{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:16:50Z","timestamp":1760059010500,"version":"build-2065373602"},"reference-count":34,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T00:00:00Z","timestamp":1747094400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: The main goal of this study was to determine whether ductal constriction in the third trimester of a pregnancy during fetal echocardiography examination has an impact on the neonatal clinical condition during the first days after birth. Methods: A retrospective study was based on 348 newborns who were examined during their fetal life in the third trimester of a pregnancy in our fetal cardiology center. They were divided into two groups: the study group (n = 49): neonates with \u201cnormal heart anatomy\u201d (NHA), assessed by fetal echocardiography (ECHO) examination and prenatally diagnosed ductal constriction (NHA-DC); and the control group (n = 299): NHA neonates without DC (NHA-NDC). Results: Prenatally, DC was associated with other functional abnormalities, such as myocardial hypertrophy, cardiomegaly, tricuspid regurgitation, pericardial effusion and abnormal flow through foramen ovale. Neonates with prenatally diagnosed DC in 43% of cases presented with elevated neonatal bilirubin levels requiring phototherapy treatment (p &lt; 0.006). In the study group 27% of neonates showed signs of breathing difficulties in the first hours of life (p &lt; 0.001). Neonates with a prenatal diagnosis of DC were hospitalized longer than neonates with a normal heart study (NHS) (p &lt; 0.001). Conclusions: Neonates with a prenatal diagnosis of ductal constriction are prone to having transient respiratory problems (up to 27%) and mild neonatal hyperbilirubinemia (in presented series up to 43%). Gestational diabetes can be associated with ductal constriction.<\/jats:p>","DOI":"10.3390\/jcm14103388","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T06:40:23Z","timestamp":1747118423000},"page":"3388","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prenatal Diagnosis of Ductal Constriction in Normal Heart Anatomy\u2014Are There Any Neonatal Consequences?"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-5571-8535","authenticated-orcid":false,"given":"\u0141ucja Hanna","family":"Bia\u0142y","sequence":"first","affiliation":[{"name":"Students\u2019 Prenatal Cardiology Scientific Group, Medical University of \u0141\u00f3d\u017a, 92-213 \u0141\u00f3d\u017a, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomasz","family":"Talar","sequence":"additional","affiliation":[{"name":"Neonatology Department, Polish Mother\u2019s Memorial Hospital Research Institute, 93-338 \u0141\u00f3d\u017a, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewa","family":"Gulczy\u0144ska","sequence":"additional","affiliation":[{"name":"Neonatology Department, Polish Mother\u2019s Memorial Hospital Research Institute, 93-338 \u0141\u00f3d\u017a, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3469-7064","authenticated-orcid":false,"given":"Iwona","family":"Strzelecka","sequence":"additional","affiliation":[{"name":"Department of Prenatal Cardiology, Polish Mother\u2019s Memorial Hospital Research Institute, 93-338 \u0141\u00f3d\u017a, Poland"},{"name":"Department of Fetal Malformations Diagnosis and Prevention, Medical University of \u0141\u00f3d\u017a, 92-213 \u0141\u00f3d\u017a, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0238-2172","authenticated-orcid":false,"given":"Maria","family":"Respondek-Liberska","sequence":"additional","affiliation":[{"name":"Department of Prenatal Cardiology, Polish Mother\u2019s Memorial Hospital Research Institute, 93-338 \u0141\u00f3d\u017a, Poland"},{"name":"Department of Fetal Malformations Diagnosis and Prevention, Medical University of \u0141\u00f3d\u017a, 92-213 \u0141\u00f3d\u017a, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,5,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.siny.2018.03.001","article-title":"Ductus arteriosus and fetal echocardiography: Implications for practice","volume":"23","author":"Alvarez","year":"2018","journal-title":"Semin. 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