{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T22:57:45Z","timestamp":1788217065380,"version":"build-2803163510"},"reference-count":59,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:00:00Z","timestamp":1747180800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministry of Health, Italy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background and Objectives: Post-stroke aphasia (PSA) severely limits communication and quality of life. This case study explores the impact of an integrated Neurologic Music Therapy (NMT) approach, combining Melodic Intonation Therapy (MIT) and Therapeutic Singing (TS), on language recovery and brain reorganization in a 59-year-old woman with non-fluent motor aphasia following an ischemic stroke. Methods: Over 8 weeks, the patient underwent 24 sessions of MIT alongside standard speech therapy. Language abilities were assessed using the Western Aphasia Battery-Revised, while fMRI scans captured neurophysiological changes pre- and post-intervention. Results: The results showed significant language improvements: spontaneous speech increased by 68.9%, auditory comprehension by 30.8%, and naming by 83.3%. The Aphasia Quotient rose from 39.3 to 61.4, marking a shift from severe to moderate aphasia. Neuroimaging revealed heightened activation in both hemispheres, especially in the superior frontal and parietal regions, supplementary motor area, and superior temporal gyrus. Increased engagement of the limbic system, particularly the paracingulate gyrus, pointed to emotional involvement and widespread cortical reorganization. Conclusions: These findings highlight the effectiveness of integrating MIT and TS with emotionally meaningful music, supporting language recovery and neural plasticity in PSA.<\/jats:p>","DOI":"10.3390\/jcm14103436","type":"journal-article","created":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T12:22:17Z","timestamp":1747225337000},"page":"3436","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The Use of Neurologic Music Therapy in Post-Stroke Aphasia Recovery: A Case Report on Linguistic Improvements and fMRI Correlates"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1348-9442","authenticated-orcid":false,"given":"Federica","family":"Impellizzeri","sequence":"first","affiliation":[{"name":"IRCCS Centro Neurolesi Bonino Pulejo, SS 113 C.da Casazza, 98124 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0757-2389","authenticated-orcid":false,"given":"Maria Grazia","family":"Maggio","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi Bonino Pulejo, SS 113 C.da Casazza, 98124 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0282-405X","authenticated-orcid":false,"given":"Lilla","family":"Bonanno","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi Bonino Pulejo, SS 113 C.da Casazza, 98124 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Thaut","sequence":"additional","affiliation":[{"name":"Music and Health Science Research Collaboratory, Faculty of Music, University of Toronto, Toronto, ON M5S 1C5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corene","family":"Hurt","sequence":"additional","affiliation":[{"name":"Music and Health Science Research Collaboratory, Faculty of Music, University of Toronto, Toronto, ON M5S 1C5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Quartarone","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi Bonino Pulejo, SS 113 C.da Casazza, 98124 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8566-3166","authenticated-orcid":false,"given":"Rocco Salvatore","family":"Calabr\u00f2","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi Bonino Pulejo, SS 113 C.da Casazza, 98124 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,5,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"108044","DOI":"10.1016\/j.clineuro.2023.108044","article-title":"Altered functional connectivity in language and non-language brain networks in patients diagnosed with acute post-stroke aphasia","volume":"235","author":"Han","year":"2023","journal-title":"Clin. 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