Thrombosis in Puerperium"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2132-6742","authenticated-orcid":false,"given":"Catalina","family":"Filip","sequence":"first","affiliation":[{"name":"Department of Vascular Surgery, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700111 Iasi, Romania"},{"name":"Department of Vascular Surgery, CHU \u201cGabriel Montpied\u201d, 63000 Clermont-Ferrand, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2862-2069","authenticated-orcid":false,"given":"Daniela Roxana","family":"Matasariu","sequence":"additional","affiliation":[{"name":"Department of Mother and Child Medicine, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700111 Iasi, Romania"},{"name":"Department of Obstetrics and Gynecology, Cuza Voda Hospital, 700038 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8207-7655","authenticated-orcid":false,"given":"Alexandra","family":"Ursache","sequence":"additional","affiliation":[{"name":"Department of Mother and Child Medicine, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700111 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Furnica","sequence":"additional","affiliation":[{"name":"Department of Morpho-Functional Sciences I, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700111 Iasi, Romania"},{"name":"Institute of Forensic Medicine, 700455 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel Ioan","family":"Anton","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Cuza Voda Hospital, 700038 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristiana","family":"Filip","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700111 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5825-6189","authenticated-orcid":false,"given":"Vasile Lucian","family":"Boiculese","sequence":"additional","affiliation":[{"name":"Biostatistics, Department of Preventive Medicine and Interdisciplinarity, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700111 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Demetra Gabriela","family":"Socolov","sequence":"additional","affiliation":[{"name":"Department of Mother and Child Medicine, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700111 Iasi, Romania"},{"name":"Department of Obstetrics and Gynecology, Cuza Voda Hospital, 700038 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raluca Ozana","family":"Chistol","sequence":"additional","affiliation":[{"name":"Department of Morpho-Functional Sciences I, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700111 Iasi, Romania"},{"name":"Department of Medical Imaging, \u201cProf. Dr. George I.M. Georgescu\u201d Cardiovascular Diseases Institute, 700503 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,5,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.jtha.2024.09.029","article-title":"Thrombotic complications in pregnancy: A case-based review of the evidence","volume":"23","author":"Merz","year":"2025","journal-title":"J. Thromb. 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