{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:26:24Z","timestamp":1760059584010,"version":"build-2065373602"},"reference-count":28,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T00:00:00Z","timestamp":1750377600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008021","name":"BRISTOL MYERS SQUIBB","doi-asserted-by":"publisher","award":["L1FD"],"award-info":[{"award-number":["L1FD"]}],"id":[{"id":"10.13039\/100008021","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: Dyspnoea and functional decline are common among cancer patients with associated respiratory conditions. This study aimed to evaluate the effectiveness of an Effort Re-education Programme (ERP) in improving functionality and quality of life in hospitalised oncology patients compared to Conventional Clinical Practice (CCP). Methods: A stratified, randomised, prospective clinical trial was conducted involving 65 patients with cancer and associated respiratory conditions. Participants were assigned to either a control group (CCP) or an experimental group (ERP + CCP). Functionality (Barthel Index), health-related quality of life (EORTC QLQ-C30), overall performance (Karnofsky Scale), and instrumental activities of daily living (Lawton and Brody Scale) were assessed at baseline and one month post-discharge. Results: The ERP group showed significantly greater improvements in all outcome measures: Barthel Index (mean change: +18.33 vs. +6.19), EORTC QLQ-C30 (+16.4 vs. +6.6), Karnofsky (+18.75 vs. +5.6), and Lawton\u2013Brody (+2.78 vs. +0.78), all with p &lt; 0.001 and moderate-to-large effect sizes (Cohen\u2019s d = 0.72\u20131.19). No readmissions were reported in the ERP group, versus 37.5% in the control group. Conclusions: The ERP significantly improves basic and instrumental functionality, autonomy, and health-related quality of life in oncology patients with respiratory conditions. These findings support the integration of Functional Re-education Programmes into routine clinical practice as a complement to standard care.<\/jats:p>","DOI":"10.3390\/jcm14134417","type":"journal-article","created":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T13:13:04Z","timestamp":1750425184000},"page":"4417","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Home-Based Interdisciplinary Intervention to Enhance Functionality in Oncology Patients: Results from a Clinical Trial"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2175-8545","authenticated-orcid":false,"given":"Eduardo Jos\u00e9","family":"Fern\u00e1ndez-Rodr\u00edguez","sequence":"first","affiliation":[{"name":"Department of Nursing and Physiotherapy, Universidad de Salamanca, 37008 Salamanca, Spain"},{"name":"Institute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1196-816X","authenticated-orcid":false,"given":"Celia","family":"S\u00e1nchez-G\u00f3mez","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain"},{"name":"Department of Developmental and Educational Psychology, University of Salamanca, 37007 Salamanca, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Isabel","family":"Rihuete-Galve","sequence":"additional","affiliation":[{"name":"Department of Nursing and Physiotherapy, Universidad de Salamanca, 37008 Salamanca, Spain"},{"name":"Institute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain"},{"name":"Department of Medical Oncology, University Hospital of Salamanca, 37007 Salamanca, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilio","family":"Fonseca-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain"},{"name":"Department of Medical Oncology, University Hospital of Salamanca, 37007 Salamanca, Spain"},{"name":"Department of Medicine, University of Salamanca, 37007 Salamanca, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1980-2751","authenticated-orcid":false,"given":"Juan Jes\u00fas","family":"Cruz-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain"},{"name":"Department of Medicine, University of Salamanca, 37007 Salamanca, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,6,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1038\/s41571-021-00514-z","article-title":"Planning for tomorrow: Global cancer incidence and the role of prevention 2020\u20132070","volume":"18","author":"Soerjomataram","year":"2021","journal-title":"Nat. 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