{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T22:21:12Z","timestamp":1782858072827,"version":"3.54.5"},"reference-count":25,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T00:00:00Z","timestamp":1748563200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Jeju National University Hospital","award":["2020000300001"],"award-info":[{"award-number":["2020000300001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: This retrospective cohort study compared the outcomes (postoperative pain, morphine consumption, sleep disturbance, and function) of patients undergoing arthroscopic rotator cuff repair involving either continuous interscalene block (CISB group) or single-injection interscalene block with intravenous dexmedetomidine (SISB group) analgesia. Methods: This study included 61 patients, aged 59\u201371 years, who underwent elective arthroscopic rotator cuff repair and for whom complete electronic health records were available. Patients in the SISB group received a single-injection nerve block plus intraoperative intravenous dexmedetomidine and postoperative patient-controlled analgesia (PCA; morphine and dexmedetomidine; n = 33). Patients in the CISB group received continuous nerve block and morphine PCA (n = 28). Patient sleep disturbances, pain, total morphine consumption, and functional outcomes were evaluated postoperatively. Results: During the first 36 h postoperatively, there were no significant differences in the measured effects for patients in the two groups. Similarly, there were no significant differences in functional outcomes. However, patients in the SISB group had a significantly lower median morphine consumption total (18 mg) than those in the CISB group (24 mg; p &lt; 0.001). Conclusions: Patients in the SISB group demonstrated significantly lower median morphine consumption than those in the CISB group; however, the postoperative pain, frequency of sleep disturbances, nausea, and functional outcomes did not show statistically significant differences. The reduced morphine consumption associated with the SISB group, compared with the CISB group, suggests that this analgesic protocol may result in fewer opioid-related effects following arthroscopic rotator cuff repair.<\/jats:p>","DOI":"10.3390\/jcm14113882","type":"journal-article","created":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T10:21:49Z","timestamp":1748859709000},"page":"3882","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Comparative Arthroscopic Rotator Cuff Repair Outcomes Associated with Continuous Interscalene Block vs. Bolus Interscalene Block with Intravenous Dexmedetomidine: A Retrospective Cohort Study"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-2579-8296","authenticated-orcid":false,"given":"Seong-Meen","family":"Yoon","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery, Jeju National University Hospital, Jeju National University College of Medicine, Jeju 63241, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aeryoung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, Jeju National University Hospital, Jeju National University College of Medicine, Jeju 63241, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0319-6208","authenticated-orcid":false,"given":"Sungwook","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Jeju National University Hospital, Jeju National University College of Medicine, Jeju 63241, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,5,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1016\/j.jse.2013.01.006","article-title":"The rising incidence of rotator cuff repairs","volume":"22","author":"Ensor","year":"2013","journal-title":"J. Shoulder Elb. Surg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1302\/0301-620X.99B1.BJJ-2016-0424.R1","article-title":"Effectiveness of open and arthroscopic rotator cuff repair (UKUFF): A randomised controlled trial","volume":"99-B","author":"Carr","year":"2017","journal-title":"Bone Jt. J."},{"key":"ref_3","first-page":"133","article-title":"Prospective study of three surgical procedures for long head biceps tendinopathy associated with rotator cuff tears","volume":"2","author":"Biz","year":"2012","journal-title":"Muscles Ligaments Tendons J."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"331","DOI":"10.4103\/0259-1162.123225","article-title":"Acomparative study of the efficacy of intravenous paracetamol and dexmedetomidine on perioperative hemodynamics and post-operative analgesia for patients undergoing laparoscopic cholecystectomy","volume":"7","author":"Swaika","year":"2013","journal-title":"Anesth. Essays Res."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1111\/anae.14796","article-title":"PROSPECT guideline for rotator cuff repair surgery: Systematic review and procedure-specific postoperative pain management recommendations","volume":"74","author":"Toma","year":"2019","journal-title":"Anaesthesia"},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Chen, H.P., Shen, S.J., Tsai, H.I., Kao, S.C., and Yu, H.P. (2015). Effects of interscalene nerve block for postoperative pain management in patients after shoulder surgery. Biomed. Res. Int., 2015.","DOI":"10.1155\/2015\/902745"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1007\/s00264-018-4199-x","article-title":"Intra-operative effect of interscalene brachial plexus block to arthroscopic rotator cuff repair surgery","volume":"43","author":"Choi","year":"2019","journal-title":"Int. Orthop."