{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:15:47Z","timestamp":1760058947901,"version":"build-2065373602"},"reference-count":39,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T00:00:00Z","timestamp":1747267200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Objectives: The aim of this study was to evaluate the effectiveness of using low-dose atropine (ATR) at different instillation frequencies on myopia control in a low-myopia population. Methods: A retrospective cohort study was conducted, and patients using 0.01% ATR and exhibiting a myopia degree ranging from +0.00 to \u22121.00 diopter (D) were included. A total of 32 and 26 eyes from 32 and 26 individuals were included in the daily group and two-day group, respectively. The main outcomes of this study are the progression of the spherical equivalent refraction (SER) and the elongation of the axial length (AXL). The Mann\u2013Whitney U test and generalized linear model were used to perform the statistical analysis. Results: After a follow-up period of one year, the change in SER was similar between the daily group and two-day group (\u22120.24 \u00b1 0.09 versus \u22120.26 \u00b1 0.08, p = 0.393). In addition, there was an insignificant difference in AXL elongation between the daily group and two-day group (0.09 \u00b1 0.07 versus 0.10 \u00b1 0.09, p = 0.655). The trends observed in SER progression (p = 0.604) and AXL elongation (p = 0.779) were statistically identical between the daily group and the two-day group. Conclusions: The results of the two-day use of low-dose ATR regarding SER and AXL control are similar to those with the daily use of low-dose ATR in children with low myopia.<\/jats:p>","DOI":"10.3390\/jcm14103458","type":"journal-article","created":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T06:59:16Z","timestamp":1747292356000},"page":"3458","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Daily and Two-Day Usage of Low-Dose Atropine on Myopic Control in a Low-Myopia Population"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5719-0488","authenticated-orcid":false,"given":"Chia-Yi","family":"Lee","sequence":"first","affiliation":[{"name":"Institute of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan"},{"name":"Nobel Eye Institute, Taipei 10041, Taiwan"},{"name":"Department of Ophthalmology, Jen-Ai Hospital Dali Branch, Taichung 41265, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0365-7927","authenticated-orcid":false,"given":"Shun-Fa","family":"Yang","sequence":"additional","affiliation":[{"name":"Institute of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan"},{"name":"Department of Medical Research, Chung Shan Medical University Hospital, Taichung 40201, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0794-9388","authenticated-orcid":false,"given":"Jing-Yang","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Medical Research, Chung Shan Medical University Hospital, Taichung 40201, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3992-6049","authenticated-orcid":false,"given":"Ie-Bin","family":"Lian","sequence":"additional","affiliation":[{"name":"Institute of Statistical and Information Science, National Changhua University of Education, Changhua 50007, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao-Kai","family":"Chang","sequence":"additional","affiliation":[{"name":"Nobel Eye Institute, Taipei 10041, Taiwan"},{"name":"Department of Optometry, Yuanpei University of Medical Technology, Hsinchu 30015, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,5,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.ophtha.2015.11.010","article-title":"Efficacy Comparison of 16 Interventions for Myopia Control in Children: A Network Meta-analysis","volume":"123","author":"Huang","year":"2016","journal-title":"Ophthalmology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e806","DOI":"10.1016\/S2589-7500(21)00135-7","article-title":"Association between digital smart device use and myopia: A systematic review and meta-analysis","volume":"3","author":"Foreman","year":"2021","journal-title":"Lancet Digit. 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