{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:30:02Z","timestamp":1760059802203,"version":"build-2065373602"},"reference-count":42,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T00:00:00Z","timestamp":1752105600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\/Objectives: Myopia is associated with peripapillary changes, namely, gamma peripapillary atrophy (\u03b3PPA) and optic disc ovalization, estimated by the ovality index (OI). These changes have been suggested to be promoted by adduction. Recent studies highlight that near reading significantly contributes to the development and progression of myopia and that the interpupillary distance (IPD) influences vergence amplitudes. While both adduction and convergence are involved during near reading, a potential link between IPD and myopic peripapillary changes has not yet been explored. We, therefore, sought to determine whether IPD is related to the OI or \u03b3PPA width. Methods: In this monocentric cross-sectional study, 100 eyes from 100 adults (mean age of 62.6 \u00b1 13.7 years) were analyzed. Axial length (AL), refractive error, and IPD were recorded. The OI and \u03b3PPA width were assessed using spectral-domain Optical Coherence Tomography. Pearson correlations and multivariable linear regressions were performed, adjusting for age, gender, and myopia status. Results: IPD showed no significant correlation with the OI (r = 0.001; p = 0.989) or \u03b3PPA (r = \u22120.028; p = 0.789). A weak, non-significant correlation was found between IPD and AL (p = 0.059). In contrast, AL was strongly correlated with both a lower OI and wider \u03b3PPA (p &lt; 0.001). Conclusions: These findings suggest that IPD-related biomechanical forces do not influence optic nerve head (ONH) shape or \u03b3PPA. Axial elongation remains the key driver of myopic ONH remodeling.<\/jats:p>","DOI":"10.3390\/jcm14144895","type":"journal-article","created":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T11:26:37Z","timestamp":1752233197000},"page":"4895","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Interpupillary Distance and Peripapillary Myopic Changes: A Pilot Study in a Glaucomatous Cohort"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-7480-6925","authenticated-orcid":false,"given":"Sameer","family":"Butt","sequence":"first","affiliation":[{"name":"Service d\u2019Ophtalmologie, H\u00f4pital Universitaire de Bruxelles (HUB), CUB H\u00f4pital Erasme, Route de Lennik 808, 1070 Bruxelles, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6796-2779","authenticated-orcid":false,"given":"Ad\u00e8le","family":"Ehongo","sequence":"additional","affiliation":[{"name":"Service d\u2019Ophtalmologie, H\u00f4pital Universitaire de Bruxelles (HUB), CUB H\u00f4pital Erasme, Route de Lennik 808, 1070 Bruxelles, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,7,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1016\/j.ophtha.2016.01.006","article-title":"Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050","volume":"123","author":"Holden","year":"2016","journal-title":"Ophthalmology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1167\/iovs.62.5.2","article-title":"IMI Impact of Myopia","volume":"62","author":"Sankaridurg","year":"2021","journal-title":"Investig. 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