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1213\/01.ane.0000436607.40643.0a","article-title":"Continuous interscalene block in patients having outpatient rotator cuff repair surgery: A prospective randomized trial","volume":"117","author":"Salviz","year":"2013","journal-title":"Anesth. Analg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1213\/ANE.0000000000000688","article-title":"Will the real benefits of single-shot interscalene block please stand up? A systematic review and meta-analysis","volume":"120","author":"Abdallah","year":"2015","journal-title":"Anesth. Analg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1097\/AAP.0b013e3181c771bd","article-title":"Analgesic effectiveness of a continuous versus single-injection interscalene block for minor arthroscopic shoulder surgery","volume":"35","author":"Fredrickson","year":"2010","journal-title":"Reg. Anesth. Pain Med."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"e7938","DOI":"10.1097\/MD.0000000000007938","article-title":"Efficacy of dexmedetomidine for pain management in knee arthroscopy: A systematic review and meta-analysis","volume":"96","author":"Li","year":"2017","journal-title":"Medicine"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.arthro.2024.06.043","article-title":"Adding dexmedetomidine to intra-articular local anesthetics results in prolonged analgesia after knee arthroscopy: A systematic review and meta-analysis","volume":"41","author":"Terres","year":"2024","journal-title":"Arthroscopy"},{"key":"ref_13","first-page":"488","article-title":"Effective dose of intravenous dexmedetomidine to prolong the analgesic duration of interscalene brachial plexus block: A single-center, prospective, double-blind, randomized controlled trial","volume":"43","author":"Kang","year":"2018","journal-title":"Reg. Anesth. Pain Med."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.2106\/JBJS.L.01116","article-title":"Interscalene brachial plexus block for arthroscopic shoulder surgery: A systematic review","volume":"95","author":"Hughes","year":"2013","journal-title":"J. Bone Jt. Surg. Am."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"3019","DOI":"10.1016\/j.arthro.2019.06.022","article-title":"Arthroscopic and open or mini-open rotator cuff repair trends and complication rates among American Board of Orthopaedic Surgeons Part II Examinees (2007\u20132017)","volume":"35","author":"Kelly","year":"2019","journal-title":"Arthroscopy"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3810\/psm.2013.09.2026","article-title":"Shoulder surgeons\u2019 perceptions of interscalene nerve blocks and a review of complications rates in the literature","volume":"41","author":"Moore","year":"2013","journal-title":"Phys. Sportsmed."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Li, H.J., Liu, S., Geng, Z.Y., and Li, X.Y. (2020). Adding dexmedetomidine to morphine-based analgesia reduces early postoperative nausea in patients undergoing gynecological laparoscopic surgery: A randomized controlled trial. BMC Anesthesiol., 20.","DOI":"10.1186\/s12871-019-0928-y"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1016\/j.pain.2013.03.029","article-title":"Is intraoperative dexmedetomidine a new option for postoperative pain treatment? A meta-analysis of randomized controlled trials","volume":"154","author":"Schnabel","year":"2013","journal-title":"Pain"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1097\/TA.0b013e3182475408","article-title":"The relationship between dexmedetomidine dosing and hypotension","volume":"72","author":"Gerlach","year":"2012","journal-title":"J. Trauma Acute Care Surg."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"3000605211039809","DOI":"10.1177\/03000605211039809","article-title":"Effect of dexmedetomidine on hemodynamics in patients undergoing hysterectomy: A meta-analysis and systematic review","volume":"49","author":"Li","year":"2021","journal-title":"J. Int. Med. Res."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1097\/AAP.0b013e3182176f70","article-title":"Neurotoxicity of adjuvants used in perineural anesthesia and analgesia in comparison with ropivacaine","volume":"36","author":"Williams","year":"2011","journal-title":"Reg. Anesth. Pain Med."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1097\/ALN.0b013e3181cf75f1","article-title":"Case scenario: Neurologic complication after continuous interscalene block","volume":"112","author":"Borgeat","year":"2010","journal-title":"Anesthesiology"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1097\/AAP.0b013e3181e8a35f","article-title":"Functional deficits after intraneural injection during interscalene block","volume":"35","author":"Cohen","year":"2010","journal-title":"Reg. Anesth. Pain Med."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"210","DOI":"10.3344\/kjp.2015.28.3.210","article-title":"Infusion methods for continuous interscalene brachial plexus block for postoperative pain control after arthroscopic rotator cuff repair","volume":"28","author":"Byeon","year":"2015","journal-title":"Korean J. Pain"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"30","DOI":"10.4097\/kjae.2012.62.1.30","article-title":"Effects of interscalene brachial plexus block to intra-operative hemodynamics and postoperative pain for arthroscopic shoulder surgery","volume":"62","author":"Lee","year":"2012","journal-title":"Korean J. Anesthesiol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/11\/3882\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T17:44:29Z","timestamp":1760031869000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/14\/11\/3882"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,30]]},"references-count":25,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2025,6]]}},"alternative-id":["jcm14113882"],"URL":"https:\/\/doi.org\/10.3390\/jcm14113882","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,30]]}}}